Taking up the reins of power: metabolic functions of p53

por Humpton, Timothy, Vousden, Karen H
Publicado 2019

p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant

por Humpton, Timothy J., Hock, Andreas K., Maddocks, Oliver D. K., Vousden, Karen H.
Publicado 2018

p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl(4)

por Humpton, Timothy J., Hall, Holly, Kiourtis, Christos, Nixon, Colin, Clark, William, Hedley, Ann, Shaw, Robin, Bird, Thomas G., Blyth, Karen, Vousden, Karen H.
Publicado 2021

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

por Tajan, Mylène, Hock, Andreas K., Blagih, Julianna, Robertson, Neil A., Labuschagne, Christiaan F., Kruiswijk, Flore, Humpton, Timothy J., Adams, Peter D., Vousden, Karen H.
Publicado 2018

Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice

por Humpton, Timothy J., Nomura, Koji, Weber, Julia, Magnussen, Helge M., Hock, Andreas K., Nixon, Colin, Dhayade, Sandeep, Stevenson, David, Huang, Danny T., Strathdee, Douglas, Blyth, Karen, Vousden, Karen H.
Publicado 2021

A non-invasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo(†)

por Humpton, Timothy J, Hock, Andreas K, Kiourtis, Christos, Donatis, Marco De, Fercoq, Frederic, Nixon, Colin, Bryson, Sheila, Strathdee, Douglas, Carlin, Leo M., Bird, Thomas G., Blyth, Karen, Vousden, Karen H
Publicado 2022

Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo

por Hock, Andreas K., Cheung, Eric C., Humpton, Timothy J., Monteverde, Tiziana, Paulus-Hock, Viola, Lee, Pearl, McGhee, Ewan, Scopelliti, Alessandro, Murphy, Daniel J., Strathdee, Douglas, Blyth, Karen, Vousden, Karen H.
Publicado 2017

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

por DeNicola, Gina M., Karreth, Florian A., Humpton, Timothy J., Gopinathan, Aarthi, Wei, Cong, Frese, Kristopher, Mangal, Dipti, Yu, Kenneth H., Yeo, Charles J., Calhoun, Eric S., Scrimieri, Francesca, Winter, Jordan M., Hruban, Ralph H., Iacobuzio-Donahue, Christine, Kern, Scott E., Blair, Ian A., Tuveson, David A.
Publicado 2011