Identifying intragenic functional modules of genomic variations associated with cancer phenotypes by learning representation of association networks

por Kim, Minsu, Huffman, Jennifer E., Justice, Amy, Goethert, Ian, Agasthya, Greeshma, Danciu, Ioana
Publicado 2022

The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability

por Marioni, Riccardo E., Penke, Lars, Davies, Gail, Huffman, Jennifer E., Hayward, Caroline, Deary, Ian J.
Publicado 2014

Uncovering Networks from Genome-Wide Association Studies via Circular Genomic Permutation

por Cabrera, Claudia P., Navarro, Pau, Huffman, Jennifer E., Wright, Alan F., Hayward, Caroline, Campbell, Harry, Wilson, James F., Rudan, Igor, Hastie, Nicholas D., Vitart, Veronique, Haley, Chris S.
Publicado 2012

Rare coding variants pinpoint genes that control human hematological traits

por Mousas, Abdou, Ntritsos, Georgios, Chen, Ming-Huei, Song, Ci, Huffman, Jennifer E., Tzoulaki, Ioanna, Elliott, Paul, Psaty, Bruce M., Auer, Paul L., Johnson, Andrew D., Evangelou, Evangelos, Lettre, Guillaume, Reiner, Alexander P.
Publicado 2017

Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models

por Spiliopoulou, Athina, Nagy, Reka, Bermingham, Mairead L., Huffman, Jennifer E., Hayward, Caroline, Vitart, Veronique, Rudan, Igor, Campbell, Harry, Wright, Alan F., Wilson, James F., Pong-Wong, Ricardo, Agakov, Felix, Navarro, Pau, Haley, Chris S.
Publicado 2015

Platelet Reactivity in Individuals Over 65 Years Old Is Not Modulated by Age

por Chan, Melissa V., Chen, Ming-Huei, Barwari, Temo, Huffman, Jennifer E., Armstrong, Paul C., Hwang, Shih-Jen, Santer, Peter, Wierer, Brigitte, Mayr, Manuel, Kiechl, Stefan, Johnson, Andrew D., Willeit, Johann, Warner, Timothy D.
Publicado 2020

Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19

por Huffman, Jennifer E., Butler-Laporte, Guillaume, Khan, Atlas, Pairo-Castineira, Erola, Drivas, Theodore G., Peloso, Gina M., Nakanishi, Tomoko, Ganna, Andrea, Verma, Anurag, Baillie, J. Kenneth, Kiryluk, Krzysztof, Richards, J. Brent, Zeberg, Hugo
Publicado 2022

Local Exome Sequences Facilitate Imputation of Less Common Variants and Increase Power of Genome Wide Association Studies

por Joshi, Peter K., Prendergast, James, Fraser, Ross M., Huffman, Jennifer E., Vitart, Veronique, Hayward, Caroline, McQuillan, Ruth, Glodzik, Dominik, Polašek, Ozren, Hastie, Nicholas D., Rudan, Igor, Campbell, Harry, Wright, Alan F., Haley, Chris S., Wilson, James F., Navarro, Pau
Publicado 2013

Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program

por Peloso, Gina M., Tcheandjieu, Catherine, McGeary, John E., Posner, Daniel C., Ho, Yuk-Lam, Zhou, Jin J., Hilliard, Austin T., Joseph, Jacob, O’Donnell, Christopher J., Efird, Jimmy T., Crawford, Dana C., Wu, Wen-Chih, Arjomandi, Mehrdad, Sun, Yan V., Assimes, Themistocles L, Huffman, Jennifer E.
Publicado 2022

Genome-wide analysis of epistasis in body mass index using multiple human populations

por Wei, Wen-Hua, Hemani, Gib, Gyenesei, Attila, Vitart, Veronique, Navarro, Pau, Hayward, Caroline, Cabrera, Claudia P, Huffman, Jennifer E, Knott, Sara A, Hicks, Andrew A, Rudan, Igor, Pramstaller, Peter P, Wild, Sarah H, Wilson, James F, Campbell, Harry, Hastie, Nicholas D, Wright, Alan F, Haley, Chris S
Publicado 2012

Genetic architecture of heart failure with preserved versus reduced ejection fraction

por Joseph, Jacob, Liu, Chang, Hui, Qin, Aragam, Krishna, Wang, Zeyuan, Charest, Brian, Huffman, Jennifer E., Keaton, Jacob M., Edwards, Todd L., Demissie, Serkalem, Djousse, Luc, Casas, Juan P., Gaziano, J. Michael, Cho, Kelly, Wilson, Peter W. F., Phillips, Lawrence S., O’Donnell, Christopher J., Sun, Yan V.
Publicado 2022

PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort

por Small, Aeron M., Huffman, Jennifer E., Klarin, Derek, Lynch, Julie A., Assimes, Themistocles, DuVall, Scott, Sun, Yan V., Shere, Labiba, Natarajan, Pradeep, Gaziano, Michael, Rader, Daniel J., Wilson, Peter W. F., Tsao, Philip S., Chang, Kyong-Mi, Cho, Kelly, O’Donnell, Christopher J., Casas, Juan P., Damrauer, Scott M.
Publicado 2020

