Oncogenic FGFR3 gene fusions in bladder cancer

por Williams, Sarah V., Hurst, Carolyn D., Knowles, Margaret A.
Publicado 2013

ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer

por di Martino, Erica, Alder, Olivia, Hurst, Carolyn D., Knowles, Margaret A.
Publicado 2019

Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer

por Knowles, Margaret A., Platt, Fiona M., Ross, Rebecca L., Hurst, Carolyn D.
Publicado 2009

A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene

por Hurst, Carolyn D, Zuiverloon, Tahlita CM, Hafner, Christian, Zwarthoff, Ellen C, Knowles, Margaret A
Publicado 2009

Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes

por Taylor, Claire F., Platt, Fiona M., Hurst, Carolyn D., Thygesen, Helene H., Knowles, Margaret A.
Publicado 2014

The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets

por Burns, Julie E., Hurst, Carolyn D., Knowles, Margaret A., Phillips, Roger M., Allison, Simon J.
Publicado 2021

Towards a Next-Generation Sequencing Diagnostic Service for Tumour Genotyping: A Comparison of Panels and Platforms

por Burghel, George J., Hurst, Carolyn D., Watson, Christopher M., Chambers, Phillip A., Dickinson, Helen, Roberts, Paul, Knowles, Margaret A.
Publicado 2015

Two Multiplex Assays That Simultaneously Identify 22 Possible Mutation Sites in the KRAS, BRAF, NRAS and PIK3CA Genes

por Lurkin, Irene, Stoehr, Robert, Hurst, Carolyn D., van Tilborg, Angela A. G., Knowles, Margaret A., Hartmann, Arndt, Zwarthoff, Ellen C.
Publicado 2010

Polycomb Repressor Complex 1 Member, BMI1 Contributes to Urothelial Tumorigenesis through p16-Independent Mechanisms()

por De Faveri, Lia E., Hurst, Carolyn D., Roulson, Jo-An, Wood, Henry, Sanchez-Carbayo, Marta, Knowles, Margaret A., Chapman, Emma J.
Publicado 2015

Molecular profile of pure squamous cell carcinoma of the bladder identifies major roles for OSMR and YAP signalling

por Hurst, Carolyn D, Cheng, Guo, Platt, Fiona M, Alder, Olivia, Black, Emma VI, Burns, Julie E, Brown, Joanne, Jain, Sunjay, Roulson, Jo‐An, Knowles, Margaret A
Publicado 2022

Development of resistance to FGFR inhibition in urothelial carcinoma via multiple pathways in vitro

por Pettitt, Geoffrey A, Hurst, Carolyn D, Khan, Zubeda, McPherson, Helen R, Dunning, Matthew C, Alder, Olivia, Platt, Fiona M, Black, Emma VI, Burns, Julie E, Knowles, Margaret A
Publicado 2022

A transcriptional network of cell cycle dysregulation in noninvasive papillary urothelial carcinoma

por Warrick, Joshua I., Knowles, Margaret A., Hurst, Carolyn D., Shuman, Lauren, Raman, Jay D., Walter, Vonn, Putt, Jeffrey, Dyrskjøt, Lars, Groeneveld, Clarice, Castro, Mauro A. A., Robertson, A. Gordon, DeGraff, David J.
Publicado 2022

Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight

por Hurst, Carolyn D., Cheng, Guo, Platt, Fiona M., Castro, Mauro A.A., Marzouka, Nour-al-dain S., Eriksson, Pontus, Black, Emma V.I., Alder, Olivia, Lawson, Andrew R.J., Lindskrog, Sia V., Burns, Julie E., Jain, Sunjay, Roulson, Jo-An, Brown, Joanne C., Koster, Jan, Robertson, A. Gordon, Martincorena, Inigo, Dyrskjøt, Lars, Höglund, Mattias, Knowles, Margaret A.
Publicado 2021

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

por Lindskrog, Sia Viborg, Prip, Frederik, Lamy, Philippe, Taber, Ann, Groeneveld, Clarice S., Birkenkamp-Demtröder, Karin, Jensen, Jørgen Bjerggaard, Strandgaard, Trine, Nordentoft, Iver, Christensen, Emil, Sokac, Mateo, Birkbak, Nicolai J., Maretty, Lasse, Hermann, Gregers G., Petersen, Astrid C., Weyerer, Veronika, Grimm, Marc-Oliver, Horstmann, Marcus, Sjödahl, Gottfrid, Höglund, Mattias, Steiniche, Torben, Mogensen, Karin, de Reyniès, Aurélien, Nawroth, Roman, Jordan, Brian, Lin, Xiaoqi, Dragicevic, Dejan, Ward, Douglas G., Goel, Anshita, Hurst, Carolyn D., Raman, Jay D., Warrick, Joshua I., Segersten, Ulrika, Sikic, Danijel, van Kessel, Kim E. M., Maurer, Tobias, Meeks, Joshua J., DeGraff, David J., Bryan, Richard T., Knowles, Margaret A., Simic, Tatjana, Hartmann, Arndt, Zwarthoff, Ellen C., Malmström, Per-Uno, Malats, Núria, Real, Francisco X., Dyrskjøt, Lars
Publicado 2021