Environmental control of Pub1 (NEDD4 family E3 ligase) in Schizosaccharomyces pombe is regulated by TORC2 and Gsk3

por Wang, Tingting, Woodman, Philip, Humphrey, Sean J, Petersen, Janni
Publicado 2022

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

por Sacco, Francesca, Humphrey, Sean J., Cox, Jürgen, Mischnik, Marcel, Schulte, Anke, Klabunde, Thomas, Schäfer, Matthias, Mann, Matthias
Publicado 2016

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

por Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.
Publicado 2013

SnapKin: a snapshot deep learning ensemble for kinase-substrate prediction from phosphoproteomics data

por Xiao, Di, Lin, Michael, Liu, Chunlei, Geddes, Thomas A, Burchfield, James G, Parker, Benjamin L, Humphrey, Sean J, Yang, Pengyi
Publicado 2023

Proteomic Analysis of Human Plasma during Intermittent Fasting

por Harney, Dylan J., Hutchison, Amy T., Hatchwell, Luke, Humphrey, Sean J., James, David E., Hocking, Samantha, Heilbronn, Leonie K., Larance, Mark
Publicado 2019

Correction: Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

por Domanova, Westa, Krycer, James R., Chaudhuri, Rima, Yang, Pengyi, Vafaee, Fatemeh, Fazakerley, Daniel J., Humphrey, Sean J., James, David E., Kuncic, Zdenka
Publicado 2017

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

por Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Publicado 2019

Corrigendum to ‘ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation’ [Molecular Metabolism 25 (2019) p.83–94]

por Stöckli, Jacqueline, Zadoorian, Armella, Cooke, Kristen C., Deshpande, Vinita, Yau, Belinda, Herrmann, Gaia, Kebede, Melkam A., Humphrey, Sean J., James, David E.
Publicado 2021

Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia

por Murray, Heather C., Miller, Kasey, Brzozowski, Joshua S., Kahl, Richard G.S., Smith, Nathan D., Humphrey, Sean J., Dun, Matthew D., Verrills, Nicole M.
Publicado 2023

PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications

por Chaudhuri, Rima, Sadrieh, Arash, Hoffman, Nolan J., Parker, Benjamin L., Humphrey, Sean J., Stöckli, Jacqueline, Hill, Adam P., James, David E., Yang, Jean Yee Hwa
Publicado 2015

A Two-Dimensional Metallacycle Cross-Linked Switchable Polymer for Fast and Highly Efficient Phosphorylated Peptide Enrichment

por Chen, Li-Jun, Humphrey, Sean J., Zhu, Jun-Long, Zhu, Fan-Fan, Wang, Xu-Qing, Wang, Xiang, Wen, Jin, Yang, Hai-Bo, Gale, Philip A.
Publicado 2021

Deep Proteome Profiling of White Adipose Tissue Reveals Marked Conservation and Distinct Features Between Different Anatomical Depots

por Madsen, Søren, Nelson, Marin E., Deshpande, Vinita, Humphrey, Sean J., Cooke, Kristen C., Howell, Anna, Diaz-Vegas, Alexis, Burchfield, James G., Stöckli, Jacqueline, James, David E.
Publicado 2023

A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans

por Halova, Lenka, Cobley, David, Franz-Wachtel, Mirita, Wang, Tingting, Morrison, Kaitlin R., Krug, Karsten, Nalpas, Nicolas, Maček, Boris, Hagan, Iain M., Humphrey, Sean J., Petersen, Janni
Publicado 2021

Transcriptional network dynamics during the progression of pluripotency revealed by integrative statistical learning

por Kim, Hani Jieun, Osteil, Pierre, Humphrey, Sean J, Cinghu, Senthilkumar, Oldfield, Andrew J, Patrick, Ellis, Wilkie, Emilie E, Peng, Guangdun, Suo, Shengbao, Jothi, Raja, Tam, Patrick P L, Yang, Pengyi
Publicado 2020

Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells

por Recasens, Ariadna, Humphrey, Sean J., Ellis, Michael, Hoque, Monira, Abbassi, Ramzi H., Chen, Brianna, Longworth, Mitchell, Needham, Elise J., James, David E., Johns, Terrance G., Day, Bryan W., Kassiou, Michael, Yang, Pengyi, Munoz, Lenka
Publicado 2021

Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate

por Duan, Xiaowen, Norris, Dougall M., Humphrey, Sean J., Yang, Pengyi, Cooke, Kristen C., Bultitude, Will P., Parker, Benjamin L., Conway, Olivia J., Burchfield, James G., Krycer, James R., Brodsky, Frances M., James, David E., Fazakerley, Daniel J.
Publicado 2022

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

por Kearney, Alison L, Norris, Dougall M, Ghomlaghi, Milad, Kin Lok Wong, Martin, Humphrey, Sean J, Carroll, Luke, Yang, Guang, Cooke, Kristen C, Yang, Pengyi, Geddes, Thomas A, Shin, Sungyoung, Fazakerley, Daniel J, Nguyen, Lan K, James, David E, Burchfield, James G
Publicado 2021

A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology

por Diaz-Vegas, Alexis, Norris, Dougall M, Jall-Rogg, Sigrid, Cooke, Kristen C, Conway, Olivia J, Shun-Shion, Amber S, Duan, Xiaowen, Potter, Meg, van Gerwen, Julian, Baird, Harry JM, Humphrey, Sean J, James, David E, Fazakerley, Daniel J, Burchfield, James G
Publicado 2022

MaxDIA enables library-based and library-free data-independent acquisition proteomics

por Sinitcyn, Pavel, Hamzeiy, Hamid, Salinas Soto, Favio, Itzhak, Daniel, McCarthy, Frank, Wichmann, Christoph, Steger, Martin, Ohmayer, Uli, Distler, Ute, Kaspar-Schoenefeld, Stephanie, Prianichnikov, Nikita, Yılmaz, Şule, Rudolph, Jan Daniel, Tenzer, Stefan, Perez-Riverol, Yasset, Nagaraj, Nagarjuna, Humphrey, Sean J., Cox, Jürgen
Publicado 2021

Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance

por Fazakerley, Daniel J., van Gerwen, Julian, Cooke, Kristen C., Duan, Xiaowen, Needham, Elise J., Díaz-Vegas, Alexis, Madsen, Søren, Norris, Dougall M., Shun-Shion, Amber S., Krycer, James R., Burchfield, James G., Yang, Pengyi, Wade, Mark R., Brozinick, Joseph T., James, David E., Humphrey, Sean J.
Publicado 2023