Gaining Mechanistic Insight Into Coproporphyrin I as Endogenous Biomarker for OATP1B‐Mediated Drug–Drug Interactions Using Population Pharmacokinetic Modeling and Simulation

por Barnett, Shelby, Ogungbenro, Kayode, Ménochet, Karelle, Shen, Hong, Lai, Yurong, Humphreys, W. Griffith, Galetin, Aleksandra
Publicado 2018

Lysosomal P-gp-MDR1 Confers Drug Resistance of Brentuximab Vedotin and Its Cytotoxic Payload Monomethyl Auristatin E in Tumor Cells

por Liu-Kreyche, Peggy, Shen, Hong, Marino, Anthony M., Iyer, Ramaswamy A., Humphreys, W. Griffith, Lai, Yurong
Publicado 2019

Comparative untargeted proteomic analysis of ADME proteins and tumor antigens for tumor cell lines

por Gu, Xiaomei, Xiao, Qing, Ruan, Qian, Shu, Yuezhong, Dongre, Ashok, Iyer, Ramaswamy, Humphreys, W. Griffith, Lai, Yurong
Publicado 2018

Tissue distribution and tumor uptake of folate receptor–targeted epothilone folate conjugate, BMS-753493, in CD2F1 mice after systemic administration

por Shen, Hong, Wang, Lifei, Chen, Weiqi, Menard, Krista, Hong, Yang, Tian, Yuan, Bonacorsi, Samuel J., Humphreys, W. Griffith, Lee, Francis Y., Gan, Jinping
Publicado 2016

Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug–Drug Interaction and Associated Biomarker Levels in Healthy Volunteers

por Yee, Sook Wah, Giacomini, Marilyn M., Shen, Hong, Humphreys, W. Griffith, Horng, Howard, Brian, William, Lai, Yurong, Kroetz, Deanna L., Giacomini, Kathleen M.
Publicado 2019