Acetyl-CoA carboxylase inhibitor increases LDL-apoB production rate in NASH with cirrhosis: prevention by fenofibrate

por Dandan, Mohamad, Han, Julia, Mann, Sabrina, Kim, Rachael, Li, Kelvin, Mohammed, Hussein, Chuang, Jen-Chieh, Zhu, Kaiyi, Billin, Andrew N., Huss, Ryan S., Chung, Chuhan, Myers, Robert P., Hellerstein, Marc
Publicado 2023

Elevated de novo lipogenesis, slow liver triglyceride turnover, and clinical correlations in nonalcoholic steatohepatitis patients

por Lawitz, Eric J., Li, Kelvin W., Nyangau, Edna, Field, Tyler John, Chuang, Jen-Chieh, Billin, Andrew, Wang, Lulu, Wang, Ya, Huss, Ryan S., Chung, Chuhan, Subramanian, G. Mani, Myers, Robert P., Hellerstein, Marc K.
Publicado 2022

Integration of deep learning-based histopathology and transcriptomics reveals key genes associated with fibrogenesis in patients with advanced NASH

por Conway, Jake, Pouryahya, Maryam, Gindin, Yevgeniy, Pan, David Z., Carrasco-Zevallos, Oscar M., Mountain, Victoria, Subramanian, G. Mani, Montalto, Michael C., Resnick, Murray, Beck, Andrew H., Huss, Ryan S., Myers, Robert P., Taylor-Weiner, Amaro, Wapinski, Ilan, Chung, Chuhan
Publicado 2023

Improvements of Fibrosis and Disease Activity Are Associated With Improvement of Patient‐Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis

por Younossi, Zobair M., Stepanova, Maria, Noureddin, Mazen, Kowdley, Kris V., Strasser, Simone I., Kohli, Anita, Ruane, Peter, Shiffman, Mitchell L., Sheikh, Aasim, Gunn, Nadege, Caldwell, Stephen H., Huss, Ryan S., Myers, Robert P., Wai‐Sun Wong, Vincent, Alkhouri, Naim, Goodman, Zachary, Loomba, Rohit
Publicado 2021

Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD

por Smirnova, Ekaterina, Muthiah, Mark D., Narayan, Nicole, Siddiqui, Mohamad S., Puri, Puneet, Luketic, Velimir A., Contos, Melissa J., Idowu, Michael, Chuang, Jen‐Chieh, Billin, Andrew N., Huss, Ryan S., Myers, Robert P., Boyett, Sherry, Seneshaw, Mulugeta, Min, Hae‐Ki, Mirshahi, Faridodin, Sanyal, Arun J.
Publicado 2022

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

por Xu, Jun, Wang, Ya, Khoshdeli, Mina, Peach, Matt, Chuang, Jen‐Chieh, Lin, Julie, Tsai, Wen‐Wei, Mahadevan, Sangeetha, Minto, Wesley, Diehl, Lauri, Gupta, Ruchi, Trauner, Michael, Patel, Keyur, Noureddin, Mazen, Kowdley, Kris V., Gulamhusein, Aliya, Bowlus, Christopher L., Huss, Ryan S., Myers, Robert P., Chung, Chuhan, Billin, Andrew N.
Publicado 2023

Enhanced diagnosis of advanced fibrosis and cirrhosis in individuals with NAFLD using FibroScan-based Agile scores

por Sanyal, Arun J., Foucquier, Julie, Younossi, Zobair M., Harrison, Stephen A., Newsome, Philip N., Chan, Wah-Kheong, Yilmaz, Yusuf, De Ledinghen, Victor, Costentin, Charlotte, Zheng, Ming-Hua, Wong, Vincent Wai-Sun, Elkhashab, Magdy, Huss, Ryan S., Myers, Robert P., Roux, Marine, Labourdette, Aymeric, Destro, Marie, Fournier-Poizat, Céline, Miette, Véronique, Sandrin, Laurent, Boursier, Jérôme
Publicado 2023

Cirrhosis regression is associated with improved clinical outcomes in patients with nonalcoholic steatohepatitis

por Sanyal, Arun J., Anstee, Quentin M., Trauner, Michael, Lawitz, Eric J., Abdelmalek, Manal F., Ding, Dora, Han, Ling, Jia, Catherine, Huss, Ryan S., Chung, Chuhan, Wong, Vincent Wai‐Sun, Okanoue, Takeshi, Romero‐Gomez, Manuel, Muir, Andrew J., Afdhal, Nezam H., Bosch, Jaime, Goodman, Zachary, Harrison, Stephen A., Younossi, Zobair M., Myers, Robert P.
Publicado 2022

A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH

por Taylor‐Weiner, Amaro, Pokkalla, Harsha, Han, Ling, Jia, Catherine, Huss, Ryan, Chung, Chuhan, Elliott, Hunter, Glass, Benjamin, Pethia, Kishalve, Carrasco‐Zevallos, Oscar, Shukla, Chinmay, Khettry, Urmila, Najarian, Robert, Taliano, Ross, Subramanian, G. Mani, Myers, Robert P., Wapinski, Ilan, Khosla, Aditya, Resnick, Murray, Montalto, Michael C., Anstee, Quentin M., Wong, Vincent Wai‐Sun, Trauner, Michael, Lawitz, Eric J., Harrison, Stephen A., Okanoue, Takeshi, Romero‐Gomez, Manuel, Goodman, Zachary, Loomba, Rohit, Beck, Andrew H., Younossi, Zobair M.
Publicado 2021