Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQ(Q209P)-driven uveal melanomas in zebrafish

por Mouti, Mai Abdel, Dee, Christopher, Coupland, Sarah E., Hurlstone, Adam F.L.
Publicado 2016

Glucose uptake as an alternative to oxygen uptake for assessing metabolic rate in Danio rerio larvae

por Evans, Bridget L., Hurlstone, Adam F.L., Clayton, Peter E., Stevens, Adam, Shiels, Holly A.
Publicado 2022

The Transcription Factor AP-1 Is Required for EGF-induced Activation of Rho-like GTPases, Cytoskeletal Rearrangements, Motility, and In Vitro Invasion of A431 Cells

por Malliri, Angeliki, Symons, Marc, Hennigan, Robert F., Hurlstone, Adam F.L., Lamb, Richard F., Wheeler, Tricia, Ozanne, Bradford W.
Publicado 1998

Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics

por del Ama, Laura Fernandez, Jones, Mary, Walker, Paul, Chapman, Anna, Braun, Julia A., Mohr, Jasmine, Hurlstone, Adam F. L.
Publicado 2016

Impaired neural development in a zebrafish model for Lowe syndrome

por Ramirez, Irene Barinaga-Rementeria, Pietka, Grzegorz, Jones, David R., Divecha, Nullin, Alia, A., Baraban, Scott C., Hurlstone, Adam F. L., Lowe, Martin
Publicado 2012

HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion

por Vaughan, Lynsey, Tan, Chong-Teik, Chapman, Anna, Nonaka, Daisuke, Mack, Natalie A., Smith, Duncan, Booton, Richard, Hurlstone, Adam F.L., Malliri, Angeliki
Publicado 2014

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes

por Dee, Christopher T., Nagaraju, Raghavendar T., Athanasiadis, Emmanouil I., Gray, Caroline, Fernandez del Ama, Laura, Johnston, Simon A., Secombes, Christopher J., Cvejic, Ana, Hurlstone, Adam F. L.
Publicado 2016

Zebrafish IL-4–like Cytokines and IL-10 Suppress Inflammation but Only IL-10 Is Essential for Gill Homeostasis

por Bottiglione, Federica, Dee, Christopher T., Lea, Robert, Zeef, Leo A. H., Badrock, Andrew P., Wane, Madina, Bugeon, Laurence, Dallman, Margaret J., Allen, Judith E., Hurlstone, Adam F. L.
Publicado 2020

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

por Diamantopoulou, Zoi, White, Gavin, Fadlullah, Muhammad Z.H., Dreger, Marcel, Pickering, Karen, Maltas, Joe, Ashton, Garry, MacLeod, Ruth, Baillie, George S., Kouskoff, Valerie, Lacaud, Georges, Murray, Graeme I., Sansom, Owen J., Hurlstone, Adam F.L., Malliri, Angeliki
Publicado 2017

Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached

por Wilcock, Daniel J., Badrock, Andrew P., Wong, Chun W., Owen, Rhys, Guerin, Melissa, Southam, Andrew D., Johnston, Hannah, Telfer, Brian A., Fullwood, Paul, Watson, Joanne, Ferguson, Harriet, Ferguson, Jennifer, Lloyd, Gavin R., Jankevics, Andris, Dunn, Warwick B., Wellbrock, Claudia, Lorigan, Paul, Ceol, Craig, Francavilla, Chiara, Smith, Michael P., Hurlstone, Adam F.L.
Publicado 2022

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models

por Wong, Chun Wai, Evangelou, Christos, Sefton, Kieran N., Leshem, Rotem, Zhang, Wei, Gopalan, Vishaka, Chattrakarn, Sorayut, Fernandez Carro, Macarena Lucia, Uzuner, Erez, Mole, Holly, Wilcock, Daniel J., Smith, Michael P., Sergiou, Kleita, Telfer, Brian A., Isaac, Dervla T., Liu, Chang, Perl, Nicholas R., Marie, Kerrie, Lorigan, Paul, Williams, Kaye J., Rao, Patricia E., Nagaraju, Raghavendar T., Niepel, Mario, Hurlstone, Adam F. L.
Publicado 2023