Single Domain Human Immunoglobulin Fold-Based Biomolecules

por Hufton, Simon E.
Publicado 2000

Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning

por Gaiotto, Tiziano, Hufton, Simon E.
Publicado 2016

Broad Reactivity Single Domain Antibodies against Influenza Virus and Their Applications to Vaccine Potency Testing and Immunotherapy

por Tung Yep, Andrew, Takeuchi, Yasu, Engelhardt, Othmar G., Hufton, Simon E.
Publicado 2021

International standards for monoclonal antibodies to support pre- and post-marketing product consistency: Evaluation of a candidate international standard for the bioactivities of...

por Prior, Sandra, Hufton, Simon E., Fox, Bernard, Dougall, Thomas, Rigsby, Peter, Bristow, Adrian
Publicado 2017

The Breadth of Cross Sub-Type Neutralisation Activity of a Single Domain Antibody to Influenza Hemagglutinin Can Be Increased by Antibody Valency

por Hufton, Simon E., Risley, Paul, Ball, Christina R., Major, Diane, Engelhardt, Othmar G., Poole, Stephen
Publicado 2014

Nanobodies mapped to cross-reactive and divergent epitopes on A(H7N9) influenza hemagglutinin using yeast display

por Gaiotto, Tiziano, Ramage, Walter, Ball, Christina, Risley, Paul, Carnell, George W., Temperton, Nigel, Engelhardt, Othmar G., Hufton, Simon E.
Publicado 2021

Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin

por Ramage, Walter, Gaiotto, Tiziano, Ball, Christina, Risley, Paul, Carnell, George W., Temperton, Nigel, Cheung, Chung Y., Engelhardt, Othmar G., Hufton, Simon E.
Publicado 2019

Protection From Influenza by Intramuscular Gene Vector Delivery of a Broadly Neutralizing Nanobody Does Not Depend on Antibody Dependent Cellular Cytotoxicity

por Del Rosario, Joanne Marie M., Smith, Matthew, Zaki, Kam, Risley, Paul, Temperton, Nigel, Engelhardt, Othmar G., Collins, Mary, Takeuchi, Yasuhiro, Hufton, Simon E.
Publicado 2020

Development of an ELISA-Based Potency Assay for Inactivated Influenza Vaccines Using Cross-Reactive Nanobodies

por Cheung, Chung Y., Dubey, Sitara, Hadrovic, Martina, Ball, Christina R., Ramage, Walter, McDonald, Jacqueline U., Harvey, Ruth, Hufton, Simon E., Engelhardt, Othmar G.
Publicado 2022

Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses

por Bullen, Georgia, Galson, Jacob D., Hall, Gareth, Villar, Pedro, Moreels, Lien, Ledsgaard, Line, Mattiuzzo, Giada, Bentley, Emma M., Masters, Edward W., Tang, David, Millett, Sophie, Tongue, Danielle, Brown, Richard, Diamantopoulos, Ioannis, Parthiban, Kothai, Tebbutt, Claire, Leah, Rachael, Chaitanya, Krishna, Ergueta-Carballo, Sandra, Pazeraitis, Deividas, Surade, Sachin B., Ashiru, Omodele, Crippa, Lucia, Cowan, Richard, Bowler, Matthew W., Campbell, Jamie I., Lee, Wing-Yiu Jason, Carr, Mark D., Matthews, David, Pfeffer, Paul, Hufton, Simon E., Sawmynaden, Kovilen, Osbourn, Jane, McCafferty, John, Karatt-Vellatt, Aneesh
Publicado 2021