Exosomes as Carriers of Alzheimer's Amyloid-ß

por Yuyama, Kohei, Igarashi, Yasuyuki
Publicado 2017

4,8-Sphingadienine and 4-hydroxy-8-sphingenine activate ceramide production in the skin

por Shirakura, Yoshiyuki, Kikuchi, Kanako, Matsumura, Kenji, Mukai, Katsuyuki, Mitsutake, Susumu, Igarashi, Yasuyuki
Publicado 2012

VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes

por IGARASHI, YASUYUKI, CHOSA, NAOYUKI, SAWADA, SHUNSUKE, KONDO, HISATOMO, YAEGASHI, TAKASHI, ISHISAKI, AKIRA
Publicado 2016

Chemoenzymatically prepared konjac ceramide inhibits NGF-induced neurite outgrowth by a semaphorin 3A-like action

por Usuki, Seigo, Tamura, Noriko, Sakai, Shota, Tamura, Tomohiro, Mukai, Katsuyuki, Igarashi, Yasuyuki
Publicado 2015

Structure-dependent absorption of atypical sphingoid long-chain bases from digestive tract into lymph

por Mikami, Daisuke, Sakai, Shota, Nishimukai, Megumi, Yuyama, Kohei, Mukai, Katsuyuki, Igarashi, Yasuyuki
Publicado 2021

Ceramide Metabolism Regulated by Sphingomyelin Synthase 2 Is Associated with Acquisition of Chemoresistance via Exosomes in Human Leukemia Cells

por Taniguchi, Makoto, Nagaya, Shingo, Yuyama, Kohei, Kotani, Ai, Igarashi, Yasuyuki, Okazaki, Toshiro
Publicado 2022

Hetero-oligomeric interactions of an ELOVL4 mutant protein: implications in the molecular mechanism of Stargardt-3 macular dystrophy

por Okuda, Ayaka, Naganuma, Tatsuro, Ohno, Yusuke, Abe, Kensuke, Yamagata, Maki, Igarashi, Yasuyuki, Kihara, Akio
Publicado 2010

Inositol Depletion Restores Vesicle Transport in Yeast Phospholipid Flippase Mutants

por Yamagami, Kanako, Yamamoto, Takaharu, Sakai, Shota, Mioka, Tetsuo, Sano, Takamitsu, Igarashi, Yasuyuki, Tanaka, Kazuma
Publicado 2015

Neurite Outgrowth and Morphological Changes Induced by 8-trans Unsaturation of Sphingadienine in kCer Molecular Species

por Usuki, Seigo, Tamura, Noriko, Tamura, Tomohiro, Tanji, Kunikazu, Mikami, Daisuke, Mukai, Katsuyuki, Igarashi, Yasuyuki
Publicado 2019

Konjac Ceramide (kCer)-Mediated Signal Transduction of the Sema3A Pathway Promotes HaCaT Keratinocyte Differentiation

por Usuki, Seigo, Tamura, Noriko, Tamura, Tomohiro, Yuyama, Kohei, Mikami, Daisuke, Mukai, Katsuyuki, Igarashi, Yasuyuki
Publicado 2022

Immuno-digital invasive cleavage assay for analyzing Alzheimer’s amyloid ß-bound extracellular vesicles

por Yuyama, Kohei, Sun, Hui, Igarashi, Yasuyuki, Monde, Kenji, Hirase, Takumi, Nakayama, Masato, Makino, Yoichi
Publicado 2022

Blood-brain barrier permeability analysis of plant ceramides

por Eguchi, Koichi, Mikami, Daisuke, Sun, Hui, Tsumita, Takuya, Takahashi, Kaori, Mukai, Katsuyuki, Yuyama, Kohei, Igarashi, Yasuyuki
Publicado 2020

Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation

por Mizutani, Yukiko, Sun, Hui, Ohno, Yusuke, Sassa, Takayuki, Wakashima, Takeshi, Obara, Mari, Yuyama, Kohei, Kihara, Akio, Igarashi, Yasuyuki
Publicado 2013

Establishment of mesenchymal stem cell lines derived from the bone marrow of green fluorescent protein-transgenic mice exhibiting a diversity in intracellular transforming growth f...

por SAWADA, SHUNSUKE, CHOSA, NAOYUKI, TAKIZAWA, NAOKI, YOKOTA, JUN, IGARASHI, YASUYUKI, TOMODA, KOICHI, KONDO, HISATOMO, YAEGASHI, TAKASHI, ISHISAKI, AKIRA
Publicado 2016

Plant sphingolipids promote extracellular vesicle release and alleviate amyloid-β pathologies in a mouse model of Alzheimer’s disease

por Yuyama, Kohei, Takahashi, Kaori, Usuki, Seigo, Mikami, Daisuke, Sun, Hui, Hanamatsu, Hisatoshi, Furukawa, Junichi, Mukai, Katsuyuki, Igarashi, Yasuyuki
Publicado 2019

Evaluation of Plant Ceramide Species-Induced Exosome Release from Neuronal Cells and Exosome Loading Using Deuterium Chemistry

por Murai, Yuta, Honda, Takumi, Yuyama, Kohei, Mikami, Daisuke, Eguchi, Koichi, Ukawa, Yuichi, Usuki, Seigo, Igarashi, Yasuyuki, Monde, Kenji
Publicado 2022

Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus

por Taniguchi, Makoto, Tasaki, Takafumi, Ninomiya, Hideaki, Ueda, Yoshibumi, Kuremoto, Koh-ichi, Mitsutake, Susumu, Igarashi, Yasuyuki, Okazaki, Toshiro, Takegami, Tsutomu
Publicado 2016

Phytoceramide and sphingoid bases derived from brewer's yeast Saccharomyces pastorianus activate peroxisome proliferator-activated receptors

por Murakami, Itsuo, Wakasa, Yukari, Yamashita, Shinji, Kurihara, Toshio, Zama, Kota, Kobayashi, Naoyuki, Mizutani, Yukiko, Mitsutake, Susumu, Shigyo, Tatsuro, Igarashi, Yasuyuki
Publicado 2011

Konjac ceramide (kCer) regulates keratinocyte migration by Sema3A-like repulsion mechanism

por Usuki, Seigo, Tamura, Noriko, Tamura, Tomohiro, Higashiyama, Shigeki, Tanji, Kunikazu, Mitsutake, Susumu, Inoue, Asuka, Aoki, Junken, Mukai, Katsuyuki, Igarashi, Yasuyuki
Publicado 2019

Imaging Mass Spectrometry Reveals Acyl-Chain- and Region-Specific Sphingolipid Metabolism in the Kidneys of Sphingomyelin Synthase 2-Deficient Mice

por Sugimoto, Masayuki, Wakabayashi, Masato, Shimizu, Yoichi, Yoshioka, Takeshi, Higashino, Kenichi, Numata, Yoshito, Okuda, Tomohiko, Zhao, Songji, Sakai, Shota, Igarashi, Yasuyuki, Kuge, Yuji
Publicado 2016