Electroretinographic assessment of rod- and cone-mediated bipolar cell pathways using flicker stimuli in mice

por Tanimoto, Naoyuki, Sothilingam, Vithiyanjali, Kondo, Mineo, Biel, Martin, Humphries, Peter, Seeliger, Mathias W.
Publicado 2015

In Vitro Expanded Stem Cells from the Developing Retina Fail to Generate Photoreceptors but Differentiate into Myelinating Oligodendrocytes

por Czekaj, Magdalena, Haas, Jochen, Gebhardt, Marlen, Müller-Reichert, Thomas, Humphries, Peter, Farrar, Jane, Bartsch, Udo, Ader, Marius
Publicado 2012

Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa

por Loscher, Carol J, Hokamp, Karsten, Kenna, Paul F, Ivens, Alasdair C, Humphries, Peter, Palfi, Arpad, Farrar, G Jane
Publicado 2007

A Novel Retinal Ganglion Cell Promoter for Utility in AAV Vectors

por Hanlon, Killian S., Chadderton, Naomi, Palfi, Arpad, Blanco Fernandez, Alfonso, Humphries, Peter, Kenna, Paul F., Millington-Ward, Sophia, Farrar, G. Jane
Publicado 2017

Target 5000: Target Capture Sequencing for Inherited Retinal Degenerations

por Dockery, Adrian, Stephenson, Kirk, Keegan, David, Wynne, Niamh, Silvestri, Giuliana, Humphries, Peter, Kenna, Paul F., Carrigan, Matthew, Farrar, G. Jane
Publicado 2017

Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho(–/–) mouse

por Palfi, Arpad, Chadderton, Naomi, O’Reilly, Mary, Nagel-Wolfrum, Kerstin, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul, Millington-Ward, Sophia, Farrar, Jane
Publicado 2015

Corrigendum to “Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho–/– mouse”

por Palfi, Arpad, Chadderton, Naomi, O’Reilly, Mary, Nagel-Wolfrum, Kerstin, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul, Millington-Ward, Sophia, Farrar, Jane
Publicado 2016

Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells

por Millington-Ward, Sophia, Chadderton, Naomi, Berkeley, Megan, Finnegan, Laura K., Hanlon, Killian S., Carrigan, Matthew, Humphries, Peter, Kenna, Paul F., Palfi, Arpad, Farrar, G. Jane
Publicado 2020

Panel-Based Population Next-Generation Sequencing for Inherited Retinal Degenerations

por Carrigan, Matthew, Duignan, Emma, Malone, Conor P. G., Stephenson, Kirk, Saad, Tahira, McDermott, Ciara, Green, Andrew, Keegan, David, Humphries, Peter, Kenna, Paul F., Farrar, G. Jane
Publicado 2016

Optimized OPA1 Isoforms 1 and 7 Provide Therapeutic Benefit in Models of Mitochondrial Dysfunction

por Maloney, Daniel M., Chadderton, Naomi, Millington-Ward, Sophia, Palfi, Arpad, Shortall, Ciara, O’Byrne, James J., Cassidy, Lorraine, Keegan, David, Humphries, Peter, Kenna, Paul, Farrar, Gwyneth Jane
Publicado 2020

Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa

por Millington-Ward, Sophia, Chadderton, Naomi, O'Reilly, Mary, Palfi, Arpad, Goldmann, Tobias, Kilty, Claire, Humphries, Marian, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Publicado 2011

Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy

por Chadderton, Naomi, Palfi, Arpad, Millington-Ward, Sophia, Gobbo, Oliverio, Overlack, Nora, Carrigan, Matthew, O'Reilly, Mary, Campbell, Matthew, Ehrhardt, Carsten, Wolfrum, Uwe, Humphries, Peter, Kenna, Paul F, Jane Farrar, G
Publicado 2013

Findings from a Genotyping Study of over 1000 People with Inherited Retinal Disorders in Ireland

por Whelan, Laura, Dockery, Adrian, Wynne, Niamh, Zhu, Julia, Stephenson, Kirk, Silvestri, Giuliana, Turner, Jacqueline, O’Byrne, James J., Carrigan, Matthew, Humphries, Peter, Keegan, David, Kenna, Paul F., Farrar, G. Jane
Publicado 2020

