Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation

por Hyle, Judith, Djekidel, Mohamed Nadhir, Williams, Justin, Wright, Shaela, Shao, Ying, Xu, Beisi, Li, Chunliang
Publicado 2023

Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping

por Hyle, Judith, Zhang, Yang, Wright, Shaela, Xu, Beisi, Shao, Ying, Easton, John, Tian, Liqing, Feng, Ruopeng, Xu, Peng, Li, Chunliang
Publicado 2019

Systematic characterization of the HOXA9 downstream targets in MLL-r leukemia by noncoding CRISPR screens

por Wright, Shaela, Zhao, Xujie, Rosikiewicz, Wojciech, Mryncza, Shelby, Hyle, Judith, Qi, Wenjie, Liu, Zhenling, Yi, Siqi, Cheng, Yong, Xu, Beisi, Li, Chunliang
Publicado 2023

Acute depletion of CTCF rewires genome-wide chromatin accessibility

por Xu, Beisi, Wang, Hong, Wright, Shaela, Hyle, Judith, Zhang, Yang, Shao, Ying, Niu, Mingming, Fan, Yiping, Rosikiewicz, Wojciech, Djekidel, Mohamed Nadhir, Peng, Junmin, Lu, Rui, Li, Chunliang
Publicado 2021

Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens

por Wright, Shaela, Hu, Jianzhong, Wang, Hong, Hyle, Judith, Zhang, Yang, Du, Guoqing, Konopleva, Marina Y., Kornblau, Steven M., Djekidel, Mohamed Nadhir, Rosikiewicz, Wojciech, Xu, Beisi, Lu, Rui, Yang, Jun J., Li, Chunliang
Publicado 2023

Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen

por Zhang, Hao, Zhang, Yang, Zhou, Xinyue, Wright, Shaela, Hyle, Judith, Zhao, Lianzhong, An, Jie, Zhao, Xujie, Shao, Ying, Xu, Beisi, Lee, Hyeong-Min, Chen, Taosheng, Zhou, Yang, Chen, Xiang, Lu, Rui, Li, Chunliang
Publicado 2020

Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X

por Liu, Yu, Li, Chunliang, Shen, Shuhong, Chen, Xiaolong, Szlachta, Karol, Edmonson, Michael N., Shao, Ying, Ma, Xiaotu, Hyle, Judith, Wright, Shaela, Ju, Bensheng, Rusch, Michael C., Liu, Yanling, Li, Benshang, Macias, Michael, Tian, Liqing, Easton, John, Qian, Maoxiang, Yang, Jun J., Hu, Shaoyan, Look, A. Thomas, Zhang, Jinghui
Publicado 2020