Macrophages and angiogenesis: a role for Wnt signaling

por Newman, Andrew C, Hughes, Christopher C W
Publicado 2012

Regulation of Partial and Reversible Endothelial-to-Mesenchymal Transition in Angiogenesis

por Fang, Jennifer S., Hultgren, Nan W., Hughes, Christopher C. W.
Publicado 2021

GNAQ mutations drive port wine birthmark-associated Sturge-Weber syndrome: A review of pathobiology, therapies, and current models

por Van Trigt, William K., Kelly, Kristen M., Hughes, Christopher C. W.
Publicado 2022

Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks

por Curtis, Matthew B., Kelly, Natalie, Hughes, Christopher C. W., George, Steven C.
Publicado 2022

The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

por Newman, Andrew C., Nakatsu, Martin N., Chou, Wayne, Gershon, Paul D., Hughes, Christopher C. W.
Publicado 2011

Exosomes as a Source of Biomarkers for Gastrointestinal Cancers

por Yu, Jingjing, Ostowari, Arsha, Gonda, Amber, Mashayekhi, Kiarash, Dayyani, Farshid, Hughes, Christopher C. W., Senthil, Maheswari
Publicado 2023

Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced b...

por Gray, Michael J., Gong, Jian, Hatch, Michaela M. S., Nguyen, Van, Hughes, Christopher C. W., Hutchins, Jeff T., Freimark, Bruce D.
Publicado 2016

Integration of the β-Catenin-Dependent Wnt Pathway with Integrin Signaling through the Adaptor Molecule Grb2

por Crampton, Steve P., Wu, Beibei, Park, Edward J., Kim, Jai-Hyun, Solomon, Candice, Waterman, Marian L., Hughes, Christopher C. W.
Publicado 2009

A modular microfluidic system based on a multilayered configuration to generate large-scale perfusable microvascular networks

por Yue, Tao, Zhao, Da, Phan, Duc T. T., Wang, Xiaolin, Park, Joshua Jonghyun, Biviji, Zayn, Hughes, Christopher C. W., Lee, Abraham P.
Publicado 2021

Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions

por Faal, Tannaz, Phan, Duc T.T., Davtyan, Hayk, Scarfone, Vanessa M., Varady, Erika, Blurton-Jones, Mathew, Hughes, Christopher C.W., Inlay, Matthew A.
Publicado 2019

Adoptive T-Cell Therapy in Advanced Colorectal Cancer: A Systematic Review

por Juat, Damie J, Hachey, Stephanie J, Billimek, John, Del Rosario, Michael P, Nelson, Edward L, Hughes, Christopher C W, Zell, Jason A
Publicado 2022

3D microtumors in vitro supported by perfused vascular networks

por Sobrino, Agua, Phan, Duc T. T., Datta, Rupsa, Wang, Xiaolin, Hachey, Stephanie J., Romero-López, Mónica, Gratton, Enrico, Lee, Abraham P., George, Steven C., Hughes, Christopher C. W.
Publicado 2016

A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease

por Hachey, Stephanie J., Sobrino, Agua, Lee, John G., Jafari, Mehraneh D., Klempner, Samuel J., Puttock, Eric J., Edwards, Robert A., Lowengrub, John S., Waterman, Marian L., Zell, Jason A., Hughes, Christopher C.W.
Publicado 2023

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia

por Faughnan, Marie E., Gossage, James R., Chakinala, Murali M., Oh, S. Paul, Kasthuri, Raj, Hughes, Christopher C. W., McWilliams, Justin P., Parambil, Joseph G., Vozoris, Nicholas, Donaldson, Jill, Paul, Gitanjali, Berry, Pamela, Sprecher, Dennis L.
Publicado 2018

Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis

por Hultgren, Nan W., Fang, Jennifer S., Ziegler, Mary E., Ramirez, Ricardo N., Phan, Duc T. T., Hatch, Michaela M. S., Welch-Reardon, Katrina M., Paniagua, Antonio E., Kim, Lin S., Shon, Nathan N., Williams, David S., Mortazavi, Ali, Hughes, Christopher C. W.
Publicado 2020

Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering

por Arulmoli, Janahan, Wright, Heather J., Phan, Duc T.T., Sheth, Urmi, Que, Richard A., Botten, Giovanni A., Keating, Mark, Botvinick, Elliot L., Pathak, Medha M., Zarembinski, Thomas I., Yanni, Daniel S., Razorenova, Olga V., Hughes, Christopher C.W., Flanagan, Lisa A.
Publicado 2016

Plasma Exosome Gene Signature Differentiates Colon Cancer from Healthy Controls

por Vallejos, Paul A., Gonda, Amber, Yu, Jingjing, Sullivan, Brittany G., Ostowari, Arsha, Kwong, Mei Li, Choi, Audrey, Selleck, Matthew J., Kabagwira, Janviere, Fuller, Ryan N., Gironda, Daniel J., Levine, Edward A., Hughes, Christopher C. W., Wall, Nathan R., Miller, Lance D., Senthil, Maheswari
Publicado 2023

An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy

por Hachey, Stephanie J., Movsesyan, Silva, Nguyen, Quy H., Burton-Sojo, Giselle, Tankazyan, Ani, Wu, Jie, Hoang, Tuyen, Zhao, Da, Wang, Shuxiong, Hatch, Michaela M., Celaya, Elizabeth, Gomez, Samantha, Chen, George T., Davis, Ryan T., Nee, Kevin, Pervolarakis, Nicholas, Lawson, Devon A., Kessenbrock, Kai, Lee, Abraham P., Lowengrub, John, Waterman, Marian L., Hughes, Christopher C. W.
Publicado 2021

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

por Jahid, Sohail, Ortega, Jose A., Vuong, Linh M., Acquistapace, Isabella Maria, Hachey, Stephanie J., Flesher, Jessica L., La Serra, Maria Antonietta, Brindani, Nicoletta, La Sala, Giuseppina, Manigrasso, Jacopo, Arencibia, Jose M., Bertozzi, Sine Mandrup, Summa, Maria, Bertorelli, Rosalia, Armirotti, Andrea, Jin, Rongsheng, Liu, Zheng, Chen, Chi-Fen, Edwards, Robert, Hughes, Christopher C.W., De Vivo, Marco, Ganesan, Anand K.
Publicado 2022