Lack of collagen XV is protective after ischemic stroke in mice

por Dhungana, Hiramani, Huuskonen, Mikko T, Pihlajaniemi, Taina, Heljasvaara, Ritva, Vivien, Denis, Kanninen, Katja M, Malm, Tarja, Koistinaho, Jari, Lemarchant, Sighild
Publicado 2017

Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation

por Dhungana, Hiramani, Huuskonen, Mikko T., Jaronen, Merja, Lemarchant, Sighild, Ali, Humair, Keksa-Goldsteine, Velta, Goldsteins, Gundars, Kanninen, Katja M., Koistinaho, Jari, Malm, Tarja
Publicado 2017

Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation

por Byts, Nadiya, Sharma, Subodh, Malm, Tarja, Kaakinen, Mika, Korhonen, Paula, Jaakkonen, Laura, Keuters, Meike, Huuskonen, Mikko, Pietilä, Ilkka, Koistinaho, Jari, Koivunen, Peppi, Myllyharju, Johanna
Publicado 2022

Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C

por Huuskonen, Mikko T., Wang, Yaoming, Nikolakopoulou, Angeliki Maria, Montagne, Axel, Dai, Zhonghua, Lazic, Divna, Sagare, Abhay P., Zhao, Zhen, Fernandez, Jose A., Griffin, John H., Zlokovic, Berislav V.
Publicado 2021

Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A

por Nikolakopoulou, Angeliki Maria, Wang, Yaoming, Ma, Qingyi, Sagare, Abhay P., Montagne, Axel, Huuskonen, Mikko T., Rege, Sanket V., Kisler, Kassandra, Dai, Zhonghua, Körbelin, Jakob, Herz, Joachim, Zhao, Zhen, Zlokovic, Berislav V.
Publicado 2021

Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion

por Huuskonen, Mikko T., Liu, Qinghai, Lamorie-Foote, Krista, Shkirkova, Kristina, Connor, Michelle, Patel, Arati, Montagne, Axel, Baertsch, Hans, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E., Zlokovic, Berislav V., Mack, William J.
Publicado 2021

Proteomic and functional analyses in disease models reveal CLN5 protein involvement in mitochondrial dysfunction

por Doccini, Stefano, Morani, Federica, Nesti, Claudia, Pezzini, Francesco, Calza, Giulio, Soliymani, Rabah, Signore, Giovanni, Rocchiccioli, Silvia, Kanninen, Katja M., Huuskonen, Mikko T., Baumann, Marc H., Simonati, Alessandro, Lalowski, Maciej M., Santorelli, Filippo M.
Publicado 2020

A “multi-omics” analysis of blood–brain barrier and synaptic dysfunction in APOE4 mice

por Barisano, Giuseppe, Kisler, Kassandra, Wilkinson, Brent, Nikolakopoulou, Angeliki Maria, Sagare, Abhay P., Wang, Yaoming, Gilliam, William, Huuskonen, Mikko T., Hung, Shu-Ting, Ichida, Justin K., Gao, Fan, Coba, Marcelo P., Zlokovic, Berislav V.
Publicado 2022

Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy

por Huuskonen, Mikko T., Loppi, Sanna, Dhungana, Hiramani, Keksa-Goldsteine, Velta, Lemarchant, Sighild, Korhonen, Paula, Wojciechowski, Sara, Pollari, Eveliina, Valonen, Piia, Koponen, Juho, Takashima, Akihiko, Landreth, Gary, Goldsteins, Gundars, Malm, Tarja, Koistinaho, Jari, Kanninen, Katja M.
Publicado 2016

Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation

por Kolosowska, Natalia, Gotkiewicz, Maria, Dhungana, Hiramani, Giudice, Luca, Giugno, Rosalba, Box, Daphne, Huuskonen, Mikko T., Korhonen, Paula, Scoyni, Flavia, Kanninen, Katja M., Ylä-Herttuala, Seppo, Turunen, Tiia A., Turunen, Mikko P., Koistinaho, Jari, Malm, Tarja
Publicado 2020

A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease

por Stringer, Michael S., Lee, Hedok, Huuskonen, Mikko T., MacIntosh, Bradley J., Brown, Rosalind, Montagne, Axel, Atwi, Sarah, Ramirez, Joel, Jansen, Maurits A., Marshall, Ian, Black, Sandra E., Zlokovic, Berislav V., Benveniste, Helene, Wardlaw, Joanna M.
Publicado 2020

Magnetic resonance imaging of white matter response to diesel exhaust particles

por Chakhoyan, Ararat, Shkrkova, Kristina, Sizdahkhani, Saman, Huuskonen, Mikko T., Lamorie-Foote, Krista, Diaz, Arnold, Chen, Selena, Liu, Qinghai, D’Agostino, Carla, Zhang, Hongqiao, Mack, Wendy J., Sioutas, Constantinos, Finch, Caleb E., Zlokovic, Berislav, Mack, William J.
Publicado 2023

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

por Nikolakopoulou, Angeliki M., Montagne, Axel, Kisler, Kassandra, Dai, Zhonghua, Wang, Yaoming, Huuskonen, Mikko T., Sagare, Abhay P., Lazic, Divna, Sweeney, Melanie D., Kong, Pan, Wang, Min, Owens, Nelly Chuqui, Lawson, Erica J., Xie, Xiaochun, Zhao, Zhen, Zlokovic, Berislav V.
Publicado 2019

An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo

por Keuters, Meike Hedwig, Keksa-Goldsteine, Velta, Dhungana, Hiramani, Huuskonen, Mikko T., Pomeshchik, Yuriy, Savchenko, Ekaterina, Korhonen, Paula K., Singh, Yajuvinder, Wojciechowski, Sara, Lehtonen, Šárka, Kanninen, Katja M., Malm, Tarja, Sirviö, Jouni, Muona, Anu, Koistinaho, Milla, Goldsteins, Gundars, Koistinaho, Jari
Publicado 2021

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death

por Martiskainen, Henna, Paldanius, Kaisa M. A., Natunen, Teemu, Takalo, Mari, Marttinen, Mikael, Leskelä, Stina, Huber, Nadine, Mäkinen, Petra, Bertling, Enni, Dhungana, Hiramani, Huuskonen, Mikko, Honkakoski, Paavo, Hotulainen, Pirta, Rilla, Kirsi, Koistinaho, Jari, Soininen, Hilkka, Malm, Tarja, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2017

Air Pollution Particulate Matter Exposure and Chronic Cerebral Hypoperfusion and Measures of White Matter Injury in a Murine Model

por Liu, Qinghai, Shkirkova, Kristina, Lamorie-Foote, Krista, Connor, Michelle, Patel, Arati, Babadjouni, Robin, Huuskonen, Mikko, Montagne, Axel, Baertsch, Hans, Zhang, Hongqiao, Chen, Jiu-Chiuan, Mack, Wendy J., Walcott, Brian P., Zlokovic, Berislav V., Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E., Mack, William J.
Publicado 2021

Cu(II)(atsm) Attenuates Neuroinflammation

por Choo, Xin Yi, Liddell, Jeffrey R., Huuskonen, Mikko T., Grubman, Alexandra, Moujalled, Diane, Roberts, Jessica, Kysenius, Kai, Patten, Lauren, Quek, Hazel, Oikari, Lotta E., Duncan, Clare, James, Simon A., McInnes, Lachlan E., Hayne, David J., Donnelly, Paul S., Pollari, Eveliina, Vähätalo, Suvi, Lejavová, Katarína, Kettunen, Mikko I., Malm, Tarja, Koistinaho, Jari, White, Anthony R., Kanninen, Katja M.
Publicado 2018