A Copine family member, Cpne8, is a candidate quantitative trait gene for prion disease incubation time in mouse

por Lloyd, Sarah E., Maytham, Emma G., Grizenkova, Julia, Hummerich, Holger, Collinge, John
Publicado 2009

Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence

por Kumari, Ruchi, Hummerich, Holger, Shen, Xu, Fischer, Martin, Litovchick, Larisa, Mittnacht, Sibylle, DeCaprio, James A., Jat, Parmjit S.
Publicado 2021

Activation of Nuclear Factor-kappa B signalling promotes cellular senescence

por Rovillain, Emilie, Mansfield, Louise, Caetano, Catia, Alvarez-Fernandez, Monica, Caballero, Otavia L., Medema, Rene H., Hummerich, Holger, Jat, Parmjit S.
Publicado 2011

Sod1 Deficiency Reduces Incubation Time in Mouse Models of Prion Disease

por Akhtar, Shaheen, Grizenkova, Julia, Wenborn, Adam, Hummerich, Holger, Fernandez de Marco, Mar, Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Publicado 2013

Variants of PLCXD3 are not associated with variant or sporadic Creutzfeldt-Jakob disease in a large international study

por Balendra, Rubika, Uphill, James, Collinson, Claire, Druyeh, Ronald, Adamson, Gary, Hummerich, Holger, Zerr, Inga, Gambetti, Pierluigi, Collinge, John, Mead, Simon
Publicado 2016

In vitro screen of prion disease susceptibility genes using the scrapie cell assay

por Brown, Craig A., Schmidt, Christian, Poulter, Mark, Hummerich, Holger, Klöhn, Peter-C., Jat, Parmjit, Mead, Simon, Collinge, John, Lloyd, Sarah E.
Publicado 2014

Genetic Analysis of the Cytoplasmic Dynein Subunit Families

por Pfister, K. Kevin, Shah, Paresh R, Hummerich, Holger, Russ, Andreas, Cotton, James, Annuar, Azlina Ahmad, King, Stephen M, Fisher, Elizabeth M. C
Publicado 2006

DNA methylation analysis of archival lymphoreticular tissues in Creutzfeldt–Jakob disease

por Guntoro, Fernando, Viré, Emmanuelle, Giordani, Chiara, Darwent, Lee, Hummerich, Holger, Linehan, Jacqueline, Sinka, Katy, Jaunmuktane, Zane, Brandner, Sebastian, Collinge, John, Mead, Simon
Publicado 2022

Genetic susceptibility, evolution and the kuru epidemic

por Mead, Simon, Whitfield, Jerome, Poulter, Mark, Shah, Paresh, Uphill, James, Beck, Jonathan, Campbell, Tracy, Al-Dujaily, Huda, Hummerich, Holger, Alpers, Michael P., Collinge, John
Publicado 2008

Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection

por Castro-Seoane, Rocio, Hummerich, Holger, Sweeting, Trevor, Tattum, M. Howard, Linehan, Jacqueline M., Fernandez de Marco, Mar, Brandner, Sebastian, Collinge, John, Klöhn, Peter-Christian
Publicado 2012

HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease

por Lloyd, Sarah E., Maytham, Emma G., Pota, Hirva, Grizenkova, Julia, Molou, Eleni, Uphill, James, Hummerich, Holger, Whitfield, Jerome, Alpers, Michael P., Mead, Simon, Collinge, John
Publicado 2009

Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years

por Rudge, Peter, Jaunmuktane, Zane, Adlard, Peter, Bjurstrom, Nina, Caine, Diana, Lowe, Jessica, Norsworthy, Penny, Hummerich, Holger, Druyeh, Ron, Wadsworth, Jonathan D. F., Brandner, Sebastian, Hyare, Harpreet, Mead, Simon, Collinge, John
Publicado 2015

Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence

por Iannetti, Alessio, Ledoux, Adeline C., Tudhope, Susan J., Sellier, Hélène, Zhao, Bo, Mowla, Sophia, Moore, Adam, Hummerich, Holger, Gewurz, Benjamin E., Cockell, Simon J., Jat, Parmjit S., Willmore, Elaine, Perkins, Neil D.
Publicado 2014

