P479: TREATMENT IS SHAPING CLONAL EVOLUTION AND RESISTANCE PATTERNS IN MURINE KMT2A-REARRANGED LEUKEMIA WITH SUBCLONAL FLT3N676K

por Falqués-Costa, Ton, Pilheden, Mattias, Zhang, Qirui, Ahlgren, Louise, Sturesson, Helena, Rönnstrand, Lars, Hyrenius-Wittsten, Axel, Kazi, Julhash U., Hagström-Andersson, Anna K.
Publicado 2023

Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance

por Åbacka, Hannah, Hansen, Jesper S., Huang, Peng, Venskutonytė, Raminta, Hyrenius-Wittsten, Axel, Poli, Giulio, Tuccinardi, Tiziano, Granchi, Carlotta, Minutolo, Filippo, Hagström-Andersson, Anna K., Lindkvist-Petersson, Karin
Publicado 2021

FLT3(N676K) drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

por Hyrenius-Wittsten, Axel, Pilheden, Mattias, Falqués-Costa, Antoni, Eriksson, Mia, Sturesson, Helena, Schneider, Pauline, Wander, Priscilla, Garcia-Ruiz, Cristian, Liu, Jian, Ågerstam, Helena, Hultquist, Anne, Lilljebjörn, Henrik, Stam, Ronald W., Järås, Marcus, Hagström-Andersson, Anna K.
Publicado 2019

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

por Lilljebjörn, Henrik, Henningsson, Rasmus, Hyrenius-Wittsten, Axel, Olsson, Linda, Orsmark-Pietras, Christina, von Palffy, Sofia, Askmyr, Maria, Rissler, Marianne, Schrappe, Martin, Cario, Gunnar, Castor, Anders, Pronk, Cornelis J. H., Behrendtz, Mikael, Mitelman, Felix, Johansson, Bertil, Paulsson, Kajsa, Andersson, Anna K., Fontes, Magnus, Fioretos, Thoas
Publicado 2016

De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

por Hyrenius-Wittsten, Axel, Pilheden, Mattias, Sturesson, Helena, Hansson, Jenny, Walsh, Michael P., Song, Guangchun, Kazi, Julhash U., Liu, Jian, Ramakrishan, Ramprasad, Garcia-Ruiz, Cristian, Nance, Stephanie, Gupta, Pankaj, Zhang, Jinghui, Rönnstrand, Lars, Hultquist, Anne, Downing, James R., Lindkvist-Petersson, Karin, Paulsson, Kajsa, Järås, Marcus, Gruber, Tanja A., Ma, Jing, Hagström-Andersson, Anna K.
Publicado 2018

Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia

por Pilheden, Mattias, Ahlgren, Louise, Hyrenius-Wittsten, Axel, Gonzalez-Pena, Veronica, Sturesson, Helena, Hansen Marquart, Hanne Vibeke, Lausen, Birgitte, Castor, Anders, Pronk, Cornelis Jan, Barbany, Gisela, Pokrovskaja Tamm, Katja, Fogelstrand, Linda, Lohi, Olli, Norén-Nyström, Ulrika, Asklin, Johanna, Chen, Yilun, Song, Guangchun, Walsh, Michael, Ma, Jing, Zhang, Jinghui, Saal, Lao H., Gawad, Charles, Hagström-Andersson, Anna K.
Publicado 2022