Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics

por Wadsworth, Marc H., Hughes, Travis K., Shalek, Alex K.
Publicado 2015

Seq-Well: A Portable, Low-Cost Platform for High-Throughput Single-Cell RNA-Seq of Low-Input Samples

por Gierahn, Todd M., Wadsworth, Marc H., Hughes, Travis K., Bryson, Bryan D., Butler, Andrew, Satija, Rahul, Fortune, Sarah, Love, J. Christopher, Shalek, Alex K.
Publicado 2017

Continuous genomic diversification of long polynucleotide fragments drives the emergence of new SARS-CoV-2 variants of concern

por Murugadoss, Karthik, Niesen, Michiel J M, Raghunathan, Bharathwaj, Lenehan, Patrick J, Ghosh, Pritha, Feener, Tyler, Anand, Praveen, Simsek, Safak, Suratekar, Rohit, Hughes, Travis K, Soundararajan, Venky
Publicado 2022

Single-Cell RNA Sequencing Reveals That Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress

por Salazar-Martín, Antonio G., Kalluri, Aditya S., Villanueva, Martin A., Hughes, Travis K., Wadsworth, Marc H., Dao, Tyler T., Balcells, Mercedes, Nezami, Farhad R., Shalek, Alex K., Edelman, Elazer R.
Publicado 2023

A Literature-Derived Knowledge Graph Augments the Interpretation of Single Cell RNA-seq Datasets

por Doddahonnaiah, Deeksha, Lenehan, Patrick J., Hughes, Travis K., Zemmour, David, Garcia-Rivera, Enrique, Venkatakrishnan, A. J., Chilaka, Ramakrishna, Khare, Apoorv, Kasaraneni, Akhil, Garg, Abhinav, Anand, Akash, Barve, Rakesh, Thiagarajan, Viswanathan, Soundararajan, Venky
Publicado 2021

Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies

por Hughes, Travis K., Wadsworth, Marc H., Gierahn, Todd M., Do, Tran, Weiss, David, Andrade, Priscila R., Ma, Feiyang, de Andrade Silva, Bruno J., Shao, Shuai, Tsoi, Lam C., Ordovas-Montanes, Jose, Gudjonsson, Johann E., Modlin, Robert L., Love, J. Christopher, Shalek, Alex K.
Publicado 2020

Allergic inflammatory memory in human respiratory epithelial progenitor cells

por Ordovas-Montanes, Jose, Dwyer, Daniel F., Nyquist, Sarah K., Buchheit, Kathleen M., Vukovic, Marko, Deb, Chaarushena, Wadsworth, Marc H., Hughes, Travis K., Kazer, Samuel W., Yoshimoto, Eri, Cahill, Katherine N., Bhattacharyya, Neil, Katz, Howard R., Berger, Bonnie, Laidlaw, Tanya M., Boyce, Joshua A., Barrett, Nora A., Shalek, Alex K.
Publicado 2018

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

por Mead, Benjamin E., Ordovas-Montanes, Jose, Braun, Alexandra P., Levy, Lauren E., Bhargava, Prerna, Szucs, Matthew J., Ammendolia, Dustin A., MacMullan, Melanie A., Yin, Xiaolei, Hughes, Travis K., Wadsworth, Marc H., Ahmad, Rushdy, Rakoff-Nahoum, Seth, Carr, Steven A., Langer, Robert, Collins, James J., Shalek, Alex K., Karp, Jeffrey M.
Publicado 2018

Prevention of tuberculosis in macaques after intravenous BCG immunization

por Darrah, Patricia A., Zeppa, Joseph J., Maiello, Pauline, Hackney, Joshua A., Wadsworth, Marc H., Hughes, Travis K., Pokkali, Supriya, Swanson, Phillip A., Grant, Nicole L., Rodgers, Mark A., Kamath, Megha, Causgrove, Chelsea M., Laddy, Dominick J., Bonavia, Aurelio, Casimiro, Danilo, Lin, Philana Ling, Klein, Edwin, White, Alexander G., Scanga, Charles A., Shalek, Alex K., Roederer, Mario, Flynn, JoAnne L., Seder, Robert A.
Publicado 2020

Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics

por Kotliar, Dylan, Lin, Aaron E., Logue, James, Hughes, Travis K., Khoury, Nadine M., Raju, Siddharth S., Wadsworth, Marc H., Chen, Han, Kurtz, Jonathan R., Dighero-Kemp, Bonnie, Bjornson, Zach B., Mukherjee, Nilanjan, Sellers, Brian A., Tran, Nancy, Bauer, Matthew R., Adams, Gordon C., Adams, Ricky, Rinn, John L., Melé, Marta, Schaffner, Stephen F., Nolan, Garry P., Barnes, Kayla G., Hensley, Lisa E., McIlwain, David R., Shalek, Alex K., Sabeti, Pardis C., Bennett, Richard S.
Publicado 2020

Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation

por Baßler, Kevin, Fujii, Wataru, Kapellos, Theodore S., Dudkin, Erika, Reusch, Nico, Horne, Ari, Reiz, Benedikt, Luecken, Malte D., Osei-Sarpong, Collins, Warnat-Herresthal, Stefanie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Wagner, Allon, Günther, Patrick, Pizarro, Carmen, Schreiber, Tina, Knoll, Rainer, Holsten, Lisa, Kröger, Charlotte, De Domenico, Elena, Becker, Matthias, Händler, Kristian, Wohnhaas, Christian T., Baumgartner, Florian, Köhler, Meike, Theis, Heidi, Kraut, Michael, Wadsworth, Marc H., Hughes, Travis K., Ferreira, Humberto J., Hinkley, Emily, Kaltheuner, Ines H., Geyer, Matthias, Thiele, Christoph, Shalek, Alex K., Feißt, Andreas, Thomas, Daniel, Dickten, Henning, Beyer, Marc, Baum, Patrick, Yosef, Nir, Aschenbrenner, Anna C., Ulas, Thomas, Hasenauer, Jan, Theis, Fabian J., Skowasch, Dirk, Schultze, Joachim L.
Publicado 2022

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

por Gideon, Hannah P., Hughes, Travis K., Tzouanas, Constantine N., Wadsworth, Marc H., Tu, Ang Andy, Gierahn, Todd M., Peters, Joshua M., Hopkins, Forrest F., Wei, Jun-Rong, Kummerlowe, Conner, Grant, Nicole L., Nargan, Kievershen, Phuah, Jia Yao, Borish, H. Jacob, Maiello, Pauline, White, Alexander G., Winchell, Caylin G., Nyquist, Sarah K., Ganchua, Sharie Keanne C., Myers, Amy, Patel, Kush V., Ameel, Cassaundra L., Cochran, Catherine T., Ibrahim, Samira, Tomko, Jaime A., Frye, Lonnie James, Rosenberg, Jacob M., Shih, Angela, Chao, Michael, Klein, Edwin, Scanga, Charles A., Ordovas-Montanes, Jose, Berger, Bonnie, Mattila, Joshua T., Madansein, Rajhmun, Love, J. Christopher, Lin, Philana Ling, Leslie, Alasdair, Behar, Samuel M., Bryson, Bryan, Flynn, JoAnne L., Fortune, Sarah M., Shalek, Alex K.
Publicado 2022

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

por Ziegler, Carly G.K., Allon, Samuel J., Nyquist, Sarah K., Mbano, Ian M., Miao, Vincent N., Tzouanas, Constantine N., Cao, Yuming, Yousif, Ashraf S., Bals, Julia, Hauser, Blake M., Feldman, Jared, Muus, Christoph, Wadsworth, Marc H., Kazer, Samuel W., Hughes, Travis K., Doran, Benjamin, Gatter, G. James, Vukovic, Marko, Taliaferro, Faith, Mead, Benjamin E., Guo, Zhiru, Wang, Jennifer P., Gras, Delphine, Plaisant, Magali, Ansari, Meshal, Angelidis, Ilias, Adler, Heiko, Sucre, Jennifer M.S., Taylor, Chase J., Lin, Brian, Waghray, Avinash, Mitsialis, Vanessa, Dwyer, Daniel F., Buchheit, Kathleen M., Boyce, Joshua A., Barrett, Nora A., Laidlaw, Tanya M., Carroll, Shaina L., Colonna, Lucrezia, Tkachev, Victor, Peterson, Christopher W., Yu, Alison, Zheng, Hengqi Betty, Gideon, Hannah P., Winchell, Caylin G., Lin, Philana Ling, Bingle, Colin D., Snapper, Scott B., Kropski, Jonathan A., Theis, Fabian J., Schiller, Herbert B., Zaragosi, Laure-Emmanuelle, Barbry, Pascal, Leslie, Alasdair, Kiem, Hans-Peter, Flynn, JoAnne L., Fortune, Sarah M., Berger, Bonnie, Finberg, Robert W., Kean, Leslie S., Garber, Manuel, Schmidt, Aaron G., Lingwood, Daniel, Shalek, Alex K., Ordovas-Montanes, Jose
Publicado 2020