Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

por Lamming, Dudley W, Mihaylova, Maria M, Katajisto, Pekka, Baar, Emma L, Yilmaz, Omer H, Hutchins, Amanda, Gultekin, Yetis, Gaither, Rachel, Sabatini, David M
Publicado 2014

MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

por Birsoy, Kivanc, Wang, Tim, Possemato, Richard, Yilmaz, Omer H., Koch, Catherine E., Chen, Walter W., Hutchins, Amanda W., Gultekin, Yetis, Peterson, Tim R., Carette, Jan E., Brummelkamp, Thijn R., Clish, Clary B., Sabatini, David M.
Publicado 2012

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small cell lung cancer in preclinical models

por Svensson, Robert U., Parker, Seth J., Eichner, Lillian J., Kolar, Matthew J., Wallace, Martina, Brun, Sonja N., Lombardo, Portia S., Van Nostrand, Jeanine L., Hutchins, Amanda, Vera, Lilliana, Gerken, Laurie, Greenwood, Jeremy, Bhat, Sathesh, Harriman, Geraldine, Westlin, William F., Harwood, H. James, Saghatelian, Alan, Kapeller, Rosana, Metallo, Christian M., Shaw, Reuben J.
Publicado 2016