The Extracytoplasmic Domain of the Mycobacterium tuberculosis Ser/Thr Kinase PknB Binds Specific Muropeptides and Is Required for PknB Localization

por Mir, Mushtaq, Asong, Jinkeng, Li, Xiuru, Cardot, Jessica, Boons, Geert-Jan, Husson, Robert N.
Publicado 2011

Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis

por Young, Albert T., Carette, Xavier, Helmel, Michaela, Steen, Hanno, Husson, Robert N., Quackenbush, John, Platig, John
Publicado 2021

Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates

por Chou, Michael F., Prisic, Sladjana, Lubner, Joshua M., Church, George M., Husson, Robert N., Schwartz, Daniel
Publicado 2012

Development of a model of focal pneumococcal pneumonia in young rats

por Malley, Richard, Stack, Anne M, Husson, Robert N, Thompson, Claudette M, Fleisher, Gary R, Saladino, Richard A
Publicado 2004

Accurate target identification for Mycobacterium tuberculosis endoribonuclease toxins requires expression in their native host

por Cintrón, Melvilí, Zeng, Ju-Mei, Barth, Valdir C., Cruz, Jonathan W., Husson, Robert N., Woychik, Nancy A.
Publicado 2019

Toxin-mediated ribosome stalling reprograms the Mycobacterium tuberculosis proteome

por Barth, Valdir C., Zeng, Ju-Mei, Vvedenskaya, Irina O., Ouyang, Ming, Husson, Robert N., Woychik, Nancy A.
Publicado 2019

Investigating essential gene function in Mycobacterium tuberculosis using an efficient CRISPR interference system

por Singh, Atul K., Carette, Xavier, Potluri, Lakshmi-Prasad, Sharp, Jared D., Xu, Ranfei, Prisic, Sladjana, Husson, Robert N.
Publicado 2016

MRSA septic pulmonary emboli presenting as isolated focal chest pain in an adolescent

por Rabinowitz, Danielle G., Chrzanowski, Stephen M., Campbell, Jeffrey I., Davis, Jaclyn, Husson, Robert N., Casey, Alicia M., Marcus, Carolyn H.
Publicado 2020

tRNA is a new target for cleavage by a MazF toxin

por Schifano, Jason M., Cruz, Jonathan W., Vvedenskaya, Irina O., Edifor, Regina, Ouyang, Ming, Husson, Robert N., Nickels, Bryce E., Woychik, Nancy A.
Publicado 2016

BCG as a Case Study for Precision Vaccine Development: Lessons From Vaccine Heterogeneity, Trained Immunity, and Immune Ontogeny

por Angelidou, Asimenia, Diray-Arce, Joann, Conti, Maria Giulia, Smolen, Kinga K., van Haren, Simon Daniël, Dowling, David J., Husson, Robert N., Levy, Ofer
Publicado 2020

A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity

por Ymele-Leki, Patrick, Cao, Shugeng, Sharp, Jared, Lambert, Kathleen G., McAdam, Alexander J., Husson, Robert N., Tamayo, Giselle, Clardy, Jon, Watnick, Paula I.
Publicado 2012

Correction: A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity

por Ymele-Leki, Patrick, Cao, Shugeng, Sharp, Jared, Lambert, Kathleen G., McAdam, Alexander J., Husson, Robert N., Tamayo, Giselle, Clardy, Jon, Watnick, Paula I.
Publicado 2012

Correction: A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity

por Ymele-Leki, Patrick, Cao, Shugeng, Sharp, Jared, Lambert, Kathleen G., McAdam, Alexander J., Husson, Robert N., Tamayo, Giselle, Clardy, Jon, Watnick, Paula I.
Publicado 2012

Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility

por Zeng, Jumei, Platig, John, Cheng, Tan-Yun, Ahmed, Saima, Skaf, Yara, Potluri, Lakshmi-Prasad, Schwartz, Daniel, Steen, Hanno, Moody, D. Branch, Husson, Robert N.
Publicado 2020

Comprehensive Definition of the SigH Regulon of Mycobacterium tuberculosis Reveals Transcriptional Control of Diverse Stress Responses

por Sharp, Jared D., Singh, Atul K., Park, Sang Tae, Lyubetskaya, Anna, Peterson, Matthew W., Gomes, Antonio L. C., Potluri, Lakshmi-Prasad, Raman, Sahadevan, Galagan, James E., Husson, Robert N.
Publicado 2016

Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface

por Carette, Xavier, Platig, John, Young, David C., Helmel, Michaela, Young, Albert T., Wang, Zhe, Potluri, Lakshmi-Prasad, Moody, Cameron Stuver, Zeng, Jumei, Prisic, Sladjana, Paulson, Joseph N., Muntel, Jan, Madduri, Ashoka V. R., Velarde, Jorge, Mayfield, Jacob A., Locher, Christopher, Wang, Tiansheng, Quackenbush, John, Rhee, Kyu Y., Moody, D. Branch, Steen, Hanno, Husson, Robert N.
Publicado 2018