Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization

por Böhm, Beate, Burkhardt, Harald, Uebe, Steffen, Apel, Maria, Behrens, Frank, Reis, André, Hüffmeier, Ulrike
Publicado 2012

Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes

por Zhong, Jianghong, Scholz, Tatjana, Yau, Anthony C. Y., Guerard, Simon, Hüffmeier, Ulrike, Burkhardt, Harald, Holmdahl, Rikard
Publicado 2018

Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups

por Assmann, Gunter, Köhm, Michaela, Schuster, Volker, Behrens, Frank, Mössner, Rotraut, Magnolo, Nina, Oji, Vinzenz, Burkhardt, Harald, Hüffmeier, Ulrike
Publicado 2020

Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients

por Hüffmeier, Ulrike, Estivill, Xavier, Riveira-Munoz, Eva, Traupe, Heiko, Wendler, Jörg, Lohmann, Jörg, Böhm, Beate, Burkhardt, Harald, Reis, André
Publicado 2009

Association of β-defensin copy number and psoriasis in three cohorts of European origin

por Stuart, Philip E, Hüffmeier, Ulrike, Nair, Rajan P, Palla, Raquel, Tejasvi, Trilokraj, Schalkwijk, Joost, Elder, James T, Reis, Andre, Armour, John AL
Publicado 2012

The mutational and phenotypic spectrum of TUBA1A-associated tubulinopathy

por Hebebrand, Moritz, Hüffmeier, Ulrike, Trollmann, Regina, Hehr, Ute, Uebe, Steffen, Ekici, Arif B., Kraus, Cornelia, Krumbiegel, Mandy, Reis, André, Thiel, Christian T., Popp, Bernt
Publicado 2019

KIF3A and IL-4 are disease-specific biomarkers for psoriatic arthritis susceptibility

por Cascella, Raffaella, Strafella, Claudia, Ragazzo, Michele, Manzo, Laura, Costanza, Gaetana, Bowes, John, Hüffmeier, Ulrike, Potenza, Saverio, Sangiuolo, Federica, Reis, André, Barton, Anne, Novelli, Giuseppe, Orlandi, Augusto, Giardina, Emiliano
Publicado 2017

Genome-wide association and targeted analysis of copy number variants with psoriatic arthritis in German patients

por Uebe, Steffen, Ehrlicher, Maria, Ekici, Arif Bülent, Behrens, Frank, Böhm, Beate, Homuth, Georg, Schurmann, Claudia, Völker, Uwe, Jünger, Michael, Nauck, Matthias, Völzke, Henry, Traupe, Heiko, Krawczak, Michael, Burkhardt, Harald, Reis, André, Hüffmeier, Ulrike
Publicado 2017

Replication of a distinct psoriatic arthritis risk variant at the IL23R locus

por Budu-Aggrey, Ashley, Bowes, John, Loehr, Sabine, Uebe, Steffen, Zervou, Maria I, Helliwell, Philip, Ryan, Anthony W, Kane, David, Korendowych, Eleanor, Giardina, Emiliano, Packham, Jonathan, McManus, Ross, FitzGerald, Oliver, McHugh, Neil, Behrens, Frank, Burkhardt, Harald, Huffmeier, Ulrike, Ho, Pauline, Martin, Javier, Castañeda, Santos, Goulielmos, George, Reis, Andre, Barton, Anne
Publicado 2016

PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus

por Bowes, John, Loehr, Sabine, Budu-Aggrey, Ashley, Uebe, Steffen, Bruce, Ian N, Feletar, Marie, Marzo-Ortega, Helena, Helliwell, Philip, Ryan, Anthony W, Kane, David, Korendowych, Eleanor, Alenius, Gerd-Marie, Giardina, Emiliano, Packham, Jonathan, McManus, Ross, FitzGerald, Oliver, Brown, Matthew A, Behrens, Frank, Burkhardt, Harald, McHugh, Neil, Huffmeier, Ulrike, Ho, Pauline, Reis, Andre, Barton, Anne
Publicado 2015

Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease

por Vergnano, Marta, Mockenhaupt, Maja, Benzian-Olsson, Natashia, Paulmann, Maren, Grys, Katarzyna, Mahil, Satveer K., Chaloner, Charlotte, Barbosa, Ines A., August, Suzannah, Burden, A. David, Choon, Siew-Eng, Cooper, Hywel, Navarini, Alex A., Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Huffmeier, Ulrike, Baum, Patrick, Visvanathan, Sudha, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca
Publicado 2020

