Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene

por Guo, Kexiao, Gokhale, Vijay, Hurley, Laurence H., Sun, Daekyu
Publicado 2008

I-Motif Structures Formed in the Human c-MYC Promoter Are Highly Dynamic–Insights into Sequence Redundancy and I-Motif Stability

por Dai, Jixun, Hatzakis, Emmanuel, Hurley, Laurence H., Yang, Danzhou
Publicado 2010

Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadrup...

por Sun, Daekyu, Guo, Kexiao, Rusche, Jadrian J., Hurley, Laurence H.
Publicado 2005

3-[4-(10H-Indolo[3,2-b]quinolin-11-yl)piperazin-1-yl]propan-1-ol

por Nichol, Gary S., Boddupally, Peda V. L., De, Biswanath, Hurley, Laurence H.
Publicado 2011

The Transcriptional Complex Between the BCL2 i-Motif and hnRNP LL Is a Molecular Switch for Control of Gene Expression That Can Be Modulated by Small Molecules

por Kang, Hyun-Jin, Kendrick, Samantha, Hecht, Sidney M., Hurley, Laurence H.
Publicado 2014

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region

por Dai, Jixun, Chen, Ding, Jones, Roger A., Hurley, Laurence H., Yang, Danzhou
Publicado 2006

Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4

por Qin, Yong, Rezler, Evonne M., Gokhale, Vijay, Sun, Daekyu, Hurley, Laurence H.
Publicado 2007

Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL

por Cui, Yunxi, Koirala, Deepak, Kang, HyunJin, Dhakal, Soma, Yangyuoru, Philip, Hurley, Laurence H., Mao, Hanbin
Publicado 2014

Identification of G-quadruplexes in long functional RNAs using 7-deaza-Guanine RNA

por Weldon, Carika, Behm-Ansmant, Isabelle, Hurley, Laurence H., Burley, Glenn A., Branlant, Christiane, Eperon, Ian C., Dominguez, Cyril
Publicado 2016

Quindoline-derivatives display potent G-quadruplex-mediated antiviral activity against herpes simplex virus 1

por Frasson, Ilaria, Soldà, Paola, Nadai, Matteo, Tassinari, Martina, Scalabrin, Matteo, Gokhale, Vijay, Hurley, Laurence H., Richter, Sara N.
Publicado 2022

A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity

por Palumbo, SunMi L., Memmott, Regan M., Uribe, Diana J., Krotova-Khan, Yulia, Hurley, Laurence H., Ebbinghaus, Scot W.
Publicado 2008

The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structur...

por Kendrick, Samantha, Kang, Hyun-Jin, Alam, Mohammad P., Madathil, Manikandadas M., Agrawal, Prashansa, Gokhale, Vijay, Yang, Danzhou, Hecht, Sidney M., Hurley, Laurence H.
Publicado 2014

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

por Miranti, Cindy K., Moore, Sara, Kim, Yongeun, Chappeta, Venkateshwar Reddy, Wu, Kui, De, Biswanath, Gokhale, Vijay, Hurley, Laurence H., Reyes-Reyes, Elsa M.
Publicado 2020

Correction: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

por Miranti, Cindy K., Moore, Sara, Kim, Yongeun, Chappeta, Venkateshwar Reddy, Wu, Kui, De, Biswanath, Gokhale, Vijay, Hurley, Laurence H., Reyes-Reyes, Elsa M.
Publicado 2020

Correction to “The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA H...

por Kendrick, Samantha, Kang, Hyun-Jin, Alam, Mohammad P., Madathil, Manikandadas M., Agrawal, Prashansa, Gokhale, Vijay, Yang, Danzhou, Hecht, Sidney M., Hurley, Laurence H.
Publicado 2016

Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X

por Weldon, Carika, Dacanay, Justine G, Gokhale, Vijay, Boddupally, Peda Venkat L, Behm-Ansmant, Isabelle, Burley, Glenn A, Branlant, Christiane, Hurley, Laurence H, Dominguez, Cyril, Eperon, Ian C
Publicado 2018

In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells

por Montoya, Justin J., Turnidge, Megan A., Wai, Daniel H., Patel, Apurvi R., Lee, David W., Gokhale, Vijay, Hurley, Laurence H., Arceci, Robert J., Wetmore, Cynthia, Azorsa, David O.
Publicado 2019

The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer

por Hahn, Tobias, Bradley-Dunlop, Deborah J, Hurley, Laurence H, Von-Hoff, Daniel, Gately, Stephen, Mary, Disis L, Lu, Hailing, Penichet, Manuel L, Besselsen, David G, Cole, Brook B, Meeuwsen, Tanisha, Walker, Edwin, Akporiaye, Emmanuel T
Publicado 2011

Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma

por Liang, Winnie S., Hendricks, William, Kiefer, Jeffrey, Schmidt, Jessica, Sekar, Shobana, Carpten, John, Craig, David W., Adkins, Jonathan, Cuyugan, Lori, Manojlovic, Zarko, Halperin, Rebecca F., Helland, Adrienne, Nasser, Sara, Legendre, Christophe, Hurley, Laurence H., Sivaprakasam, Karthigayini, Johnson, Douglas B., Crandall, Holly, Busam, Klaus J., Zismann, Victoria, Deluca, Valerie, Lee, Jeeyun, Sekulic, Aleksandar, Ariyan, Charlotte E., Sosman, Jeffrey, Trent, Jeffrey
Publicado 2017