A perspective on structural and mechanistic aspects of protein O-fucosylation

por Lira-Navarrete, Erandi, Hurtado-Guerrero, Ramon
Publicado 2018

Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase

por Raimi, Olawale G., Hurtado-Guerrero, Ramon, vanAalten, Daan M.F.
Publicado 2018

Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation

por Sanz-Martinez, Ignacio, Pereira, Sandra, Merino, Pedro, Corzana, Francisco, Hurtado-Guerrero, Ramon
Publicado 2023

The Essential Role of Water Molecules in the Reaction Mechanism of Protein O‐Fucosyltransferase 2

por Sanz‐Martínez, Ignacio, García‐García, Ana, Tejero, Tomás, Hurtado‐Guerrero, Ramón, Merino, Pedro
Publicado 2022

Kinetic and functional properties of human mitochondrial phosphoenolpyruvate carboxykinase

por Escós, Miriam, Latorre, Pedro, Hidalgo, Jorge, Hurtado-Guerrero, Ramón, Carrodeguas, José Alberto, López-Buesa, Pascual
Publicado 2016

Asparagine Tautomerization in Glycosyltransferase Catalysis. The Molecular Mechanism of Protein O-Fucosyltransferase 1

por Piniello, Beatriz, Lira-Navarrete, Erandi, Takeuchi, Hideyuki, Takeuchi, Megumi, Haltiwanger, Robert S., Hurtado-Guerrero, Ramón, Rovira, Carme
Publicado 2021

Crystal Structure of the FAD-Containing Ferredoxin-NADP(+) Reductase from the Plant Pathogen Xanthomonas axonopodis pv. citri

por Tondo, María Laura, Hurtado-Guerrero, Ramon, Ceccarelli, Eduardo A., Medina, Milagros, Orellano, Elena G., Martínez-Júlvez, Marta
Publicado 2013

Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target

por Rodríguez-Cárdenas, Ángela, Rojas, Adriana L., Conde-Giménez, María, Velázquez-Campoy, Adrián, Hurtado-Guerrero, Ramón, Sancho, Javier
Publicado 2016

Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase

por García-García, Ana, Ceballos-Laita, Laura, Serna, Sonia, Artschwager, Raik, Reichardt, Niels C., Corzana, Francisco, Hurtado-Guerrero, Ramon
Publicado 2020

NleB/SseK-catalyzed arginine-glycosylation and enteropathogen virulence are finely tuned by a single variable position contiguous to the catalytic machinery

por García-García, Ana, Hicks, Thomas, El Qaidi, Samir, Zhu, Congrui, Hardwidge, Philip R., Angulo, Jesús, Hurtado-Guerrero, Ramon
Publicado 2021

Production of a Granulysin-Based, Tn-Targeted Cytolytic Immunotoxin Using Pulsed Electric Field Technology

por Guerrero-Ochoa, Patricia, Aguilar-Machado, Diederich, Ibáñez-Pérez, Raquel, Macías-León, Javier, Hurtado-Guerrero, Ramón, Raso, Javier, Anel, Alberto
Publicado 2020

Protein O-Fucosyltransferase 1 Undergoes Interdomain Flexibility in Solution

por Lira-Navarrete, Erandi, Pallarés, María Carmen, Castello, Fabio, Ruedas-Rama, Maria J., Orte, Angel, Lostao, Anabel, Hurtado-Guerrero, Ramón
Publicado 2021

Structural Insights into the Mechanism of Protein O-Fucosylation

por Lira-Navarrete, Erandi, Valero-González, Jessika, Villanueva, Raquel, Martínez-Júlvez, Marta, Tejero, Tomás, Merino, Pedro, Panjikar, Santosh, Hurtado-Guerrero, Ramon
Publicado 2011

The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements

por Sebastián, María, Lira-Navarrete, Erandi, Serrano, Ana, Marcuello, Carlos, Velázquez-Campoy, Adrián, Lostao, Anabel, Hurtado-Guerrero, Ramón, Medina, Milagros, Martínez-Júlvez, Marta
Publicado 2017

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor

por Raimi, Olawale G., Hurtado-Guerrero, Ramon, Borodkin, Vladimir, Ferenbach, Andrew, Urbaniak, Michael D., Ferguson, Michael A. J., van Aalten, Daan M. F.
Publicado 2020

O-fucosylation stabilizes the TSR3 motif in thrombospondin-1 by interacting with nearby amino acids and protecting a disulfide bond

por Berardinelli, Steven J., Eletsky, Alexander, Valero-González, Jessika, Ito, Atsuko, Manjunath, Rajashri, Hurtado-Guerrero, Ramon, Prestegard, James H., Woods, Robert J., Haltiwanger, Robert S.
Publicado 2022

Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

por Serrán-Aguilera, Lucía, Denton, Helen, Rubio-Ruiz, Belén, López-Gutiérrez, Borja, Entrena, Antonio, Izquierdo, Luis, Smith, Terry K., Conejo-García, Ana, Hurtado-Guerrero, Ramon
Publicado 2016

Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases

por Fang, Wenxia, Sanz, Ana Belén, Bartual, Sergio Galan, Wang, Bin, Ferenbach, Andrew T., Farkaš, Vladimír, Hurtado-Guerrero, Ramon, Arroyo, Javier, van Aalten, Daan M. F.
Publicado 2019

Plasmodium falciparum Apicomplexan-Specific Glucosamine-6-Phosphate N-Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development

por Chi, Jordi, Cova, Marta, de las Rivas, Matilde, Medina, Ana, Borges, Rafael Junqueira, Leivar, Pablo, Planas, Antoni, Usón, Isabel, Hurtado-Guerrero, Ramón, Izquierdo, Luis
Publicado 2020

Structural basis for the synthesis of the core 1 structure by C1GalT1

por González-Ramírez, Andrés Manuel, Grosso, Ana Sofia, Yang, Zhang, Compañón, Ismael, Coelho, Helena, Narimatsu, Yoshiki, Clausen, Henrik, Marcelo, Filipa, Corzana, Francisco, Hurtado-Guerrero, Ramon
Publicado 2022