ERα/PR crosstalk is altered in the context of the ERα Y537S mutation and contributes to endocrine therapy-resistant tumor proliferation

por Huggins, Rosemary J., Greene, Geoffrey L.
Publicado 2023

Evaluating steroid hormone receptor interactions using the live-cell NanoBRET proximity assay

por Huggins, Rosemary J, Hosfield, David, Ishag-Osman, Amira, Lee, Keemin, Ton-That, Elia, Greene, Geoffrey L.
Publicado 2023

Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells

por Semina, Svetlana E., Pal, Purab, Kansara, Nidhi S., Huggins, Rosemary J., Alarid, Elaine T., Greene, Geoffrey L., Frasor, Jonna
Publicado 2022

Endocrine Therapy-Resistant Breast Cancer Cells Are More Sensitive to Ceramide Kinase Inhibition and Elevated Ceramide Levels Than Therapy-Sensitive Breast Cancer Cells

por Pal, Purab, Millner, Alec, Semina, Svetlana E., Huggins, Rosemary J., Running, Logan, Aga, Diana S., Tonetti, Debra A., Schiff, Rachel, Greene, Geoffrey L., Atilla-Gokcumen, G. Ekin, Frasor, Jonna
Publicado 2022