Distinctive transcriptomic and epigenomic signatures of bone marrow-derived myeloid cells and microglia in CNS autoimmunity

por Manouchehri, Navid, Salinas, Victor H., Hussain, Rehana Z., Stüve, Olaf
Publicado 2023

Efficacy of Disease Modifying Therapies in Progressive MS and How Immune Senescence May Explain Their Failure

por Manouchehri, Navid, Salinas, Victor H., Rabi Yeganeh, Negar, Pitt, David, Hussain, Rehana Z., Stuve, Olaf
Publicado 2022

Defining standard enzymatic dissociation methods for individual brains and spinal cords in EAE

por Hussain, Rehana Z., Miller-Little, William A., Doelger, Richard, Cutter, Gary R., Loof, Nicolas, Cravens, Petra D., Stüve, Olaf
Publicado 2018

IL-12/IL-23p40 Is Highly Expressed in Secondary Lymphoid Organs and the CNS during All Stages of EAE, but Its Deletion Does Not Affect Disease Perpetuation

por Cravens, Petra D., Hussain, Rehana Z., Miller-Little, William A., Ben, Li-Hong, Segal, Benjamin M., Herndon, Emily, Stüve, Olaf
Publicado 2016

The sequential natalizumab – alemtuzumab therapy in patients with relapsing forms of multiple sclerosis (SUPPRESS) trial – Part I: Rationale and objectives

por Hussain, Rehana Z, Sguigna, Peter V, Okai, Annette, Wright, Crystal, Madinawala, Mariam, Bass, Ann D, Cutter, Gary R, Manouchehri, Navid, Stuve, Olaf
Publicado 2022

TLR3 agonism re‐establishes CNS immune competence during α4‐integrin deficiency

por Hussain, Rehana Z., Cravens, Petra C., Doelger, Richard, Dentel, Brianne, Herndon, Emily, Loof, Nicolas, Tsai, Peter, Okuda, Darin T., Racke, Michael K., Stüve, Olaf
Publicado 2018

α4-integrin deficiency in B cells does not affect disease in a T-cell–mediated EAE disease model

por Hussain, Rehana Z., Cravens, Petra D., Miller-Little, William A., Doelger, Richard, Granados, Valerie, Herndon, Emily, Okuda, Darin T., Eagar, Todd N., Stüve, Olaf
Publicado 2019

Clinical trials in multiple sclerosis: potential future trial designs

por Manouchehri, Navid, Zhang, Yinan, Salter, Amber, Hussain, Rehana Z., Hartung, Hans-Peter, Hemmer, Bernhard, Linker, Ralf, Segal, Benjamin M., Cutter, Gary, Stüve, Olaf
Publicado 2019

A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR

por Arellano, Benjamine, Hussain, Rehana, Miller-Little, William A., Herndon, Emily, Lambracht-Washington, Doris, Eagar, Todd N., Lewis, Robert, Healey, Don, Vernino, Steven, Greenberg, Benjamin M., Stüve, Olaf
Publicado 2016

Lymph node-derived donor encephalitogenic CD4(+ )T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet

por Cravens, Petra D, Hussain, Rehana Z, Zacharias, Tresa E, Ben, Li-Hong, Herndon, Emily, Vinnakota, Ramya, Lambracht-Washington, Doris, Nessler, Stefan, Zamvil, Scott S, Eagar, Todd N, Stüve, Olaf
Publicado 2011

The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis

por Cravens, Petra D, Kieseier, Bernd C, Hussain, Rehana, Herndon, Emily, Arellano, Benjamine, Ben, Li-Hong, Timmons, Brenda C, Castro-Rojas, Cyd, Hartung, Hans-Peter, Hemmer, Bernhard, Weber, Martin S, Zamvil, Scott S, Stüve, Olaf
Publicado 2013

MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis

por Kuhbandner, Kristina, Hammer, Anna, Haase, Stefanie, Terbrack, Elisa, Hoffmann, Alana, Schippers, Angela, Wagner, Norbert, Hussain, Rehana Z., Miller-Little, William A., Koh, Andrew Y., Stoolman, Joshua S., Segal, Benjamin M., Linker, Ralf A., Stüve, Olaf
Publicado 2019

CD11c(+)CD88(+)CD317(+) myeloid cells are critical mediators of persistent CNS autoimmunity

por Manouchehri, Navid, Hussain, Rehana Z., Cravens, Petra D., Esaulova, Ekaterina, Artyomov, Maxim N., Edelson, Brian T., Wu, Gregory F., Cross, Anne H., Doelger, Richard, Loof, Nicolas, Eagar, Todd N., Forsthuber, Thomas G., Calvier, Laurent, Herz, Joachim, Stüve, Olaf
Publicado 2021

Rituximab Therapy Reduces Organ-Specific T Cell Responses and Ameliorates Experimental Autoimmune Encephalomyelitis

por Monson, Nancy L., Cravens, Petra, Hussain, Rehana, Harp, Christopher T., Cummings, Matthew, de Pilar Martin, Maria, Ben, Li-Hong, Do, Julie, Lyons, Jeri-Anne, Lovette-Racke, Amy, Cross, Anne H., Racke, Michael K., Stüve, Olaf, Shlomchik, Mark, Eagar, Todd N.
Publicado 2011

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

por Ghoreschi, Kamran, Brück, Jürgen, Kellerer, Christina, Deng, Caishu, Peng, Haiyan, Rothfuss, Oliver, Hussain, Rehana Z., Gocke, Anne R., Respa, Annedore, Glocova, Ivana, Valtcheva, Nadejda, Alexander, Eva, Feil, Susanne, Feil, Robert, Schulze-Osthoff, Klaus, Rupec, Rudolf A., Lovett-Racke, Amy E., Dringen, Ralf, Racke, Michael K., Röcken, Martin
Publicado 2011

Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling

por Hu, Wei, Nessler, Stefan, Hemmer, Bernhard, Eagar, Todd N., Kane, Lawrence P., Leliveld, S. Rutger, Müller-Schiffmann, Andreas, Gocke, Anne R., Lovett-Racke, Amy, Ben, Li-Hong, Hussain, Rehana Z., Breil, Andreas, Elliott, Jeffrey L., Puttaparthi, Krishna, Cravens, Petra D., Singh, Mahendra P., Petsch, Benjamin, Stitz, Lothar, Racke, Michael K., Korth, Carsten, Stüve, Olaf
Publicado 2010