The Path to New Halogenated Quinolines With Enhanced Activities Against Staphylococcus epidermidis

por Huigens, Robert W
Publicado 2018

Chemical Reactions of Indole Alkaloids That Enable Rapid Access to New Scaffolds for Discovery

por Leas, Derek A., Schultz, Daniel C., Huigens, Robert W.
Publicado 2023

Pyrazine and Phenazine Heterocycles: Platforms for Total Synthesis and Drug Discovery

por Huigens, Robert W., Brummel, Beau R., Tenneti, Srinivasarao, Garrison, Aaron T., Xiao, Tao
Publicado 2022

Turning the Tide against Antibiotic Resistance by Evaluating Novel, Halogenated Phenazine, Quinoline, and NH125 Compounds against Ureaplasma Species Clinical Isolates and Mycoplasm...

por Valentine-King, Marissa A., Cisneros, Katherine, James, Margaret O., Huigens, Robert W., Brown, Mary B.
Publicado 2019

Efficacy data of halogenated phenazine and quinoline agents and an NH125 analogue to veterinary mycoplasmas

por Valentine-King, Marissa A., Cisneros, Katherine, James, Margaret O., Huigens, Robert W., Brown, Mary B.
Publicado 2020

A Highly Potent Class of Halogenated Phenazine Antibacterial and Biofilm-Eradicating Agents Accessed Through a Modular Wohl-Aue Synthesis

por Yang, Hongfen, Abouelhassan, Yasmeen, Burch, Gena M., Kallifidas, Dimitris, Huang, Guangtao, Yousaf, Hussain, Jin, Shouguang, Luesch, Hendrik, Huigens, Robert W.
Publicado 2017

Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine’s Biological Activity

por Norwood, Verrill M., Brice-Tutt, Ariana C., Eans, Shainnel O., Stacy, Heather M., Shi, Guqin, Ratnayake, Ranjala, Rocca, James R., Abboud, Khalil A., Li, Chenglong, Luesch, Hendrik, McLaughlin, Jay P., Huigens, Robert W.
Publicado 2020

Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening

por Jenquin, Jana R., O’Brien, Alana P., Poukalov, Kiril, Lu, Yidan, Frias, Jesus A., Shorrock, Hannah K., Richardson, Jared I., Mazdiyasni, Hormoz, Yang, Hongfen, Huigens, Robert W., Boykin, David, Ranum, Laura P.W., Cleary, John Douglas, Wang, Eric T., Berglund, J. Andrew
Publicado 2022

First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival

por Guijarro, Maria V., Kellish, Patrick C., Dib, Peter E., Paciaroni, Nicholas G., Nawab, Akbar, Andring, Jacob, Kulemina, Lidia, Borrero, Nicholas V., Modenutti, Carlos, Feely, Michael, Nasri, Elham, Seifert, Robert P., Luo, Xiaoping, Bennett, Richard L., Shabashvili, Daniil, Licht, Jonathan D., McKenna, Robert, Roitberg, Adrian, Huigens, Robert W., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023