Loss-of-function myeloperoxidase mutations are associated with increased neutrophil counts and pustular skin disease

por Vergnano, Marta, Mockenhaupt, Maja, Benzian-Olsson, Natashia, Paulmann, Maren, Grys, Katarzyna, Mahil, Satveer K., Chaloner, Charlotte, Barbosa, Ines A., August, Suzannah, Burden, A. David, Choon, Siew-Eng, Cooper, Hywel, Navarini, Alex A., Reynolds, Nick J., Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Huffmeier, Ulrike, Baum, Patrick, Visvanathan, Sudha, Barker, Jonathan N., Smith, Catherine H., Capon, Francesca
Publicado 2021

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

por Hüffmeier, Ulrike, Uebe, Steffen, Ekici, Arif B., Bowes, John, Giardina, Emiliano, Korendowych, Eleanor, Juneblad, Kristina, Apel, Maria, McManus, Ross, Ho, Pauline, Bruce, Ian N., Ryan, Anthony W., Behrens, Frank, Lascorz, Jesús, Böhm, Beate, Traupe, Heiko, Lohmann, Jörg, Gieger, Christian, Wichmann, Heinz-Erich, Herold, Christine, Steffens, Michael, Klareskog, Lars, Wienker, Thomas F., FitzGerald, Oliver, Alenius, Gerd-Marie, McHugh, Neil J., Novelli, Giuseppe, Burkhardt, Harald, Barton, Anne, Reis, André
Publicado 2010

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

por Bowes, John, Budu-Aggrey, Ashley, Huffmeier, Ulrike, Uebe, Steffen, Steel, Kathryn, Hebert, Harry L., Wallace, Chris, Massey, Jonathan, Bruce, Ian N., Bluett, James, Feletar, Marie, Morgan, Ann W., Marzo-Ortega, Helena, Donohoe, Gary, Morris, Derek W., Helliwell, Philip, Ryan, Anthony W., Kane, David, Warren, Richard B., Korendowych, Eleanor, Alenius, Gerd-Marie, Giardina, Emiliano, Packham, Jonathan, McManus, Ross, FitzGerald, Oliver, McHugh, Neil, Brown, Matthew A., Ho, Pauline, Behrens, Frank, Burkhardt, Harald, Reis, Andre, Barton, Anne
Publicado 2015

Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

por Bowes, John, Budu-Aggrey, Ashley, Huffmeier, Ulrike, Uebe, Steffen, Steel, Kathryn, Hebert, Harry L., Wallace, Chris, Massey, Jonathon, Bruce, Ian N., Bluett, James, Feletar, Marie, Morgan, Ann W., Marzo-Ortega, Helena, Donohoe, Gary, Morris, Derek W., Helliwell, Philip, Ryan, Anthony W., Kane, David, Warren, Richard B., Korendowych, Eleanor, Alenius, Gerd-Marie, Giardina, Emiliano, Packham, Jonathan, McManus, Ross, FitzGerald, Oliver, McHugh, Neil, Brown, Matthew A., Ho, Pauline, Behrens, Frank, Burkhardt, Harald, Reis, Andre, Barton, Anne
Publicado 2015

Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases

por Haskamp, Stefan, Bruns, Heiko, Hahn, Madelaine, Hoffmann, Markus, Gregor, Anne, Löhr, Sabine, Hahn, Jonas, Schauer, Christine, Ringer, Mark, Flamann, Cindy, Frey, Benjamin, Lesner, Adam, Thiel, Christian T., Ekici, Arif B., von Hörsten, Stephan, Aßmann, Gunter, Riepe, Claudia, Euler, Maximilien, Schäkel, Knut, Philipp, Sandra, Prinz, Jörg C., Mößner, Rotraut, Kersting, Florina, Sticherling, Michael, Sefiani, Abdelaziz, Lyahyai, Jaber, Sondermann, Wiebke, Oji, Vinzenz, Schulz, Peter, Wilsmann-Theis, Dagmar, Sticht, Heinrich, Schett, Georg, Reis, André, Uebe, Steffen, Frey, Silke, Hüffmeier, Ulrike
Publicado 2020

