JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis

por Huntwork-Rodriguez, Sarah, Wang, Bei, Watkins, Trent, Ghosh, Arundhati Sengupta, Pozniak, Christine D., Bustos, Daisy, Newton, Kim, Kirkpatrick, Donald S., Lewcock, Joseph W.
Publicado 2013

A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls

por Vissers, Maurits F. J. M., Troyer, Matthew D., Thijssen, Eva, Pereira, Diana R., Heuberger, | Jules A. A. C., Groeneveld, Geert Jan, Huntwork‐Rodriguez, Sarah
Publicado 2023

The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease

por Rideout, Hardy J., Chartier-Harlin, Marie-Christine, Fell, Matthew J., Hirst, Warren D., Huntwork-Rodriguez, Sarah, Leyns, Cheryl E. G., Mabrouk, Omar S., Taymans, Jean-Marc
Publicado 2020

Association of caffeine and related analytes with resistance to Parkinson disease among LRRK2 mutation carriers: A metabolomic study

por Crotty, Grace F., Maciuca, Romeo, Macklin, Eric A., Wang, Junhua, Montalban, Manuel, Davis, Sonnet S., Alkabsh, Jamal I., Bakshi, Rachit, Chen, Xiqun, Ascherio, Alberto, Astarita, Giuseppe, Huntwork-Rodriguez, Sarah, Schwarzschild, Michael A.
Publicado 2020

Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10

por Wang, Xiang, Negrou, Elvira, Maloney, Michael T., Bondar, Vitaliy V., Andrews, Shan V., Montalban, Manuel, Llapashtica, Ceyda, Maciuca, Romeo, Nguyen, Hoang, Solanoy, Hilda, Arguello, Annie, Przybyla, Laralynne, Moerke, Nathan J., Huntwork-Rodriguez, Sarah, Henry, Anastasia G.
Publicado 2021

Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult

por Larhammar, Martin, Huntwork-Rodriguez, Sarah, Jiang, Zhiyu, Solanoy, Hilda, Sengupta Ghosh, Arundhati, Wang, Bei, Kaminker, Joshua S, Huang, Kevin, Eastham-Anderson, Jeffrey, Siu, Michael, Modrusan, Zora, Farley, Madeline M, Tessier-Lavigne, Marc, Lewcock, Joseph W, Watkins, Trent A
Publicado 2017