Synthesis and Stereochemical Determination of the Peptide Antibiotic Novo29

por Krumberger, Maj, Li, Xingyue, Kreutzer, Adam G., Peoples, Aaron J., Nitti, Anthony G., Cunningham, Andrew M., Jones, Chelsea R., Achorn, Catherine, Ling, Losee L., Hughes, Dallas E., Nowick, James S.
Publicado 2023

Teixobactin Provides Protection against Inhalation Anthrax in the Rabbit Model

por Lawrence, William S., Peel, Jennifer E., Sivasubramani, Satheesh K., Baze, Wallace B., Whorton, Elbert B., Beasley, David W. C., Comer, Jason E., Hughes, Dallas E., Ling, Losee L., Peterson, Johnny W.
Publicado 2020

Structural studies suggest aggregation as one of the modes of action for teixobactin

por Öster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G., Lewandowski, Józef R.
Publicado 2018

Novel Antimicrobials from Uncultured Bacteria Acting against Mycobacterium tuberculosis

por Quigley, Jeffrey, Peoples, Aaron, Sarybaeva, Asel, Hughes, Dallas, Ghiglieri, Meghan, Achorn, Catherine, Desrosiers, Alysha, Felix, Cintia, Liang, Libang, Malveira, Stephanie, Millett, William, Nitti, Anthony, Tran, Baldwin, Zullo, Ashley, Anklin, Clemens, Spoering, Amy, Ling, Losee Lucy, Lewis, Kim
Publicado 2020

A new antibiotic from an uncultured bacterium binds to an immutable target

por Shukla, Rhythm, Peoples, Aaron J., Ludwig, Kevin C., Maity, Sourav, Derks, Maik G.N., de Benedetti, Stefania, Krueger, Annika M, Vermeulen, Bram J.A., Lavore, Francesca, Honorato, Rodrigo V., Grein, Fabian, Bonvin, Alexandre, Kubitscheck, Ulrich, Breukink, Eefjan, Achorn, Catherine, Nitti, Anthony, Schwalen, Christopher J., Spoering, Amy L., Ling, Losee Lucy, Hughes, Dallas, Lelli, Moreno, Roos, Wouter H., Lewis, Kim, Schneider, Tanja, Weingarth, Markus
Publicado 2023

Teixobactin kills bacteria by a two-pronged attack on the cell envelope

por Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G. N., Jones, Chelsea R., Vermeulen, Bram J. A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A. M., Bonvin, Alexandre M. J. J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus
Publicado 2022