Linking biosynthetic and chemical space to accelerate microbial secondary metabolite discovery

por Soldatou, Sylvia, Eldjarn, Grimur Hjorleifsson, Huerta-Uribe, Alejandro, Rogers, Simon, Duncan, Katherine R
Publicado 2019

Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition

por Zambelloni, Riccardo, Connolly, James P.R., Huerta Uribe, Alejandro, Burgess, Karl, Marquez, Rodolfo, Roe, Andrew J.
Publicado 2017

Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells

por Newman, Alice Clare, Falcone, Mattia, Huerta Uribe, Alejandro, Zhang, Tong, Athineos, Dimitris, Pietzke, Matthias, Vazquez, Alexei, Blyth, Karen, Maddocks, Oliver David Kenneth
Publicado 2021

Identification and Characterization of Novel Compounds Blocking Shiga Toxin Expression in Escherichia coli O157:H7

por Huerta-Uribe, Alejandro, Marjenberg, Zoe R., Yamaguchi, Nao, Fitzgerald, Stephen, Connolly, James P. R., Carpena, Nuria, Uvell, Hanna, Douce, Gillian, Elofsson, Michael, Byron, Olwyn, Marquez, Rudi, Gally, David L., Roe, Andrew J.
Publicado 2016

Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade

por Mahmood, Mahnoor, Liu, Eric Minwei, Shergold, Amy L., Tolla, Elisabetta, Tait-Mulder, Jacqueline, Huerta Uribe, Alejandro, Shokry, Engy, Young, Alex L., Lilla, Sergio, Kim, Minsoo, Park, Tricia, Manchon, J.L., Rodríguez-Antona, Crístina, Walters, Rowan C., Springett, Roger J., Blaza, James N., Zanivan, Sara, Sumpton, David, Roberts, Edward W., Reznik, Ed, Gammage, Payam A.
Publicado 2023

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

por Vande Voorde, Johan, Steven, Rory T., Najumudeen, Arafath K., Ford, Catriona A., Dexter, Alex, Gonzalez-Fernandez, Ariadna, Nikula, Chelsea J., Xiang, Yuchen, Ford, Lauren, Maneta Stavrakaki, Stefania, Gilroy, Kathryn, Zeiger, Lucas B., Pennel, Kathryn, Hatthakarnkul, Phimmada, Elia, Efstathios A., Nasif, Ammar, Murta, Teresa, Manoli, Eftychios, Mason, Sam, Gillespie, Michael, Lannagan, Tamsin R. M., Vlahov, Nikola, Ridgway, Rachel A., Nixon, Colin, Raven, Alexander, Mills, Megan, Athineos, Dimitris, Kanellos, Georgios, Nourse, Craig, Gay, David M., Hughes, Mark, Burton, Amy, Yan, Bin, Sellers, Katherine, Wu, Vincen, De Ridder, Kobe, Shokry, Engy, Huerta Uribe, Alejandro, Clark, William, Clark, Graeme, Kirschner, Kristina, Thienpont, Bernard, Li, Vivian S. W., Maddocks, Oliver D. K., Barry, Simon T., Goodwin, Richard J. A., Kinross, James, Edwards, Joanne, Yuneva, Mariia O., Sumpton, David, Takats, Zoltan, Campbell, Andrew D., Bunch, Josephine, Sansom, Owen J.
Publicado 2023