Herpesvirus Vectors in Gene Therapy

por Hukkanen, Veijo
Publicado 2010

Human lactoferrin but not lysozyme neutralizes HSV-1 and inhibits HSV-1 replication and cell-to-cell spread

por Välimaa, Hannamari, Tenovuo, Jorma, Waris, Matti, Hukkanen, Veijo
Publicado 2009

The combined effects of irradiation and herpes simplex virus type 1 infection on an immortal gingival cell line

por Turunen, Aaro, Hukkanen, Veijo, Nygårdas, Michaela, Kulmala, Jarmo, Syrjänen, Stina
Publicado 2014

Herpes Simplex Virus Seroprevalence among Pregnant Finnish Women and Their Spouses—A Six-Year Follow-Up Cohort Study

por Laakso, Johanna, Vuorinen, Tytti, Rautava, Jaana, Kero, Katja, Syrjänen, Stina, Hukkanen, Veijo
Publicado 2022

Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA

por Kari, Ilkka, Syrjänen, Stina, Johansson, Bo, Peri, Piritta, He, Bin, Roizman, Bernard, Hukkanen, Veijo
Publicado 2007

Enzymatically Produced Pools of Canonical and Dicer-Substrate siRNA Molecules Display Comparable Gene Silencing and Antiviral Activities against Herpes Simplex Virus

por Romanovskaya, Alesia, Paavilainen, Henrik, Nygårdas, Michaela, Bamford, Dennis H., Hukkanen, Veijo, Poranen, Minna M.
Publicado 2012

Native RNA Purification Method for Small RNA Molecules Based on Asymmetrical Flow Field-Flow Fractionation

por Levanova, Alesia A., Lampi, Mirka, Kalke, Kiira, Hukkanen, Veijo, Poranen, Minna M., Eskelin, Katri
Publicado 2022

A Herpes Simplex Virus-Derived Replicative Vector Expressing LIF Limits Experimental Demyelinating Disease and Modulates Autoimmunity

por Nygårdas, Michaela, Paavilainen, Henrik, Müther, Nadine, Nagel, Claus-Henning, Röyttä, Matias, Sodeik, Beate, Hukkanen, Veijo
Publicado 2013

The ERK-1 function is required for HSV-1-mediated G1/S progression in HEP-2 cells and contributes to virus growth

por Colao, Ivana, Pennisi, Rosamaria, Venuti, Assunta, Nygårdas, Michaela, Heikkilä, Outi, Hukkanen, Veijo, Sciortino, Maria Teresa
Publicado 2017

Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy

por Palomäki, Jussi, Kalke, Kiira, Orpana, Julius, Lund, Liisa, Frejborg, Fanny, Paavilainen, Henrik, Järveläinen, Hannu, Hukkanen, Veijo
Publicado 2023

Herpes Simplex Virus Type 1 Us3 Gene Deletion Influences Toll-like Receptor Responses in Cultured Monocytic Cells

por Peri, Piritta, Mattila, Riikka K, Kantola, Helena, Broberg, Eeva, Karttunen, Heidi S, Waris, Matti, Vuorinen, Tytti, Hukkanen, Veijo
Publicado 2008

The In Vitro Replication, Spread, and Oncolytic Potential of Finnish Circulating Strains of Herpes Simplex Virus Type 1

por Kalke, Kiira, Orpana, Julius, Lasanen, Tuomas, Esparta, Olaya, Lund, Liisa M., Frejborg, Fanny, Vuorinen, Tytti, Paavilainen, Henrik, Hukkanen, Veijo
Publicado 2022

Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells

por Kalke, Kiira, Lund, Liisa M., Nyman, Marie C., Levanova, Alesia A., Urtti, Arto, Poranen, Minna M., Hukkanen, Veijo, Paavilainen, Henrik
Publicado 2022

Comparison of Herpes Simplex Virus 1 Strains Circulating in Finland Demonstrates the Uncoupling of Whole-Genome Relatedness and Phenotypic Outcomes of Viral Infection

por Bowen, Christopher D., Paavilainen, Henrik, Renner, Daniel W., Palomäki, Jussi, Lehtinen, Jenni, Vuorinen, Tytti, Norberg, Peter, Hukkanen, Veijo, Szpara, Moriah L.
Publicado 2019

Enzymatically synthesized 2′-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity

por Levanova, Alesia A., Kalke, Kiira M., Lund, Liisa M., Sipari, Nina, Sadeghi, Mohammadreza, Nyman, Marie C., Paavilainen, Henrik, Hukkanen, Veijo, Poranen, Minna M.
Publicado 2020

Herpes simplex virus 1 induces egress channels through marginalized host chromatin

por Myllys, Markko, Ruokolainen, Visa, Aho, Vesa, Smith, Elizabeth A., Hakanen, Satu, Peri, Piritta, Salvetti, Anna, Timonen, Jussi, Hukkanen, Veijo, Larabell, Carolyn A., Vihinen-Ranta, Maija
Publicado 2016

Chromatin organization regulates viral egress dynamics

por Aho, Vesa, Myllys, Markko, Ruokolainen, Visa, Hakanen, Satu, Mäntylä, Elina, Virtanen, Jori, Hukkanen, Veijo, Kühn, Thomas, Timonen, Jussi, Mattila, Keijo, Larabell, Carolyn A., Vihinen-Ranta, Maija
Publicado 2017

HERQ-9 Is a New Multiplex PCR for Differentiation and Quantification of All Nine Human Herpesviruses

por Pyöriä, Lari, Jokinen, Maija, Toppinen, Mari, Salminen, Henri, Vuorinen, Tytti, Hukkanen, Veijo, Schmotz, Constanze, Elbasani, Endrit, Ojala, Päivi M., Hedman, Klaus, Välimaa, Hannamari, Perdomo, Maria F.
Publicado 2020

Personalized Cancer Vaccine Platform for Clinically Relevant Oncolytic Enveloped Viruses

por Ylösmäki, Erkko, Malorzo, Cristina, Capasso, Cristian, Honkasalo, Oona, Fusciello, Manlio, Martins, Beatriz, Ylösmäki, Leena, Louna, Antti, Feola, Sara, Paavilainen, Henrik, Peltonen, Karita, Hukkanen, Veijo, Viitala, Tapani, Cerullo, Vincenzo
Publicado 2018

Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity

por Kalke, Kiira, Lehtinen, Jenni, Gnjatovic, Jelena, Lund, Liisa M., Nyman, Marie C., Paavilainen, Henrik, Orpana, Julius, Lasanen, Tuomas, Frejborg, Fanny, Levanova, Alesia A., Vuorinen, Tytti, Poranen, Minna M., Hukkanen, Veijo
Publicado 2020