Tyrosine kinase signalling in breast cancer

por Hynes, Nancy E
Publicado 2000

Key signalling nodes in mammary gland development and cancer: Myc

por Hynes, Nancy E, Stoelzle, Tina
Publicado 2009

BAD: a good therapeutic target?

por Motoyama, Andrea B, Hynes, Nancy E
Publicado 2003

AXL/epidermal growth factor receptor (EGFR) complexes in breast cancer - culprits for resistance to EGFR inhibitors?

por Heideman, Marinus R, Hynes, Nancy E
Publicado 2013

Breast Cancer Patients Have Greatly Benefited from the Progress in Molecular Oncology

por Groner, Bernd L., Hynes, Nancy E.
Publicado 2016

c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland

por Stoelzle, Tina, Schwarb, Patrick, Trumpp, Andreas, Hynes, Nancy E
Publicado 2009

Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

por Schlange, Thomas, Matsuda, Yutaka, Lienhard, Susanne, Huber, Alexandre, Hynes, Nancy E
Publicado 2007

WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth

por Matsuda, Yutaka, Schlange, Thomas, Oakeley, Edward J, Boulay, Anne, Hynes, Nancy E
Publicado 2009

MHO1, an Evolutionarily Conserved Gene, Is Synthetic Lethal with PLC1; Mho1p Has a Role in Invasive Growth

por Schlatter, Ivan D., Meira, Maria, Ueberschlag, Vanessa, Hoepfner, Dominic, Movva, Rao, Hynes, Nancy E.
Publicado 2012

Transcriptional regulation of tenascin‐W by TGF‐beta signaling in the bone metastatic niche of breast cancer cells

por Chiovaro, Francesca, Martina, Enrico, Bottos, Alessia, Scherberich, Arnaud, Hynes, Nancy E., Chiquet‐Ehrismann, Ruth
Publicado 2015

Renal Memo1 Differentially Regulates the Expression of Vitamin D-Dependent Distal Renal Tubular Calcium Transporters

por Moor, Matthias B., Haenzi, Barbara, Legrand, Finola, Koesters, Robert, Hynes, Nancy E., Bonny, Olivier
Publicado 2018

Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glands

por Wang, Rui-An, Vadlamudi, Ratna K., Bagheri-Yarmand, Rozita, Beuvink, Iwan, Hynes, Nancy E., Kumar, Rakesh
Publicado 2003

ErbB2 Is Necessary for Induction of Carcinoma Cell Invasion by Erbb Family Receptor Tyrosine Kinases

por Spencer, Kathryn S.R., Graus-Porta, Diana, Leng, Jie, Hynes, Nancy E., Klemke, Richard L.
Publicado 2000

Memo interacts with c-Src to control Estrogen Receptor alpha sub-cellular localization

por Frei, Anna, MacDonald, Gwen, Lund, Ingrid, Gustafsson, Jan-Åke, Hynes, Nancy E., Nalvarte, Ivan
Publicado 2016

Combinatorial targeting of FGF and ErbB receptors blocks growth and metastatic spread of breast cancer models

por Issa, Amine, Gill, Jason W, Heideman, Marinus R, Sahin, Ozgur, Wiemann, Stefan, Dey, Julien H, Hynes, Nancy E
Publicado 2013

Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion

por Aceto, Nicola, Duss, Stephan, MacDonald, Gwen, Meyer, Dominique S, Roloff, Tim-C, Hynes, Nancy E, Bentires-Alj, Mohamed
Publicado 2012

Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice

por Moor, Matthias B., Ramakrishnan, Suresh K., Legrand, Finola, Bachtler, Matthias, Koesters, Robert, Hynes, Nancy E., Pasch, Andreas, Bonny, Olivier
Publicado 2020

Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models

por Bottos, Alessia, Gotthardt, Dagmar, Gill, Jason W., Gattelli, Albana, Frei, Anna, Tzankov, Alexandar, Sexl, Veronika, Wodnar-Filipowicz, Aleksandra, Hynes, Nancy E.
Publicado 2016

NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

por Ewald, Collin Yvès, Hourihan, John M, Bland, Monet S, Obieglo, Carolin, Katic, Iskra, Moronetti Mazzeo, Lorenza E, Alcedo, Joy, Blackwell, T Keith, Hynes, Nancy E
Publicado 2017

Memo Has a Novel Role in S1P Signaling and Crucial for Vascular Development

por Kondo, Shunya, Bottos, Alessia, Allegood, Jeremy C., Masson, Regis, Maurer, Francisca G., Genoud, Christel, Kaeser, Patrick, Huwiler, Andrea, Murakami, Masato, Spiegel, Sarah, Hynes, Nancy E.
Publicado 2014