Systemic low-molecular weight drug delivery to pre-selected neuronal regions

por Campbell, Matthew, Humphries, Marian M, Kiang, Anna-Sophia, Nguyen, Anh T H, Gobbo, Oliviero L, Tam, Lawrence C S, Suzuki, Mayu, Hanrahan, Finnian, Ozaki, Ema, Farrar, G-Jane, Kenna, Paul F, Humphries, Peter
Publicado 2011

Optimisation of AAV-NDI1 Significantly Enhances Its Therapeutic Value for Correcting Retinal Mitochondrial Dysfunction

por Chadderton, Naomi, Palfi, Arpad, Maloney, Daniel M., Carrigan, Matthew, Finnegan, Laura K., Hanlon, Killian S., Shortall, Ciara, O’Reilly, Mary, Humphries, Peter, Cassidy, Lorraine, Kenna, Paul F., Millington-Ward, Sophia, Farrar, G. Jane
Publicado 2023

Matrix metalloproteinase-3 (MMP-3)–mediated gene therapy for glaucoma

por O’Callaghan, Jeffrey, Delaney, Conor, O’Connor, Merissa, van Batenburg-Sherwood, Joseph, Schicht, Martin, Lütjen-Drecoll, Elke, Hudson, Natalie, Ni Dhubhghaill, Sorcha, Humphries, Peter, Stanley, Chris, Keravala, Annahita, Chalberg, Thomas, Lawrence, Matthew S., Campbell, Matthew
Publicado 2023

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

por Keaney, James, Walsh, Dominic M., O’Malley, Tiernan, Hudson, Natalie, Crosbie, Darragh E., Loftus, Teresa, Sheehan, Florike, McDaid, Jacqueline, Humphries, Marian M., Callanan, John J., Brett, Francesca M., Farrell, Michael A., Humphries, Peter, Campbell, Matthew
Publicado 2015

Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma

por O’Callaghan, Jeffrey, Crosbie, Darragh. E., Cassidy, Paul. S., Sherwood, Joseph M., Flügel-Koch, Cassandra, Lütjen-Drecoll, Elke, Humphries, Marian M., Reina-Torres, Ester, Wallace, Deborah, Kiang, Anna-Sophia, Campbell, Matthew, Stamer, W. Daniel, Overby, Darryl R., O’Brien, Colm, Tam, Lawrence C. S., Humphries, Peter
Publicado 2017

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

por McDowell, Colleen M., Kizhatil, Krishnakumar, Elliott, Michael H., Overby, Darryl R., van Batenburg-Sherwood, Joseph, Millar, J. Cameron, Kuehn, Markus H., Zode, Gulab, Acott, Ted S., Anderson, Michael G., Bhattacharya, Sanjoy K., Bertrand, Jacques A., Borras, Terete, Bovenkamp, Diane E., Cheng, Lin, Danias, John, De Ieso, Michael Lucio, Du, Yiqin, Faralli, Jennifer A., Fuchshofer, Rudolf, Ganapathy, Preethi S., Gong, Haiyan, Herberg, Samuel, Hernandez, Humberto, Humphries, Peter, John, Simon W. M., Kaufman, Paul L., Keller, Kate E., Kelley, Mary J., Kelly, Ruth A., Krizaj, David, Kumar, Ajay, Leonard, Brian C., Lieberman, Raquel L., Liton, Paloma, Liu, Yutao, Liu, Katy C., Lopez, Navita N., Mao, Weiming, Mavlyutov, Timur, McDonnell, Fiona, McLellan, Gillian J., Mzyk, Philip, Nartey, Andrews, Pasquale, Louis R., Patel, Gaurang C., Pattabiraman, Padmanabhan P., Peters, Donna M., Raghunathan, Vijaykrishna, Rao, Ponugoti Vasantha, Rayana, Naga, Raychaudhuri, Urmimala, Reina-Torres, Ester, Ren, Ruiyi, Rhee, Douglas, Chowdhury, Uttio Roy, Samples, John R., Samples, E. Griffen, Sharif, Najam, Schuman, Joel S., Sheffield, Val C., Stevenson, Cooper H., Soundararajan, Avinash, Subramanian, Preeti, Sugali, Chenna Kesavulu, Sun, Yang, Toris, Carol B., Torrejon, Karen Y., Vahabikashi, Amir, Vranka, Janice A., Wang, Ting, Willoughby, Colin E., Xin, Chen, Yun, Hongmin, Zhang, Hao F., Fautsch, Michael P., Tamm, Ernst R., Clark, Abbot F., Ethier, C. Ross, Stamer, W. Daniel
Publicado 2022