How homologous recombination generates a mutable genome

por Hurles, Matthew
Publicado 2005

Gene Duplication: The Genomic Trade in Spare Parts

por Hurles, Matthew
Publicado 2004

Gene conversion homogenizes the CMT1A paralogous repeats

por Hurles, Matthew E
Publicado 2001

Shotgun haplotyping: a novel method for surveying allelic sequence variation

por Lindsay, Sarah J., Bonfield, James K., Hurles, Matthew E.
Publicado 2005

Long-range, high-throughput haplotype determination via haplotype-fusion PCR and ligation haplotyping

por Turner, Daniel J., Tyler-Smith, Chris, Hurles, Matthew E.
Publicado 2008

Characterising and Predicting Haploinsufficiency in the Human Genome

por Huang, Ni, Lee, Insuk, Marcotte, Edward M., Hurles, Matthew E.
Publicado 2010

Origins of chromosomal rearrangement hotspots in the human genome: evidence from the AZFa deletion hotspots

por Hurles, Matthew E, Willey, David, Matthews, Lucy, Hussain, Syed Sufyan
Publicado 2004

Empirical research on the ethics of genomic research

por Middleton, Anna, Parker, Michael, Wright, Caroline F, Bragin, Eugene, Hurles, Matthew E
Publicado 2013

The genome-wide effects of ionizing radiation on mutation induction in the mammalian germline

por Adewoye, Adeolu B., Lindsay, Sarah J., Dubrova, Yuri E., Hurles, Matthew E.
Publicado 2015

Recent advances in congenital heart disease genomics

por Wilsdon, Anna, Sifrim, Alejandro, Hitz, Marc-Phillip, Hurles, Matthew, Brook, J. David
Publicado 2017

Similarities and differences in patterns of germline mutation between mice and humans

por Lindsay, Sarah J., Rahbari, Raheleh, Kaplanis, Joanna, Keane, Thomas, Hurles, Matthew E.
Publicado 2019

Quantifying single nucleotide variant detection sensitivity in exome sequencing

por Meynert, Alison M, Bicknell, Louise S, Hurles, Matthew E, Jackson, Andrew P, Taylor, Martin S
Publicado 2013

VarMap: a web tool for mapping genomic coordinates to protein sequence and structure and retrieving protein structural annotations

por Stephenson, James D, Laskowski, Roman A, Nightingale, Andrew, Hurles, Matthew E, Thornton, Janet M
Publicado 2019

Exome Sequencing in Fetuses with Structural Malformations

por Mackie, Fiona L., Carss, Keren J., Hillman, Sarah C., Hurles, Matthew E., Kilby, Mark D.
Publicado 2014

High throughput exome coverage of clinically relevant cardiac genes

por Manase, Dorin, D’Alessandro, Lisa CA, Manickaraj, Ashok Kumar, Al Turki, Saeed, Hurles, Matthew E, Mital, Seema
Publicado 2014

Potential research participants support the return of raw sequence data

por Middleton, Anna, Wright, Caroline F, Morley, Katherine I, Bragin, Eugene, Firth, Helen V, Hurles, Matthew E, Parker, Michael
Publicado 2015

Attitudes of nearly 7000 health professionals, genomic researchers and publics toward the return of incidental results from sequencing research

por Middleton, Anna, Morley, Katherine I, Bragin, Eugene, Firth, Helen V, Hurles, Matthew E, Wright, Caroline F, Parker, Michael
Publicado 2016

Evaluating variants classified as pathogenic in ClinVar in the DDD Study

por Wright, Caroline F., Eberhardt, Ruth Y., Constantinou, Panayiotis, Hurles, Matthew E., FitzPatrick, David R., Firth, Helen V.
Publicado 2020

IMPROVE-DD: Integrating multiple phenotype resources optimizes variant evaluation in genetically determined developmental disorders

por Aitken, Stuart, Firth, Helen V., Wright, Caroline F., Hurles, Matthew E., FitzPatrick, David R., Semple, Colin A.
Publicado 2022

Validity of the Family-Based Association Test for Copy Number Variant Data in the Case of Non-Linear Intensity-Genotype Relationship

por Zanda, Manuela, Onengut, Suna, Walker, Neil, Todd, John A, Clayton, David G, Rich, Stephen S, Hurles, Matthew E, Plagnol, Vincent
Publicado 2012