Multi-ancestry meta-analysis identifies 5 novel loci for ischemic stroke and reveals heterogeneity of effects between sexes and ancestries

por Surakka, Ida, Wu, Kuan-Han, Hornsby, Whitney, Wolford, Brooke N., Shen, Fred, Zhou, Wei, Huffman, Jennifer E., Pandit, Anita, Hu, Yao, Brumpton, Ben, Skogholt, Anne Heidi, Gabrielsen, Maiken E., Walters, Robin G., Hveem, Kristian, Kooperberg, Charles, Zöllner, Sebastian, Wilson, Peter W.F., Sutton, Nadia R., Daly, Mark J., Neale, Benjamin M., Willer, Cristen J.
Publicado 2023

General Framework for Meta‐Analysis of Haplotype Association Tests

por Wang, Shuai, Zhao, Jing Hua, An, Ping, Guo, Xiuqing, Jensen, Richard A., Marten, Jonathan, Huffman, Jennifer E., Meidtner, Karina, Boeing, Heiner, Campbell, Archie, Rice, Kenneth M., Scott, Robert A., Yao, Jie, Schulze, Matthias B., Wareham, Nicholas J., Borecki, Ingrid B., Province, Michael A., Rotter, Jerome I., Hayward, Caroline, Goodarzi, Mark O., Meigs, James B., Dupuis, Josée
Publicado 2016

The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function

por Bennett, J. Allen, Mastrangelo, Michael A., Ture, Sara K., Smith, Charles O., Loelius, Shannon G., Berg, Rachel A., Shi, Xu, Burke, Ryan M., Spinelli, Sherry L., Cameron, Scott J., Carey, Thomas E., Brookes, Paul S., Gerszten, Robert E., Sabater-Lleal, Maria, de Vries, Paul S., Huffman, Jennifer E., Smith, Nicholas L., Morrell, Craig N., Lowenstein, Charles J.
Publicado 2020

Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program

por Huang, Rose D. L., Nguyen, Xuan-Mai T., Peloso, Gina M., Trinder, Mark, Posner, Daniel C., Aragam, Krishna G., Ho, Yuk-Lam, Lynch, Julie A., Damrauer, Scott M., Chang, Kyong-Mi, Tsao, Philip S., Natarajan, Pradeep, Assimes, Themistocles, Gaziano, J. Michael, Djousse, Luc, Cho, Kelly, Wilson, Peter W. F., Huffman, Jennifer E., O’Donnell, Christopher J.
Publicado 2022

Comparative Performance of Four Methods for High-throughput Glycosylation Analysis of Immunoglobulin G in Genetic and Epidemiological Research

por Huffman, Jennifer E., Pučić-Baković, Maja, Klarić, Lucija, Hennig, René, Selman, Maurice H. J., Vučković, Frano, Novokmet, Mislav, Krištić, Jasminka, Borowiak, Matthias, Muth, Thilo, Polašek, Ozren, Razdorov, Genadij, Gornik, Olga, Plomp, Rosina, Theodoratou, Evropi, Wright, Alan F., Rudan, Igor, Hayward, Caroline, Campbell, Harry, Deelder, André M., Reichl, Udo, Aulchenko, Yurii S., Rapp, Erdmann, Wuhrer, Manfred, Lauc, Gordan
Publicado 2014

Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program

por Ashley-Koch, Allison E., Kimbrel, Nathan A., Qin, Xue J., Lindquist, Jennifer H., Garrett, Melanie E., Dennis, Michelle F., Hair, Lauren P., Huffman, Jennifer E., Jacobson, Daniel A., Madduri, Ravi K., Coon, Hilary, Docherty, Anna R., Kang, Jooeun, Mullins, Niamh, Ruderfer, Douglas M., Harvey, Philip D., McMahon, Benjamin H., Oslin, David W., Hauser, Elizabeth R., Hauser, Michael A., Beckham, Jean C.
Publicado 2023

Genomics Meets Glycomics—The First GWAS Study of Human N-Glycome Identifies HNF1α as a Master Regulator of Plasma Protein Fucosylation

por Lauc, Gordan, Essafi, Abdelkader, Huffman, Jennifer E., Hayward, Caroline, Knežević, Ana, Kattla, Jayesh J., Polašek, Ozren, Gornik, Olga, Vitart, Veronique, Abrahams, Jodie L., Pučić, Maja, Novokmet, Mislav, Redžić, Irma, Campbell, Susan, Wild, Sarah H., Borovečki, Fran, Wang, Wei, Kolčić, Ivana, Zgaga, Lina, Gyllensten, Ulf, Wilson, James F., Wright, Alan F., Hastie, Nicholas D., Campbell, Harry, Rudd, Pauline M., Rudan, Igor
Publicado 2010

A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

por O'Connell, Jared, Gurdasani, Deepti, Delaneau, Olivier, Pirastu, Nicola, Ulivi, Sheila, Cocca, Massimiliano, Traglia, Michela, Huang, Jie, Huffman, Jennifer E., Rudan, Igor, McQuillan, Ruth, Fraser, Ross M., Campbell, Harry, Polasek, Ozren, Asiki, Gershim, Ekoru, Kenneth, Hayward, Caroline, Wright, Alan F., Vitart, Veronique, Navarro, Pau, Zagury, Jean-Francois, Wilson, James F., Toniolo, Daniela, Gasparini, Paolo, Soranzo, Nicole, Sandhu, Manjinder S., Marchini, Jonathan
Publicado 2014