EIF3F-related neurodevelopmental disorder: refining the phenotypic and expanding the molecular spectrum

por Hüffmeier, Ulrike, Kraus, Cornelia, Reuter, Miriam S., Uebe, Steffen, Abbott, Mary-Alice, Ahmed, Syed A., Rawson, Kristyn L., Barr, Eileen, Li, Hong, Bruel, Ange-Line, Faivre, Laurence, Tran Mau-Them, Frédéric, Botti, Christina, Brooks, Susan, Burns, Kaitlyn, Ward, D. Isum, Dutra-Clarke, Marina, Martinez-Agosto, Julian A., Lee, Hane, Nelson, Stanley F., Zacher, Pia, Abou Jamra, Rami, Klöckner, Chiara, McGaughran, Julie, Kohlhase, Jürgen, Schuhmann, Sarah, Moran, Ellen, Pappas, John, Raas-Rothschild, Annick, Sacoto, Maria J. Guillen, Henderson, Lindsay B., Palculict, Timothy Blake, Mullegama, Sureni V., Zghal Elloumi, Houda, Reich, Adi, Schrier Vergano, Samantha A., Wahl, Erica, Reis, André, Zweier, Christiane
Publicado 2021

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

por Dand, Nick, Mucha, Sören, Tsoi, Lam C, Mahil, Satveer K, Stuart, Philip E, Arnold, Andreas, Baurecht, Hansjörg, Burden, A David, Callis Duffin, Kristina, Chandran, Vinod, Curtis, Charles J, Das, Sayantan, Ellinghaus, David, Ellinghaus, Eva, Enerback, Charlotta, Esko, Tõnu, Gladman, Dafna D, Griffiths, Christopher E M, Gudjonsson, Johann E, Hoffman, Per, Homuth, Georg, Hüffmeier, Ulrike, Krueger, Gerald G, Laudes, Matthias, Lee, Sang Hyuck, Lieb, Wolfgang, Lim, Henry W, Löhr, Sabine, Mrowietz, Ulrich, Müller-Nurayid, Martina, Nöthen, Markus, Peters, Annette, Rahman, Proton, Reis, André, Reynolds, Nick J, Rodriguez, Elke, Schmidt, Carsten O, Spain, Sarah L, Strauch, Konstantin, Tejasvi, Trilokraj, Voorhees, John J, Warren, Richard B, Weichenthal, Michael, Weidinger, Stephan, Zawistowski, Matthew, Nair, Rajan P, Capon, Francesca, Smith, Catherine H, Trembath, Richard C, Abecasis, Goncalo R, Elder, James T, Franke, Andre, Simpson, Michael A, Barker, Jonathan N
Publicado 2017

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets

por Dand, Nick, Stuart, Philip E, Bowes, John, Ellinghaus, David, Nititham, Joanne, Saklatvala, Jake R, Teder-Laving, Maris, Thomas, Laurent F, Traks, Tanel, Uebe, Steffen, Assmann, Gunter, Baudry, David, Behrens, Frank, Billi, Allison C, Brown, Matthew A, Burkhardt, Harald, Capon, Francesca, Chung, Raymond, Curtis, Charles J, Duckworth, Michael, Ellinghaus, Eva, FitzGerald, Oliver, Gerdes, Sascha, Griffiths, Christopher E M, Gulliver, Susanne, Helliwell, Philip, Ho, Pauline, Hoffmann, Per, Holmen, Oddgeir L, Huang, Zhi-ming, Hveem, Kristian, Jadon, Deepak, Köhm, Michaela, Kraus, Cornelia, Lamacchia, Céline, Lee, Sang Hyuck, Ma, Feiyang, Mahil, Satveer K, McHugh, Neil, McManus, Ross, Modalsli, Ellen H, Nissen, Michael J, Nöthen, Markus, Oji, Vinzenz, Oksenberg, Jorge R, Patrick, Matthew T, Perez-White, Bethany E, Ramming, Andreas, Rech, Jürgen, Rosen, Cheryl, Sarkar, Mrinal K, Schett, Georg, Schmidt, Börge, Tejasvi, Trilokraj, Traupe, Heiko, Voorhees, John J, Wacker, Eike Matthias, Warren, Richard B, Wasikowski, Rachael, Weidinger, Stephan, Wen, Xiaoquan, Zhang, Zhaolin, Barton, Anne, Chandran, Vinod, Esko, Tõnu, Foerster, John, Franke, Andre, Gladman, Dafna D, Gudjonsson, Johann E, Gulliver, Wayne, Hüffmeier, Ulrike, Kingo, Külli, Kõks, Sulev, Liao, Wilson, Løset, Mari, Mägi, Reedik, Nair, Rajan P, Rahman, Proton, Reis, André, Smith, Catherine H, Di Meglio, Paola, Barker, Jonathan N, Tsoi, Lam C, Simpson, Michael A, Elder, James T
Publicado 2023