Two novel mechanisms for maintenance of stemness in mesenchymal stem cells: SCRG1/BST1 axis and cell–cell adhesion through N-cadherin()

por Chosa, Naoyuki, Ishisaki, Akira
Publicado 2018

The blocking of uPAR suppresses lipopolysaccharide‐induced inflammatory osteoclastogenesis and the resultant bone loss through attenuation of integrin β3/Akt pathway

por Kanno, Yosuke, Ishisaki, Akira, Miyashita, Mei, Matsuo, Osamu
Publicado 2016

uPA‐derived peptide, Å6 is involved in the suppression of lipopolysaccaride‐promoted inflammatory osteoclastogenesis and the resultant bone loss

por Kanno, Yosuke, Maruyama, Chihiro, Matsuda, Ayaka, Ishisaki, Akira
Publicado 2017

TGF-β1 induces N-cadherin expression by upregulating Sox9 expression and promoting its nuclear translocation in human oral squamous cell carcinoma cells

por Hirano, Taifu, Saito, Daishi, Yamada, Hiroyuki, Ishisaki, Akira, Kamo, Masaharu
Publicado 2020

Extracellular adenosine 5ʹ-diphosphate promotes MCP-1/CCL2 expression via the P2Y(13) purinergic receptor/ERK signaling axis in temporomandibular joint-derived mouse fibroblast-lik...

por Yokota, Seiji, Chosa, Naoyuki, Matsumoto, Shikino, Satoh, Kazuro, Ishisaki, Akira
Publicado 2022

Effects of apatite particle size in two apatite/collagen composites on the osteogenic differentiation profile of osteoblastic cells

por HATAKEYAMA, WATARU, TAIRA, MASAYUKI, CHOSA, NAOYUKI, KIHARA, HIDEMICHI, ISHISAKI, AKIRA, KONDO, HISATOMO
Publicado 2013

uPA Attenuated LPS-induced Inflammatory Osteoclastogenesis through the Plasmin/PAR-1/Ca(2+)/CaMKK/AMPK Axis

por Kanno, Yosuke, Ishisaki, Akira, Kawashita, Eri, Kuretake, Hiromi, Ikeda, Kanako, Matsuo, Osamu
Publicado 2016

VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes

por IGARASHI, YASUYUKI, CHOSA, NAOYUKI, SAWADA, SHUNSUKE, KONDO, HISATOMO, YAEGASHI, TAKASHI, ISHISAKI, AKIRA
Publicado 2016

Enhancement of Anti-Inflammatory and Osteogenic Abilities of Mesenchymal Stem Cells via Cell-to-Cell Adhesion to Periodontal Ligament-Derived Fibroblasts

por Suzuki, Keita, Chosa, Naoyuki, Sawada, Shunsuke, Takizawa, Naoki, Yaegashi, Takashi, Ishisaki, Akira
Publicado 2017

Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymal-epithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 path...

por Chiba, Takahiro, Ishisaki, Akira, Kyakumoto, Seiko, Shibata, Toshiyuki, Yamada, Hiroyuki, Kamo, Masaharu
Publicado 2017

Water-soluble factors eluated from surface pre-reacted glass-ionomer filler promote osteoblastic differentiation of human mesenchymal stem cells

por Nemoto, Akira, Chosa, Naoyuki, Kyakumoto, Seiko, Yokota, Seiji, Kamo, Masaharu, Noda, Mamoru, Ishisaki, Akira
Publicado 2018

SCRG1 suppresses LPS-induced CCL22 production through ERK1/2 activation in mouse macrophage Raw264.7 cells

por Inoue, Manabu, Yamada, Junko, Aomatsu-Kikuchi, Emiko, Satoh, Kazuro, Kondo, Hisatomo, Ishisaki, Akira, Chosa, Naoyuki
Publicado 2017

TGF-β-Operated Growth Inhibition and Translineage Commitment into Smooth Muscle Cells of Periodontal Ligament-Derived Endothelial Progenitor Cells through Smad- and p38 MAPK-Depend...

por Yoshida, Mariko, Okubo, Naoto, Chosa, Naoyuki, Hasegawa, Tomokazu, Ibi, Miho, Kamo, Masaharu, Kyakumoto, Seiko, Ishisaki, Akira
Publicado 2012

Fibroblast growth factor 2 inhibits the expression of stromal cell-derived factor 1α in periodontal ligament cells derived from human permanent teeth in vitro

por ASAKAWA, TAKEYOSHI, CHOSA, NAOYUKI, YOSHIMURA, YOSHITAKA, ASAKAWA, ASAMI, TANAKA, MITSURO, ISHISAKI, AKIRA, MITOME, MASATO, HASEGAWA, TOMOKAZU
Publicado 2011

PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner

por YOKOTA, JUN, CHOSA, NAOYUKI, SAWADA, SHUNSUKE, OKUBO, NAOTO, TAKAHASHI, NORIKO, HASEGAWA, TOMOKAZU, KONDO, HISATOMO, ISHISAKI, AKIRA
Publicado 2014

Zoledronic acid suppresses transforming growth factor-β-induced fibrogenesis by human gingival fibroblasts

por KOMATSU, YUKO, IBI, MIHO, CHOSA, NAOYUKI, KYAKUMOTO, SEIKO, KAMO, MASAHARU, SHIBATA, TOSHIYUKI, SUGIYAMA, YOSHIKI, ISHISAKI, AKIRA
Publicado 2016

ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint

por Yokota, Seiji, Chosa, Naoyuki, Kyakumoto, Seiko, Kimura, Hitomichi, Ibi, Miho, Kamo, Masaharu, Satoh, Kazuro, Ishisaki, Akira
Publicado 2017

Cell–cell interactions between monocytes/macrophages and synoviocyte-like cells promote inflammatory cell infiltration mediated by augmentation of MCP-1 production in temporomandib...

por Ibi, Miho, Horie, Sawa, Kyakumoto, Seiko, Chosa, Naoyuki, Yoshida, Mariko, Kamo, Masaharu, Ohtsuka, Masato, Ishisaki, Akira
Publicado 2018

Receptor tyrosine kinase ligands and inflammatory cytokines cooperatively suppress the fibrogenic activity in temporomandibular-joint-derived fibroblast-like synoviocytes via mitog...

por Matsumoto, Shikino, Yokota, Seiji, Chosa, Naoyuki, Kyakumoto, Seiko, Kimura, Hitomichi, Kamo, Masaharu, Satoh, Kazuro, Ishisaki, Akira
Publicado 2020

Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells

por Aomatsu, Emiko, Takahashi, Noriko, Sawada, Shunsuke, Okubo, Naoto, Hasegawa, Tomokazu, Taira, Masayuki, Miura, Hiroyuki, Ishisaki, Akira, Chosa, Naoyuki
Publicado 2014