High exposures to bioactivated cyclophosphamide are related to the occurrence of veno-occlusive disease of the liver following high-dose chemotherapy

por de Jonge, M E, Huitema, A D R, Beijnen, J H, Rodenhuis, S
Publicado 2006

Assessment of Performance of Manufacturing Procedures in a Unit for Production of Investigational Anticancer Agents, Using a Mixed Effects Analysis

por van der Schoot, S. C., Nuijen, B., Huitema, A. D. R., Beijnen, J. H.
Publicado 2007

A phase I and pharmacokinetic study of indisulam in combination with carboplatin

por Dittrich, C, Zandvliet, A S, Gneist, M, Huitema, A D R, King, A A J, Wanders, J
Publicado 2007

Evaluation of α(2)-Integrin Expression as a Biomarker for Tumor Growth Inhibition for the Investigational Integrin Inhibitor E7820 in Preclinical and Clinical Studies

por Keizer, Ron J., Funahashi, Y., Semba, T., Wanders, J., Beijnen, J. H., Schellens, J. H. M., Huitema, A. D. R.
Publicado 2011

Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization

por Verheijen, R. B., Swart, L. E., Beijnen, J. H., Schellens, J. H. M., Huitema, A. D. R., Steeghs, N.
Publicado 2017

Pharmacodynamic modeling of adverse effects of anti-cancer drug treatment

por de Vries Schultink, A. H. M., Suleiman, A. A., Schellens, J. H. M., Beijnen, J. H., Huitema, A. D. R.
Publicado 2016

Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma: A pharmacokinetic–pharmacodynamic analysis from the IELSG no. 20 trial

por Joerger, M, Huitema, A D R, Krähenbühl, S, Schellens, J H M, Cerny, T, Reni, M, Zucca, E, Cavalli, F, Ferreri, A J M
Publicado 2010

Pharmacokinetics of oseltamivir carboxylate in critically ill patients: each patient is unique

por Kromdijk, W., Sikma, M. A., van den Broek, M. P. H., Beijnen, J. H., Huitema, A. D. R., de Lange, D. W.
Publicado 2013

Deep learning body-composition analysis of clinically acquired CT-scans estimates creatinine excretion with high accuracy in patients and healthy individuals

por Pieters, Tobias T., Veldhuis, W. B., Moeskops, P., de Vos, B. D., Verhaar, M. C., Haitjema, S., Huitema, A. D. R., Rookmaaker, M. B.
Publicado 2022

Aminoglycoside- and glycopeptide-induced ototoxicity in children: a systematic review

por Diepstraten, F A, Hoetink, A E, van Grotel, M, Huitema, A D R, Stokroos, R J, van den Heuvel-Eibrink, M M, Meijer, A J M
Publicado 2021

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs

por Janssen, J. M., Damoiseaux, D., van Hasselt, J. G. C., Amant, F. C. H., van Calsteren, K., Beijnen, J. H., Huitema, A. D. R., Dorlo, T. P. C.
Publicado 2023

A novel self-microemulsifying formulation of paclitaxel for oral administration to patients with advanced cancer

por Veltkamp, S A, Thijssen, B, Garrigue, J S, Lambert, G, Lallemand, F, Binlich, F, Huitema, A D R, Nuijen, B, Nol, A, Beijnen, J H, Schellens, J H M
Publicado 2006

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of (68)Ga-DOTATATE in patients without neuroendocrine tumors

por Siebinga, H., de Wit-van der Veen, B. J., Beijnen, J. H., Stokkel, M. P. M., Dorlo, T. P. C., Huitema, A. D. R., Hendrikx, J. J. M. A.
Publicado 2021

Phase II and pharmacological study of oral paclitaxel (Paxoral) plus ciclosporin in anthracycline-pretreated metastatic breast cancer

por Helgason, H H, Kruijtzer, C M F, Huitema, A D R, Marcus, S G, ten Bokkel Huinink, W W, Schot, M E, Schornagel, J H, Beijnen, J H, Schellens, J H M
Publicado 2006

A dose-escalation study of indisulam in combination with capecitabine (Xeloda) in patients with solid tumours

por Siegel-Lakhai, W S, Zandvliet, A S, Huitema, A D R, Tibben, M M, Milano, G, Girre, V, Diéras, V, King, A, Richmond, E, Wanders, J, Beijnen, J H, Schellens, J H M
Publicado 2008

Monitoring of platinum surface contamination in seven Dutch hospital pharmacies using inductively coupled plasma mass spectrometry

por Brouwers, E. E. M., Huitema, A. D. R., Bakker, E. N., Douma, J. W., Schimmel, K. J. M., van Weringh, G., de Wolf, P. J., Schellens, J. H. M., Beijnen, J. H.
Publicado 2007

A real or apparent decrease in glomerular filtration rate in patients using olaparib?

por Bruin, M. A. C., Korse, C. M., van Wijnen, B., de Jong, V. M. T., Linn, S. C., van Triest, B., Rosing, H., Beijnen, J. H., van den Broek, D., Huitema, A. D. R.
Publicado 2020

Phase I and pharmacological trial of lapatinib in combination with gemcitabine in patients with advanced breast cancer

por van der Noll, R., Smit, W. M., Wymenga, A. N. M., Boss, D. S., Grob, M., Huitema, A. D. R., Rosing, H., Tibben, M. M., Keessen, M., Rehorst, H., Beijnen, J. H., Schellens, J. H. M.
Publicado 2015

Efficacy and toxicity of vemurafenib and cobimetinib in relation to plasma concentrations, after administration via feeding tube in patients with BRAF-mutated thyroid cancer: a cas...

por van Berge Henegouwen, J. M., van der Wijngaart, H., Zeverijn, L. J., Hoes, L. R., Meertens, M., Huitema, A. D. R., Devriese, L. A., Labots, M., Verheul, H. M. W., Voest, E. E., Gelderblom, H.
Publicado 2022

Phenotypic factors associated with amisulpride‐induced weight gain in first‐episode psychosis patients (from the OPTiMiSE cohort)

por Pandit, R., Cianci, D., ter Hark, S. E., Winter‐van Rossum, I., Ebdrup, B. H., Broberg, B. V., Garcia‐Portilla, M. P., Bobes, J., Vinkers, C. H., Kahn, R. S., Guloksuz, S., Huitema, A. D. R., Luykx, J. J.
Publicado 2019