Enantioselective Protein-Sterol Interactions Mediate Regulation of Both Prokaryotic and Eukaryotic Inward Rectifier K(+) Channels by Cholesterol

por D'Avanzo, Nazzareno, Hyrc, Krzysztof, Enkvetchakul, Decha, Covey, Douglas F., Nichols, Colin G.
Publicado 2011

Global Biochemical Profiling Identifies β-Hydroxypyruvate as a Potential Mediator of Type 2 Diabetes in Mice and Humans

por Zhang, Sheng, Wang, Songyan, Puhl, Matthew D., Jiang, Xuntian, Hyrc, Krzysztof L., Laciny, Erin, Wallendorf, Michael J., Pappan, Kirk L., Coyle, Joseph T., Wice, Burton M.
Publicado 2015

Preclinical PET imaging of glycoprotein non-metastatic melanoma B in triple negative breast cancer: feasibility of an antibody-based companion diagnostic agent

por Marquez-Nostra, Bernadette V., Lee, Supum, Laforest, Richard, Vitale, Laura, Nie, Xingyu, Hyrc, Krzysztof, Keler, Tibor, Hawthorne, Thomas, Hoog, Jeremy, Li, Shunqiang, Dehdashti, Farrokh, Ma, Cynthia X., Lapi, Suzanne E.
Publicado 2017

Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer’s Disease

por Zagorski, Karen, King, Olga, Hovakimyan, Armine, Petrushina, Irina, Antonyan, Tatevik, Chailyan, Gor, Ghazaryan, Manush, Hyrc, Krzysztof L., Chadarevian, Jean Paul, Davtyan, Hayk, Blurton-Jones, Mathew, Cribbs, David H., Agadjanyan, Michael G., Ghochikyan, Anahit
Publicado 2023

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

por Mayer, Allyson L., Higgins, Cassandra B., Heitmeier, Monique R., Kraft, Thomas E., Qian, Xia, Crowley, Jan R., Hyrc, Krzysztof L., Beatty, Wandy L., Yarasheski, Kevin E., Hruz, Paul W., DeBosch, Brian J.
Publicado 2016

Beta‐cell excitability and excitability‐driven diabetes in adult Zebrafish islets

por Emfinger, Christopher H., Lőrincz, Réka, Wang, Yixi, York, Nathaniel W., Singareddy, Soma S., Ikle, Jennifer M., Tryon, Robert C., McClenaghan, Conor, Shyr, Zeenat A., Huang, Yan, Reissaus, Christopher A., Meyer, Dirk, Piston, David W., Hyrc, Krzysztof, Remedi, Maria S., Nichols, Colin G.
Publicado 2019

TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis

por Ma, Xiucui, Rawnsley, David R., Kovacs, Attila, Islam, Moydul, Murphy, John T., Zhao, Chen, Kumari, Minu, Foroughi, Layla, Liu, Haiyan, Qi, Kevin, Diwan, Aaradhya, Hyrc, Krzysztof, Evans, Sarah, Satoh, Takashi, French, Brent A., Margulies, Kenneth B., Javaheri, Ali, Razani, Babak, Mann, Douglas L., Mani, Kartik, Diwan, Abhinav
Publicado 2021