Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein

por Leitao, Andre, Bhumkar, Akshay, Hunter, Dominic J. B., Gambin, Yann, Sierecki, Emma
Publicado 2018

A Split-Luciferase Reporter Recognizing GFP and mCherry Tags to Facilitate Studies of Protein–Protein Interactions

por Moustaqil, Mehdi, Bhumkar, Akshay, Gonzalez, Laura, Raoul, Lisa, Hunter, Dominic J. B., Carrive, Pascal, Sierecki, Emma, Gambin, Yann
Publicado 2017

Single-molecule detection on a portable 3D-printed microscope

por Brown, James W. P., Bauer, Arnaud, Polinkovsky, Mark E, Bhumkar, Akshay, Hunter, Dominic J. B., Gaus, Katharina, Sierecki, Emma, Gambin, Yann
Publicado 2019

Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein

por Leitão, André D. G., Rudolffi-Soto, Paulina, Chappard, Alexandre, Bhumkar, Akshay, Lau, Derrick, Hunter, Dominic J. B., Gambin, Yann, Sierecki, Emma
Publicado 2021

Cell-free formation and interactome analysis of caveolae

por Jung, WooRam, Sierecki, Emma, Bastiani, Michele, O’Carroll, Ailis, Alexandrov, Kirill, Rae, James, Johnston, Wayne, Hunter, Dominic J.B., Ferguson, Charles, Gambin, Yann, Ariotti, Nicholas, Parton, Robert G.
Publicado 2018

Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor

por Moustaqil, Mehdi, Fontaine, Frank, Overman, Jeroen, McCann, Alex, Bailey, Timothy L, Rudolffi Soto, Paulina, Bhumkar, Akshay, Giles, Nichole, Hunter, Dominic J B, Gambin, Yann, Francois, Mathias, Sierecki, Emma
Publicado 2018

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88

por O’Carroll, Ailís, Chauvin, Brieuc, Brown, James W. P., Meagher, Ava, Coyle, Joanne, Schill, Jurgen, Bhumkhar, Akshay, Hunter, Dominic J. B., Ve, Thomas, Kobe, Bostjan, Sierecki, Emma, Gambin, Yann
Publicado 2018

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species

por Moustaqil, Mehdi, Ollivier, Emma, Chiu, Hsin-Ping, Van Tol, Sarah, Rudolffi-Soto, Paulina, Stevens, Christian, Bhumkar, Akshay, Hunter, Dominic J. B., Freiberg, Alexander N., Jacques, David, Lee, Benhur, Sierecki, Emma, Gambin, Yann
Publicado 2021

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

por Clabbers, Max T. B., Holmes, Susannah, Muusse, Timothy W., Vajjhala, Parimala R., Thygesen, Sara J., Malde, Alpeshkumar K., Hunter, Dominic J. B., Croll, Tristan I., Flueckiger, Leonie, Nanson, Jeffrey D., Rahaman, Md. Habibur, Aquila, Andrew, Hunter, Mark S., Liang, Mengning, Yoon, Chun Hong, Zhao, Jingjing, Zatsepin, Nadia A., Abbey, Brian, Sierecki, Emma, Gambin, Yann, Stacey, Katryn J., Darmanin, Connie, Kobe, Bostjan, Xu, Hongyi, Ve, Thomas
Publicado 2021