Retinoid Differentiation Therapy for Common Types of Acute Myeloid Leukemia

por Brown, Geoffrey, Hughes, Philip
Publicado 2012

Relativistic Jets: The Common Physics Of AGN, Microquasars And Gamma-ray Bursts

por Hughes, Philip A, Bregman, Joel N
Publicado 2006

Delineation of the distinct inflammatory signaling roles of TAK1 and JAK1/3 in the CIA model of rheumatoid arthritis

por Freeze, Robert, Yang, Kelly W., Haystead, Timothy, Hughes, Philip, Scarneo, Scott
Publicado 2023

Differentiation and Cell Survival of Myeloid Leukemia Cells

por Studzinski, George P., Brown, Geoffrey, Danilenko, Michael, Hughes, Philip, Marcinkowska, Ewa
Publicado 2012

Decontamination and Management of Contaminated Hair following a CBRN or HazMat Incident

por Matar, Hazem, Pinhal, Andreia, Amer, Nevine, Barrett, Mark, Thomas, Elliot, Hughes, Philip, Larner, Joanne, Chilcott, Robert P
Publicado 2019

Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer

por Crouch, Brian T., Gallagher, Jennifer, Wang, Roujia, Duer, Joy, Hall, Allison, Soo, Mary Scott, Hughes, Philip, Haystead, Timothy, Ramanujam, Nirmala
Publicado 2019

TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades

por Scarneo, Scott A., Yang, Kelly W., Roques, Jose R., Dai, Alanna, Eibschutz, Liesl S., Hughes, Philip, Haystead, Timothy A.J.
Publicado 2020

Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion

por Scarneo, Scott A., Mansourati, Antoine, Eibschutz, Liesl S., Totzke, Juliane, Roques, Jose R., Loiselle, David, Carlson, David, Hughes, Philip, Haystead, Timothy A. J.
Publicado 2018

Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice

por Scarneo, Scott A., Eibschutz, Liesl S., Bendele, Phillip J., Yang, Kelly W., Totzke, Juliane, Hughes, Philip, Fox, David A., Haystead, Timothy A. J.
Publicado 2019

Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens

por Crouch, Brian, Murphy, Helen, Belonwu, Stella, Martinez, Amy, Gallagher, Jennifer, Hall, Allison, Soo, Mary Scott, Lee, Marianne, Hughes, Philip, Haystead, Timothy, Ramanujam, Nirmala
Publicado 2017

Atmospheric circulation over Europe during the Younger Dryas

por Rea, Brice R., Pellitero, Ramón, Spagnolo, Matteo, Hughes, Philip, Ivy-Ochs, Susan, Renssen, Hans, Ribolini, Adriano, Bakke, Jostein, Lukas, Sven, Braithwaite, Roger J.
Publicado 2020

A Non-Invasive Deep Photoablation Technique to Inhibit DCIS Progression and Induce Antitumor Immunity

por Kaneko, Kensuke, Nagata, Hiroshi, Yang, Xiao-Yi, Ginzel, Joshua, Hartman, Zachary, Everitt, Jeffrey, Hughes, Philip, Haystead, Timothy, Morse, Michael, Lyerly, Herbert Kim, Osada, Takuya
Publicado 2022

Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis

por Bale, Swarna, Verma, Priyanka, Yalavarthi, Bharath, Scarneo, Scott Arthur, Hughes, Philip, Amin, M. Asif, Tsou, Pei-Suen, Khanna, Dinesh, Haystead, Timothy A.J., Bhattacharyya, Swati, Varga, John
Publicado 2023

Cellular fatty acid synthase is required for late stages of HIV-1 replication

por Kulkarni, Manjusha M., Ratcliff, Annette N., Bhat, Menakshi, Alwarawrah, Yazan, Hughes, Philip, Arcos, Jesus, Loiselle, David, Torrelles, Jordi B., Funderburg, Nicholas T., Haystead, Timothy A., Kwiek, Jesse J.
Publicado 2017

Oral Hsp90 inhibitor SNX-5422 attenuates SARS-CoV-2 replication and dampens inflammation in airway cells

por Goswami, Ria, Russell, Veronica S., Tu, Joshua J., Thomas, Charlene, Hughes, Philip, Kelly, Francine, Langel, Stephanie N., Steppe, Justin, Palmer, Scott M., Haystead, Timothy, Blasi, Maria, Permar, Sallie R.
Publicado 2021

Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect against breast ca...

por Kaneko, Kensuke, Acharya, Chaitanya R, Nagata, Hiroshi, Yang, Xiao, Hartman, Zachary Conrad, Hobeika, Amy, Hughes, Philip F, Haystead, Timothy A J, Morse, Michael A, Lyerly, Herbert Kim, Osada, Takuya
Publicado 2022

Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors

por Kaneko, Kensuke, Osada, Takuya, Morse, Michael A., Gwin, William R., Ginzel, Joshua D., Snyder, Joshua C., Yang, Xiao-Yi, Liu, Cong-Xiao, Diniz, Márcio A., Bodoor, Khaldon, Hughes, Philip F., Haystead, Timothy AJ., Lyerly, H. Kim
Publicado 2020

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

por Woodford, Mark R., Dunn, Diana M., Blanden, Adam R., Capriotti, Dante, Loiselle, David, Prodromou, Chrisostomos, Panaretou, Barry, Hughes, Philip F., Smith, Aaron, Ackerman, Wendi, Haystead, Timothy A., Loh, Stewart N., Bourboulia, Dimitra, Schmidt, Laura S., Marston Linehan, W., Bratslavsky, Gennady, Mollapour, Mehdi
Publicado 2016

Expression of membrane Hsp90 is a molecular signature of T cell activation

por Scarneo, Scott A., Smith, Aaron P., Favret, Jacob, O’Connell, Robert, Pickeral, Joy, Yang, Kelly W., Ferrari, Guido, Loiselle, David R., Hughes, Philip F., Kulkarni, Manjusha M., Gargesha, Madhusudhana, Scott, Bryan, Roy, Debashish, Haynes, Barton F., Kwiek, Jesse J., Haystead, Timothy A. J.
Publicado 2022

HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study

por Osada, Takuya, Crosby, Erika J., Kaneko, Kensuke, Snyder, Joshua C., Ginzel, Joshua D., Acharya, Chaitanya R., Yang, Xiao-Yi, Polascik, Thomas J., Spasojevic, Ivan, Nelson, Rendon C., Hobeika, Amy, Hartman, Zachary C., Neckers, Leonard M., Rogatko, Andre, Hughes, Philip F., Huang, Jiaoti, Morse, Michael A., Haystead, Timothy, Lyerly, H. Kim
Publicado 2022