2-Butyl-11-phenyl-5,10-dihydro-1H-benzo[e]imidazo[1,5-a][1,4]diazepine-1,3(2H)-dione

por Nichol, Gary S., Gunawan, Steven, Dietrich, Justin, Hulme, Christopher
Publicado 2010

Crystal structures of N-tert-butyl-3-(4-fluoro­phenyl)-5-oxo-4-[2-(tri­fluoro­meth­oxy)phen­yl]-2,5-di­hydro­furan-2-carboxamide and 4-(2H-1,3-benzodioxol-5-yl)-N-cyclo­hexyl-5-oxo...

por Roberts, Sue A., Martinez-Ariza, Guillermo, Hulme, Christopher
Publicado 2015

The Omnipresence of DYRK1A in Human Diseases

por Deboever, Estelle, Fistrovich, Alessandra, Hulme, Christopher, Dunckley, Travis
Publicado 2022

4-(Piperidin-1-yl)-4H-benzo[b]tetra­zolo[1,5-d][1,4]diazepin-5(6H)-one

por Nichol, Gary S., Xu, Zhigang, Kaiser, Christine E., Hulme, Christopher
Publicado 2010

Synthesis of Diverse Nitrogen-Enriched Heterocyclic Scaffolds Using a Suite of Tunable One-Pot Multicomponent Reactions

por Martinez-Ariza, Guillermo, Ayaz, Muhammad, Medda, Federico, Hulme, Christopher
Publicado 2014

2-Propyl 3,3-dibromo-2-hydroxy­pyrrolidine-1-carboxyl­ate

por Nichol, Gary S., Gunawan, Steven, Xu, Zhigang, Dietrich, Justin, Hulme, Christopher
Publicado 2010

2,4-Diphenyl-6-trifluoro­methyl-2,3-dihydro-1H,5H-pyrrolo­[3,4-c]pyrrole-1,3-dione

por Roberts, Sue A., Martinez-Ariza, Guillermo, Dietrich, Justin, Hulme, Christopher
Publicado 2012

3-(4-Bromo­phen­yl)-1-butyl-5-[1-(2-chloro-6-methyl­phen­yl)-1H-tetra­zol-5-yl]imidazolidine-2,4-dione

por Hall, Gabriel B., Medda, Federico, Roberts, Sue A., Hulme, Christopher
Publicado 2013

DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity

por Zhu, Bangfu, Parsons, Tom, Foley, Christopher, Shaw, Yeng, Dunckley, Travis, Hulme, Christopher, Hodge, James J. L.
Publicado 2022

Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance

por Zhang, Jiantao, Hu, Yanmei, Foley, Christopher, Wang, Yuanxiang, Musharrafieh, Rami, Xu, Shuting, Zhang, Yongtao, Ma, Chunlong, Hulme, Christopher, Wang, Jun
Publicado 2018

Dyrk1 inhibition improves Alzheimer's disease‐like pathology

por Branca, Caterina, Shaw, Darren M., Belfiore, Ramona, Gokhale, Vijay, Shaw, Arthur Y., Foley, Christopher, Smith, Breland, Hulme, Christopher, Dunckley, Travis, Meechoovet, Bessie, Caccamo, Antonella, Oddo, Salvatore
Publicado 2017

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes

por Muñoz-Torrero, Diego, Mangoni, Arduino A., Guillou, Catherine, Collina, Simona, Vanden Eynde, Jean Jacques, Rautio, Jarkko, Keserű, György M., Hulme, Christopher, Chibale, Kelly, Luque, F. Javier, Karaman, Rafik, Gütschow, Michael, Liu, Hong, Ragno, Rino
Publicado 2017

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–2

por Muñoz-Torrero, Diego, Mangoni, Arduino A., Liu, Hong, Hulme, Christopher, Rautio, Jarkko, Karaman, Rafik, de Sousa, Maria Emília, Prokai-Tatrai, Katalin, Sabatier, Jean-Marc, Siciliano, Carlo, Luque, F. Javier, Kokotos, George, Ragno, Rino, Collina, Simona, Guillou, Catherine, Gütschow, Michael, Agrofoglio, Luigi A.
Publicado 2017

