The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus

por Hughes, Travis, Sawalha, Amr H
Publicado 2011

Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics

por Wadsworth, Marc H., Hughes, Travis K., Shalek, Alex K.
Publicado 2015

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection

por Hughes, Travis S., Wilson, Henry D., de Vera, Ian Mitchelle S., Kojetin, Douglas J.
Publicado 2015

A structural mechanism of nuclear receptor biased agonism

por Nemetchek, Michelle D., Chrisman, Ian M., Rayl, Mariah L., Voss, Andrew H., Hughes, Travis S.
Publicado 2022

973. Single-cell RNA Sequencing Analysis of Zika Virus Infection in Human Stem Cell-Derived Cerebral Organoids

por Ocwieja, Karen, Stanton, Alexandra, Richards, Alexsia, Antonucci, Jenna, Hughes, Travis, Shalek, Alex, Jaenisch, Rudolph, Gehrke, Lee
Publicado 2019

Ligand-binding dynamics rewire cellular signaling via Estrogen Receptor-α

por Srinivasan, Sathish, Nwachukwu, Jerome C., Parent, Alex A., Cavett, Valerie, Nowak, Jason, Hughes, Travis S., Kojetin, Douglas J., Katzenellenbogen, John A., Nettles, Kendall W.
Publicado 2013

Seq-Well: A Portable, Low-Cost Platform for High-Throughput Single-Cell RNA-Seq of Low-Input Samples

por Gierahn, Todd M., Wadsworth, Marc H., Hughes, Travis K., Bryson, Bryan D., Butler, Andrew, Satija, Rahul, Fortune, Sarah, Love, J. Christopher, Shalek, Alex K.
Publicado 2017

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ

por Shang, Jinsai, Brust, Richard, Mosure, Sarah A, Bass, Jared, Munoz-Tello, Paola, Lin, Hua, Hughes, Travis S, Tang, Miru, Ge, Qingfeng, Kamenekca, Theodore M, Kojetin, Douglas J
Publicado 2018

Continuous genomic diversification of long polynucleotide fragments drives the emergence of new SARS-CoV-2 variants of concern

por Murugadoss, Karthik, Niesen, Michiel J M, Raghunathan, Bharathwaj, Lenehan, Patrick J, Ghosh, Pritha, Feener, Tyler, Anand, Praveen, Simsek, Safak, Suratekar, Rohit, Hughes, Travis K, Soundararajan, Venky
Publicado 2022

Single-Cell RNA Sequencing Reveals That Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress

por Salazar-Martín, Antonio G., Kalluri, Aditya S., Villanueva, Martin A., Hughes, Travis K., Wadsworth, Marc H., Dao, Tyler T., Balcells, Mercedes, Nezami, Farhad R., Shalek, Alex K., Edelman, Elazer R.
Publicado 2023

Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ

por Heidari, Zahra, Chrisman, Ian M., Nemetchek, Michelle D., Novick, Scott J., Blayo, Anne-Laure, Patton, Trey, Mendes, Desiree E., Diaz, Philippe, Kamenecka, Theodore M., Griffin, Patrick R., Hughes, Travis S.
Publicado 2019

An alternate binding site for PPARγ ligands

por Hughes, Travis S., Giri, Pankaj Kumar, de Vera, Ian Mitchelle S., Marciano, David P., Kuruvilla, Dana S., Shin, Youseung, Blayo, Anne-Laure, Kamenecka, Theodore M., Burris, Thomas P., Griffin, Patrick R., Kojetin, Douglas J.
Publicado 2014

A Literature-Derived Knowledge Graph Augments the Interpretation of Single Cell RNA-seq Datasets

por Doddahonnaiah, Deeksha, Lenehan, Patrick J., Hughes, Travis K., Zemmour, David, Garcia-Rivera, Enrique, Venkatakrishnan, A. J., Chilaka, Ramakrishna, Khare, Apoorv, Kasaraneni, Akhil, Garg, Abhinav, Anand, Akash, Barve, Rakesh, Thiagarajan, Viswanathan, Soundararajan, Venky
Publicado 2021

A structural mechanism for directing corepressor-selective inverse agonism of PPARγ

por Brust, Richard, Shang, Jinsai, Fuhrmann, Jakob, Mosure, Sarah A., Bass, Jared, Cano, Andrew, Heidari, Zahra, Chrisman, Ian M., Nemetchek, Michelle D., Blayo, Anne-Laure, Griffin, Patrick R., Kamenecka, Theodore M., Hughes, Travis S., Kojetin, Douglas J.
Publicado 2018

Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain: Harnessing innate immunity to enhance gene therapy

por Sloane, Evan, Langer, Steve, Jekich, Brian, Mahoney, John, Hughes, Travis, Frank, Matthew, Seibert, Whitney, Huberty, Garth, Coats, Benjamen, Harrison, Jackie, Klinman, Dennis, Poole, Steven, Maier, Steven, Johnson, Kirk, Chavez, Ray, Watkins, Linda, Leinwand, Leslie, Milligan, Erin
Publicado 2009

Mapping each pre-existing condition’s association to short-term and long-term COVID-19 complications

por Venkatakrishnan, A. J., Pawlowski, Colin, Zemmour, David, Hughes, Travis, Anand, Akash, Berner, Gabriela, Kayal, Nikhil, Puranik, Arjun, Conrad, Ian, Bade, Sairam, Barve, Rakesh, Sinha, Purushottam, O‘Horo, John C., Badley, Andrew D., Halamka, John, Soundararajan, Venky
Publicado 2021

Regulation of Circadian Behavior and Metabolism by Synthetic REV-ERB Agonists

por Solt, Laura A., Wang, Yongjun, Banerjee, Subhashis, Hughes, Travis, Kojetin, Douglas J., Lundasen, Thomas, Shin, Youseung, Liu, Jin, Cameron, Michael D., Noel, Romain, Yoo, Seung-Hee, Takahashi, Joseph S., Butler, Andrew A., Kamenecka, Theodore M., Burris, Thomas P.
Publicado 2012

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

por Kojetin, Douglas J., Matta-Camacho, Edna, Hughes, Travis S., Srinivasan, Sathish, Nwachukwu, Jerome C., Cavett, Valerie, Nowak, Jason, Chalmers, Michael J., Marciano, David P., Kamenecka, Theodore M., Shulman, Andrew I., Rance, Mark, Griffin, Patrick R., Bruning, John B., Nettles, Kendall W.
Publicado 2015

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

por Nwachukwu, Jerome C, Srinivasan, Sathish, Bruno, Nelson E, Parent, Alexander A, Hughes, Travis S, Pollock, Julie A, Gjyshi, Olsi, Cavett, Valerie, Nowak, Jason, Garcia-Ordonez, Ruben D, Houtman, René, Griffin, Patrick R, Kojetin, Douglas J, Katzenellenbogen, John A, Conkright, Michael D, Nettles, Kendall W
Publicado 2014

Pharmacological Repression of PPARγ Promotes Osteogenesis

por Marciano, David P., Kuruvilla, Dana S., Boregowda, Siddaraju V., Asteian, Alice, Hughes, Travis S., Garcia-Ordonez, Ruben, Corzo, Cesar A., Khan, Tanya M., Novick, Scott J., Park, HaJeung, Kojetin, Douglas J., Phinney, Donald G., Bruning, John B., Kamenecka, Theodore M., Griffin, Patrick R.
Publicado 2015