Inactivation of chronic wasting disease prions using sodium hypochlorite

por Williams, Katie, Hughson, Andrew G., Chesebro, Bruce, Race, Brent
Publicado 2019

Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice

por Chesebro, Bruce, Striebel, James, Rangel, Alejandra, Phillips, Katie, Hughson, Andrew, Caughey, Byron, Race, Brent
Publicado 2015

Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein

por Race, Brent, Baune, Chase, Williams, Katie, Striebel, James F., Hughson, Andrew G., Chesebro, Bruce
Publicado 2022

Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid

por Orrú, Christina D., Groveman, Bradley R., Hughson, Andrew G., Zanusso, Gianluigi, Coulthart, Michael B., Caughey, Byron
Publicado 2015

Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein

por Race, Brent, Williams, Katie, Hughson, Andrew G., Jansen, Casper, Parchi, Piero, Rozemuller, Annemieke J. M., Chesebro, Bruce
Publicado 2018

Efficacy of Wex-cide 128 disinfectant against multiple prion strains

por Baune, Chase, Groveman, Bradley R., Hughson, Andrew G., Thomas, Tina, Twardoski, Barry, Priola, Suzette, Chesebro, Bruce, Race, Brent
Publicado 2023

Reduction of Chronic Wasting Disease Prion Seeding Activity following Digestion by Mountain Lions

por Baune, Chase, Wolfe, Lisa L., Schott, Kristen C., Griffin, Karen A., Hughson, Andrew G., Miller, Michael W., Race, Brent
Publicado 2021

Sporadic Creutzfeldt–Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice

por Groveman, Bradley R., Race, Brent, Foliaki, Simote T., Williams, Katie, Hughson, Andrew G., Baune, Chase, Zanusso, Gianluigi, Haigh, Cathryn L.
Publicado 2023

Factors That Improve RT-QuIC Detection of Prion Seeding Activity

por Orrú, Christina D., Hughson, Andrew G., Groveman, Bradley R., Campbell, Katrina J., Anson, Kelsie J., Manca, Matteo, Kraus, Allison, Caughey, Byron
Publicado 2016

Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

por Orrú, Christina D., Groveman, Bradley R., Raymond, Lynne D., Hughson, Andrew G., Nonno, Romolo, Zou, Wenquan, Ghetti, Bernardino, Gambetti, Pierluigi, Caughey, Byron
Publicado 2015

Correction: Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

por Orrú, Christina D., Groveman, Bradley R., Raymond, Lynne D., Hughson, Andrew G., Nonno, Romolo, Zou, Wenquan, Ghetti, Bernardino, Gambetti, Pierluigi, Caughey, Byron
Publicado 2015

Prion Seeding Activities of Mouse Scrapie Strains with Divergent PrP(Sc) Protease Sensitivities and Amyloid Plaque Content Using RT-QuIC and eQuIC

por Vascellari, Sarah, Orrù, Christina D., Hughson, Andrew G., King, Declan, Barron, Rona, Wilham, Jason M., Baron, Gerald S., Race, Brent, Pani, Alessandra, Caughey, Byron
Publicado 2012

Extended and direct evaluation of RT‐QuIC assays for Creutzfeldt‐Jakob disease diagnosis

por Groveman, Bradley R., Orrú, Christina D., Hughson, Andrew G., Bongianni, Matilde, Fiorini, Michele, Imperiale, Daniele, Ladogana, Anna, Pocchiari, Maurizio, Zanusso, Gianluigi, Caughey, Byron
Publicado 2016

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions

por Franceschini, Alessia, Baiardi, Simone, Hughson, Andrew G., McKenzie, Neil, Moda, Fabio, Rossi, Marcello, Capellari, Sabina, Green, Alison, Giaccone, Giorgio, Caughey, Byron, Parchi, Piero
Publicado 2017

Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease

por Groveman, Bradley R., Ferreira, Natalia C., Foliaki, Simote T., Walters, Ryan O., Winkler, Clayton W., Race, Brent, Hughson, Andrew G., Zanusso, Gianluigi, Haigh, Cathryn L.
Publicado 2021

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

por Groveman, Bradley R., Orrù, Christina D., Hughson, Andrew G., Raymond, Lynne D., Zanusso, Gianluigi, Ghetti, Bernardino, Campbell, Katrina J., Safar, Jiri, Galasko, Douglas, Caughey, Byron
Publicado 2018

Correction to: Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

por Groveman, Bradley R., Orrù, Christina D., Hughson, Andrew G., Raymond, Lynne D., Zanusso, Gianluigi, Ghetti, Bernardino, Campbell, Katrina J., Safar, Jiri, Galasko, Douglas, Caughey, Byron
Publicado 2020

Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

por Hoyt, Forrest, Alam, Parvez, Artikis, Efrosini, Schwartz, Cindi L., Hughson, Andrew G., Race, Brent, Baune, Chase, Raymond, Gregory J., Baron, Gerald S., Kraus, Allison, Caughey, Byron
Publicado 2022

Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates

por Groveman, Bradley R., Raymond, Gregory J., Campbell, Katrina J., Race, Brent, Raymond, Lynne D., Hughson, Andrew G., Orrú, Christina D., Kraus, Allison, Phillips, Katie, Caughey, Byron
Publicado 2017

Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

por Hall, Sara, Orrù, Christina D., Serrano, Geidy E., Galasko, Douglas, Hughson, Andrew G., Groveman, Bradley R., Adler, Charles H., Beach, Thomas G., Caughey, Byron, Hansson, Oskar
Publicado 2022