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

por Mangoni, Arduino A., Tuccinardi, Tiziano, Collina, Simona, Vanden Eynde, Jean Jacques, Muñoz-Torrero, Diego, Karaman, Rafik, Siciliano, Carlo, de Sousa, Maria Emília, Prokai-Tatrai, Katalin, Rautio, Jarkko, Guillou, Catherine, Gütschow, Michael, Galdiero, Stefania, Liu, Hong, Agrofoglio, Luigi A., Sabatier, Jean-Marc, Hulme, Christopher, Kokotos, George, You, Qidong, Gomes, Paula A. C.
Publicado 2018

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

por Strine, Madison S., Cai, Wesley L., Wei, Jin, Alfajaro, Mia Madel, Filler, Renata B., Biering, Scott B., Sarnik, Sylvia, Chow, Ryan D., Patil, Ajinkya, Cervantes, Kasey S., Collings, Clayton K., DeWeirdt, Peter C., Hanna, Ruth E., Schofield, Kevin, Hulme, Christopher, Konermann, Silvana, Doench, John G., Hsu, Patrick D., Kadoch, Cigall, Yan, Qin, Wilen, Craig B.
Publicado 2023

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–4

por Mangoni, Arduino A, Guillou, Catherine, Vanden Eynde, Jean Jacques, Hulme, Christopher, Jampilek, Josef, Li, Wei, Prokai-Tatrai, Katalin, Rautio, Jarkko, Collina, Simona, Tuccinardi, Tiziano, Sousa, Maria Emília, Sabatier, Jean-Marc, Galdiero, Stefania, Karaman, Rafik, Kokotos, George, Torri, Giangiacomo, Luque, F. Javier, Vasconcelos, M. Helena, Hadjipavlou-Litina, Dimitra, Siciliano, Carlo, Gütschow, Michael, Ragno, Rino, Gomes, Paula A. C., Agrofoglio, Luigi A., Muñoz-Torrero, Diego
Publicado 2018

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–5

por Mangoni, Arduino A., Eynde, Jean Jacques Vanden, Jampilek, Josef, Hadjipavlou-Litina, Dimitra, Liu, Hong, Reynisson, Jóhannes, Sousa, Maria Emília, Gomes, Paula A. C., Prokai-Tatrai, Katalin, Tuccinardi, Tiziano, Sabatier, Jean-Marc, Luque, F. Javier, Rautio, Jarkko, Karaman, Rafik, Vasconcelos, M. Helena, Gemma, Sandra, Galdiero, Stefania, Hulme, Christopher, Collina, Simona, Gütschow, Michael, Kokotos, George, Siciliano, Carlo, Capasso, Raffaele, Agrofoglio, Luigi A., Ragno, Rino, Muñoz-Torrero, Diego
Publicado 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

por Vanden Eynde, Jean Jacques, Mangoni, Arduino A., Rautio, Jarkko, Leprince, Jérôme, Azuma, Yasu-Taka, García-Sosa, Alfonso T., Hulme, Christopher, Jampilek, Josef, Karaman, Rafik, Li, Wei, Gomes, Paula A. C., Hadjipavlou-Litina, Dimitra, Capasso, Raffaele, Geronikaki, Athina, Cerchia, Laura, Sabatier, Jean-Marc, Ragno, Rino, Tuccinardi, Tiziano, Trabocchi, Andrea, Winum, Jean-Yves, Luque, F. Javier, Prokai-Tatrai, Katalin, Spetea, Mariana, Gütschow, Michael, Kosalec, Ivan, Guillou, Catherine, Vasconcelos, M. Helena, Kokotos, George, Rastelli, Giulio, de Sousa, Maria Emília, Manera, Clementina, Gemma, Sandra, Mangani, Stefano, Siciliano, Carlo, Galdiero, Stefania, Liu, Hong, Scott, Peter J. H., de los Ríos, Cristóbal, Agrofoglio, Luigi A., Collina, Simona, Guedes, Rita C., Muñoz-Torrero, Diego
Publicado 2019