AB298. SPR-25 NLRP3/IL-1β mediates denervation during bladder outlet obstruction in rats

por Lutolf, Robin, Hughes, Francis M., Purves, J. Todd
Publicado 2016

AB279. SPR-06 Fibrosis in the bladder in response to outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β

por Hughes, Francis M., Govada, Vihasa, Sexton, Stephanie, Purves, J. Todd
Publicado 2016

Inflammation triggered by the NLRP3 inflammasome is a critical driver of diabetic bladder dysfunction

por Hughes, Francis M., Odom, Michael R., Cervantes, Anissa, Purves, J.Todd
Publicado 2022

Calcium Pyrophosphate And Monosodium Urate Activate The NLRP3 Inflammasome Within Bladder Urothelium Via Reactive Oxygen Species And TXNIP

por Harper, Shelby N, Leidig, Patrick D, Hughes, Francis M, Jin, Huixia, Purves, J Todd
Publicado 2019

Why Are Some People with Lower Urinary Tract Symptoms (LUTS) Depressed? New Evidence That Peripheral Inflammation in the Bladder Causes Central Inflammation and Mood Disorders

por Hughes, Francis M., Odom, Michael R., Cervantes, Anissa, Livingston, Austin J., Purves, J. Todd
Publicado 2023

AB296. SPR-23 Aberrant bladder reflexes can drive hind limb locomotor activity following complete suprasacral spinal cord injury

por Inouye, Brian M., Brooks, Jillene M., Degoski, Danielle J., Hughes, Francis M., Purves, J. Todd, Fraser, Matthew O.
Publicado 2016

Diabetic bladder dysfunction is associated with bladder inflammation triggered through hyperglycemia, not polyuria

por Inouye, Brian M, Hughes, Francis M, Jin, Huixia, Lütolf, Robin, Potnis, Kunal C, Routh, Jonathan C, Rouse, Douglas C, Foo, Wen-Chi, Purves, J Todd
Publicado 2018

A Highly Polarized Th2 Bladder Response to Infection Promotes Epithelial Repair at the Expense of Preventing New Infections

por Wu, Jianxuan, Hayes, Byron W., Phoenix, Cassandra, Macias, Gustavo Sosa, Miao, Yuxuan, Choi, Hae Woong, Hughes, Francis M., Purves, J. Todd, Reinhardt, R. Lee, Abraham, Soman N.
Publicado 2020