Secreted Amyloid Precursor Protein Alpha (sAPPα Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes

por Peppercorn, Katie, Kleffmann, Torsten, Hughes, Stephanie M., Tate, Warren P.
Publicado 2023

Deficiency of the Lysosomal Protein CLN5 Alters Lysosomal Function and Movement

por Basak, Indranil, Hansen, Rachel A., Ward, Michael E., Hughes, Stephanie M.
Publicado 2021

RNA-Sequencing Analysis Reveals a Regulatory Role for Transcription Factor Fezf2 in the Mature Motor Cortex

por Clare, Alison J., Wicky, Hollie E., Empson, Ruth M., Hughes, Stephanie M.
Publicado 2017

Transcriptome Profiling of Layer 5 Intratelencephalic Projection Neurons From the Mature Mouse Motor Cortex

por Clare, Alison J., Day, Robert C., Empson, Ruth M., Hughes, Stephanie M.
Publicado 2018

Diversity of layer 5 projection neurons in the mouse motor cortex

por Oswald, Manfred J., Tantirigama, Malinda L. S., Sonntag, Ivo, Hughes, Stephanie M., Empson, Ruth M.
Publicado 2013

CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain

por Mathiesen, Sophie N., Lock, Jasmine L., Schoderboeck, Lucia, Abraham, Wickliffe C., Hughes, Stephanie M.
Publicado 2020

Neuroproteomic Analysis after SARS-CoV-2 Infection Reveals Overrepresented Neurodegeneration Pathways and Disrupted Metabolic Pathways

por Basak, Indranil, Harfoot, Rhodri, Palmer, Jennifer E., Kumar, Abhishek, Quiñones-Mateu, Miguel E., Schweitzer, Lucia, Hughes, Stephanie M.
Publicado 2023

Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms

por Parr-Brownlie, Louise C., Bosch-Bouju, Clémentine, Schoderboeck, Lucia, Sizemore, Rachel J., Abraham, Wickliffe C., Hughes, Stephanie M.
Publicado 2015

Effect of soluble amyloid precursor protein-alpha on adult hippocampal neurogenesis in a mouse model of Alzheimer’s disease

por Ohline, Shane M., Chan, Connie, Schoderboeck, Lucia, Wicky, Hollie E., Tate, Warren P., Hughes, Stephanie M., Abraham, Wickliffe C.
Publicado 2022

Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures

por Dearborn, Joshua T., Nelvagal, Hemanth R., Rensing, Nicholas R., Takahashi, Keigo, Hughes, Stephanie M., Wishart, Thomas M., Cooper, Jonathan D., Wong, Michael, Sands, Mark S.
Publicado 2022

The Tripeptide RER Mimics Secreted Amyloid Precursor Protein-Alpha in Upregulating LTP

por Morrissey, Jodi A., Bigus, Erin, Necarsulmer, Julie C., Srinivasan, Vinay, Peppercorn, Katie, O’Leary, Daniel J., Mockett, Bruce G., Tate, Warren P., Hughes, Stephanie M., Parfitt, Karen D., Abraham, Wickliffe C.
Publicado 2019

Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease

por Tan, Valerie T. Y., Mockett, Bruce G., Ohline, Shane M., Parfitt, Karen D., Wicky, Hollie E., Peppercorn, Katie, Schoderboeck, Lucia, Yahaya, Mohamad Fairuz bin, Tate, Warren P., Hughes, Stephanie M., Abraham, Wickliffe C.
Publicado 2018

Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease

por Cain, Jacob T., Likhite, Shibi, White, Katherine A., Timm, Derek J., Davis, Samantha S., Johnson, Tyler B., Dennys-Rivers, Cassandra N., Rinaldi, Federica, Motti, Dario, Corcoran, Sarah, Morales, Pablo, Pierson, Christopher, Hughes, Stephanie M., Lee, Stella Y., Kaspar, Brian K., Meyer, Kathrin, Weimer, Jill M.
Publicado 2019

Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer’s disease

por Smyth, Leon C. D., Murray, Helen C., Hill, Madison, van Leeuwen, Eve, Highet, Blake, Magon, Nicholas J., Osanlouy, Mahyar, Mathiesen, Sophie N., Mockett, Bruce, Singh-Bains, Malvindar K., Morris, Vanessa K., Clarkson, Andrew N., Curtis, Maurice A., Abraham, Wickliffe C., Hughes, Stephanie M., Faull, Richard L. M., Kettle, Anthony J., Dragunow, Mike, Hampton, Mark B.
Publicado 2022