Identification of a gene regulatory network associated with prion replication

por Marbiah, Masue M, Harvey, Anna, West, Billy T, Louzolo, Anais, Banerjee, Priya, Alden, Jack, Grigoriadis, Anita, Hummerich, Holger, Kan, Ho-Man, Cai, Ying, Bloom, George S, Jat, Parmjit, Collinge, John, Klöhn, Peter-Christian
Publicado 2014

Exome Sequencing of 75 Individuals from Multiply Affected Coeliac Families and Large Scale Resequencing Follow Up

por Mistry, Vanisha, Bockett, Nicholas A., Levine, Adam P., Mirza, Muddassar M., Hunt, Karen A., Ciclitira, Paul J., Hummerich, Holger, Neuhausen, Susan L., Simpson, Michael A., Plagnol, Vincent, van Heel, David A.
Publicado 2015

Genetic risk factors for variant Creutzfeldt–Jakob disease: a genome-wide association study

por Mead, Simon, Poulter, Mark, Uphill, James, Beck, John, Whitfield, Jerome, Webb, Thomas EF, Campbell, Tracy, Adamson, Gary, Deriziotis, Pelagia, Tabrizi, Sarah J, Hummerich, Holger, Verzilli, Claudio, Alpers, Michael P, Whittaker, John C, Collinge, John
Publicado 2009

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease

por Holstege, Henne, Hulsman, Marc, Charbonnier, Camille, Grenier-Boley, Benjamin, Quenez, Olivier, Grozeva, Detelina, van Rooij, Jeroen G. J., Sims, Rebecca, Ahmad, Shahzad, Amin, Najaf, Norsworthy, Penny J., Dols-Icardo, Oriol, Hummerich, Holger, Kawalia, Amit, Amouyel, Philippe, Beecham, Gary W., Berr, Claudine, Bis, Joshua C., Boland, Anne, Bossù, Paola, Bouwman, Femke, Bras, Jose, Campion, Dominique, Cochran, J. Nicholas, Daniele, Antonio, Dartigues, Jean-François, Debette, Stéphanie, Deleuze, Jean-François, Denning, Nicola, DeStefano, Anita L., Farrer, Lindsay A., Fernández, Maria Victoria, Fox, Nick C., Galimberti, Daniela, Genin, Emmanuelle, Gille, Johan J. P., Le Guen, Yann, Guerreiro, Rita, Haines, Jonathan L., Holmes, Clive, Ikram, M. Arfan, Ikram, M. Kamran, Jansen, Iris E., Kraaij, Robert, Lathrop, Marc, Lemstra, Afina W., Lleó, Alberto, Luckcuck, Lauren, Mannens, Marcel M. A. M., Marshall, Rachel, Martin, Eden R., Masullo, Carlo, Mayeux, Richard, Mecocci, Patrizia, Meggy, Alun, Mol, Merel O., Morgan, Kevin, Myers, Richard M., Nacmias, Benedetta, Naj, Adam C., Napolioni, Valerio, Pasquier, Florence, Pastor, Pau, Pericak-Vance, Margaret A., Raybould, Rachel, Redon, Richard, Reinders, Marcel J. T., Richard, Anne-Claire, Riedel-Heller, Steffi G., Rivadeneira, Fernando, Rousseau, Stéphane, Ryan, Natalie S., Saad, Salha, Sanchez-Juan, Pascual, Schellenberg, Gerard D., Scheltens, Philip, Schott, Jonathan M., Seripa, Davide, Seshadri, Sudha, Sie, Daoud, Sistermans, Erik A., Sorbi, Sandro, van Spaendonk, Resie, Spalletta, Gianfranco, Tesi, Niccolo’, Tijms, Betty, Uitterlinden, André G., van der Lee, Sven J., Visser, Pieter Jelle, Wagner, Michael, Wallon, David, Wang, Li-San, Zarea, Aline, Clarimon, Jordi, van Swieten, John C., Greicius, Michael D., Yokoyama, Jennifer S., Cruchaga, Carlos, Hardy, John, Ramirez, Alfredo, Mead, Simon, van der Flier, Wiesje M., van Duijn, Cornelia M., Williams, Julie, Nicolas, Gaël, Bellenguez, Céline, Lambert, Jean-Charles
Publicado 2022