Drug Repurposing Approaches towards Defeating Multidrug-Resistant Gram-Negative Pathogens: Novel Polymyxin/Non-Antibiotic Combinations

por Koh Jing Jie, Augustine, Hussein, Maytham, Rao, Gauri G., Li, Jian, Velkov, Tony
Publicado 2022

Bifunctional antibiotic hybrids: A review of clinical candidates

por Koh, Augustine Jing Jie, Thombare, Varsha, Hussein, Maytham, Rao, Gauri G., Li, Jian, Velkov, Tony
Publicado 2023

Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against Acinetobacter baumannii: A Metabolomic Study

por Hussein, Maytham, Allobawi, Rafah, Levou, Irini, Blaskovich, Mark A. T., Rao, Gauri G., Li, Jian, Velkov, Tony
Publicado 2022

The Antimicrobial Activity of Cannabinoids

por Karas, John A., Wong, Labell J. M., Paulin, Olivia K. A., Mazeh, Amna C., Hussein, Maytham H., Li, Jian, Velkov, Tony
Publicado 2020

Untargeted metabolomics to evaluate polymyxin B toxicodynamics following direct intracerebroventricular administration into the rat brain

por Hussein, Maytham, Oberrauch, Sara, Allobawi, Rafah, Cornthwaite-Duncan, Linda, Lu, Jing, Sharma, Rajnikant, Baker, Mark, Li, Jian, Rao, Gauri G., Velkov, Tony
Publicado 2022

Comparative Proteomics of Outer Membrane Vesicles from Polymyxin-Susceptible and Extremely Drug-Resistant Klebsiella pneumoniae

por Hussein, Maytham, Jasim, Raad, Gocol, Hakan, Baker, Mark, Thombare, Varsha J., Ziogas, James, Purohit, Aayush, Rao, Gauri G., Li, Jian, Velkov, Tony
Publicado 2023

Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination

por Veit, Guido, Roldan, Ariel, Hancock, Mark A., Da Fonte, Dillon F., Xu, Haijin, Hussein, Maytham, Frenkiel, Saul, Matouk, Elias, Velkov, Tony, Lukacs, Gergely L.
Publicado 2020

Unique mechanistic insights into pathways associated with the synergistic activity of polymyxin B and caspofungin against multidrug-resistant Klebsiella pneumoniae

por Hussein, Maytham, Wong, Labell J.M., Zhao, Jinxin, Rees, Vanessa E., Allobawi, Rafah, Sharma, Rajnikant, Rao, Gauri G., Baker, Mark, Li, Jian, Velkov, Tony
Publicado 2022

Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens

por Hussein, Maytham, Hu, Xiaohan, Paulin, Olivia K.A., Crawford, Simon, Tony Zhou, Qi, Baker, Mark, Schneider-Futschik, Elena K., Zhu, Yan, Li, Jian, Velkov, Tony
Publicado 2020

Lipidomic Analysis of the Outer Membrane Vesicles from Paired Polymyxin-Susceptible and -Resistant Klebsiella pneumoniae Clinical Isolates

por Jasim, Raad, Han, Mei-Ling, Zhu, Yan, Hu, Xiaohan, Hussein, Maytham H., Lin, Yu-Wei, Zhou, Qi (Tony), Dong, Charlie Yao Da, Li, Jian, Velkov, Tony
Publicado 2018

The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study

por Hussein, Maytham, Karas, John A., Schneider-Futschik, Elena K., Chen, Fan, Swarbrick, James, Paulin, Olivia K. A., Hoyer, Daniel, Baker, Mark, Zhu, Yan, Li, Jian, Velkov, Tony
Publicado 2020

Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR Pseudomonas aerug...

por Hussein, Maytham, Han, Mei-Ling, Zhu, Yan, Schneider-Futschik, Elena K., Hu, Xiaohan, Zhou, Qi Tony, Lin, Yu-Wei, Anderson, Dovile, Creek, Darren J., Hoyer, Daniel, Li, Jian, Velkov, Tony
Publicado 2018