Adult Gene Therapy for Epilepsy in a Model of Angelman Syndrome: Hope or Hype?

por Huguenard, John R.
Publicado 2023

Perspective: Is Cortical Hyperexcitability the Only Path to Generalized Absence Epilepsy?

por Huguenard, John R.
Publicado 2020

Catching a wave

por Fogerson, P Michelle, Huguenard, John R
Publicado 2016

Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy

por Ferguson, Brielle, Glick, Cameron, Huguenard, John R
Publicado 2023

LSPS/Optogenetics to Improve Synaptic Connectivity Mapping: Unmasking the Role of Basket Cell-Mediated Feedforward Inhibition

por Brill, Julia, Mattis, Joanna, Deisseroth, Karl, Huguenard, John R.
Publicado 2016

Spatially Reciprocal Inhibition of Inhibition within a Stimulus Selection Network in the Avian Midbrain

por Goddard, C. Alex, Mysore, Shreesh P., Bryant, Astra S., Huguenard, John R., Knudsen, Eric I.
Publicado 2014

Desynchronization of Neocortical Networks by Asynchronous Release of GABA at Autaptic and Synaptic Contacts from Fast-Spiking Interneurons

por Manseau, Frédéric, Marinelli, Silvia, Méndez, Pablo, Schwaller, Beat, Prince, David A., Huguenard, John R., Bacci, Alberto
Publicado 2010

Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

por Elleman, Anna V., Devienne, Gabrielle, Makinson, Christopher D., Haynes, Allison L., Huguenard, John R., Du Bois, J.
Publicado 2021

Author Correction: Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

por Elleman, Anna V., Devienne, Gabrielle, Makinson, Christopher D., Haynes, Allison L., Huguenard, John R., Du Bois, J.
Publicado 2022

Closed-loop optogenetic control of thalamus as a new tool to interrupt seizures after cortical injury

por Paz, Jeanne T., Davidson, Thomas J., Frechette, Eric S., Delord, Bruno, Parada, Isabel, Peng, Kathy, Deisseroth, Karl, Huguenard, John R.
Publicado 2012

Nonlinearities between inhibition and T-type calcium channel activity bidirectionally regulate thalamic oscillations

por Lu, Adam C, Lee, Christine Kyuyoung, Kleiman-Weiner, Max, Truong, Brian, Wang, Megan, Huguenard, John R, Beenhakker, Mark P
Publicado 2020

Differentiation and Maturation of Oligodendrocytes in Human Three-Dimensional Neural Cultures

por Marton, Rebecca M., Miura, Yuki, Sloan, Steven A., Li, Qingyun, Revah, Omer, Levy, Rebecca J., Huguenard, John R., Pașca, Sergiu P.
Publicado 2019

Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4

por Beyer, Barbara, Deleuze, Charlotte, Letts, Verity A., Mahaffey, Connie L., Boumil, Rebecca M., Lew, Timothy A., Huguenard, John R., Frankel, Wayne N.
Publicado 2008

Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons

por Ha, Huong T. T., Leal-Ortiz, Sergio, Lalwani, Kriti, Kiyonaka, Shigeki, Hamachi, Itaru, Mysore, Shreesh P., Montgomery, Johanna M., Garner, Craig C., Huguenard, John R., Kim, Sally A.
Publicado 2018

A CMOS-based highly scalable flexible neural electrode interface

por Zhao, Eric T., Hull, Jacob M., Mintz Hemed, Nofar, Uluşan, Hasan, Bartram, Julian, Zhang, Anqi, Wang, Pingyu, Pham, Albert, Ronchi, Silvia, Huguenard, John R., Hierlemann, Andreas, Melosh, Nicholas A.
Publicado 2023

Maladaptive myelination promotes generalized epilepsy progression

por Knowles, Juliet K., Xu, Haojun, Soane, Caroline, Batra, Ankita, Saucedo, Tristan, Frost, Eleanor, Tam, Lydia T., Fraga, Danielle, Ni, Lijun, Villar, Katlin, Talmi, Sydney, Huguenard, John R., Monje, Michelle
Publicado 2022

Long Term Maturation of Human Cortical Organoids Matches Key Early Postnatal Transitions

por Gordon, Aaron, Yoon, Se-Jin, Tran, Stephen S., Makinson, Christopher D., Park, Jin Young, Andersen, Jimena, Valencia, Alfredo M., Horvath, Steve, Xiao, Xinshu, Huguenard, John R., Pașca, Sergiu P., Geschwind, Daniel H.
Publicado 2021

Loss of Rai1 enhances hippocampal excitability and epileptogenesis in mouse models of Smith–Magenis syndrome

por Chang, Ya-Ting, Kowalczyk, Max, Fogerson, P. Michelle, Lee, Yu-Ju, Haque, Minza, Adams, Eliza L., Wang, David C., DeNardo, Laura A., Tessier-Lavigne, Marc, Huguenard, John R., Luo, Liqun, Huang, Wei-Hsiang
Publicado 2022

Reliability of human 3D cortical organoid generation

por Yoon, Se-Jin, Elahi, Lubayna S., Pașca, Anca M., Marton, Rebecca M., Gordon, Aaron, Revah, Omer, Miura, Yuki, Walczak, Elisabeth M., Holdgate, Gwendolyn M., Fan, H. Christina, Huguenard, John R., Geschwind, Daniel H., Pașca, Sergiu P.
Publicado 2018

Assembly of functionally integrated human forebrain spheroids

por Birey, Fikri, Andersen, Jimena, Makinson, Christopher D., Islam, Saiful, Wei, Wu, Huber, Nina, Fan, H. Christina, Cordes Metzler, Kimberly R., Panagiotakos, Georgia, Thom, Nicholas, O’Rourke, Nancy A., Steinmetz, Lars M., Bernstein, Jonathan A., Hallmayer, Joachim, Huguenard, John R., Pașca, Sergiu P.
Publicado 2017