Distinct role of CD8 cells and CD4 cells in antitumor immunity triggered by cell apoptosis using a Herpes simplex virus thymidine kinase/ganciclovir system

por Umegaki, Sho, Shirota, Hidekazu, Kasahara, Yuki, Iwasaki, Tomoyuki, Ishioka, Chikashi
Publicado 2023

Possible Role of Bent Structure of Methylated Lithocholic Acid on Artificial and Plasma Membranes

por Iwasaki, Tomoyuki, Endo, Nobuyuki, Nakayama, Yuta, Kamei, Toshiyuki, Shimanouchi, Toshinori, Nakamura, Hidemi, Hayashi, Keita
Publicado 2022

Development of tumor-specific caffeine-potentiated chemotherapy using a novel drug delivery system with Span 80 nano-vesicles

por NAKATA, HIROSHI, MIYAZAKI, TATSUHIKO, IWASAKI, TOMOYUKI, NAKAMURA, ATSUSHI, KIDANI, TERUKI, SAKAYAMA, KENSHI, MASUMOTO, JUNYA, MIURA, HIROMASA
Publicado 2015

Applications of reconstituted inflammasomes in a cell-free system to drug discovery and elucidation of the pathogenesis of autoinflammatory diseases

por Kaneko, Naoe, Iwasaki, Tomoyuki, Ito, Yuki, Takeda, Hiroyuki, Sawasaki, Tatsuya, Morikawa, Shinnosuke, Nakano, Naoko, Kurata, Mie, Masumoto, Junya
Publicado 2017

Nod2-Nodosome in a Cell-Free System: Implications in Pathogenesis and Drug Discovery for Blau Syndrome and Early-Onset Sarcoidosis

por Iwasaki, Tomoyuki, Kaneko, Naoe, Ito, Yuki, Takeda, Hiroyuki, Sawasaki, Tatsuya, Heike, Toshio, Migita, Kiyoshi, Agematsu, Kazunaga, Kawakami, Atsushi, Morikawa, Shinnosuke, Mokuda, Sho, Kurata, Mie, Masumoto, Junya
Publicado 2016

Effect of tofogliflozin and pioglitazone on hepatic steatosis in non-alcoholic fatty liver disease patients with type 2 diabetes mellitus: A randomized, open-label pilot study (ToP...

por Ozaki, Anna, Yoneda, Masato, Kessoku, Takaomi, Iwaki, Michihiro, Kobayashi, Takashi, Honda, Yasushi, Ogawa, Yuji, Imajo, Kento, Sakai, Eiji, Taguri, Masataka, Yamanaka, Takeharu, Iwasaki, Tomoyuki, Kurihashi, Takeo, Saito, Satoru, Nakajima, Atsushi
Publicado 2019

Comparing the effects of tofogliflozin and pioglitazone in non-alcoholic fatty liver disease patients with type 2 diabetes mellitus (ToPiND study): a randomized prospective open-la...

por Yoneda, Masato, Honda, Yasushi, Ogawa, Yuji, Kessoku, Takaomi, Kobayashi, Takashi, Imajo, Kento, Ozaki, Anna, Nogami, Asako, Taguri, Masataka, Yamanaka, Takeharu, Kirikoshi, Hiroyuki, Iwasaki, Tomoyuki, Kurihashi, Takeo, Saito, Satoru, Nakajima, Atsushi
Publicado 2021

Periodontal Treatment and Usual Care for Nonalcoholic Fatty Liver Disease: A Multicenter, Randomized Controlled Trial

por Kamata, Yohei, Kessoku, Takaomi, Shimizu, Tomoko, Sato, Satsuki, Kobayashi, Takashi, Kurihashi, Takeo, Morozumi, Toshiya, Iwasaki, Tomoyuki, Takashiba, Shogo, Hatanaka, Kazu, Hamada, Nobushiro, Kodama, Toshiro, Higurashi, Takuma, Taguri, Masataka, Yoneda, Masato, Usuda, Haruki, Wada, Koichiro, Nakajima, Atsushi, Minabe, Masato
Publicado 2022

Efficacy and safety of PERIOdontal treatment versus usual care for Nonalcoholic liver disease: protocol of the PERION multicenter, two-arm, open-label, randomized trial

por Kamata, Yohei, Kessoku, Takaomi, Shimizu, Tomoko, Kobayashi, Takashi, Kurihashi, Takeo, Sato, Satsuki, Kuraji, Syotaro, Aoyama, Norio, Iwasaki, Tomoyuki, Takashiba, Shogo, Hamada, Nobushiro, Kodama, Toshiro, Tamura, Toshiyuki, Ino, Satoshi, Higurashi, Takuma, Taguri, Masataka, Yamanaka, Takeharu, Yoneda, Masato, Usuda, Haruki, Wada, Koichiro, Nakajima, Atsushi, Minabe, Masato
Publicado 2020

Rationale and design of a multicenter, single-group, open-label trial aiming at investigating the effectiveness of elobixibat for loss of defecation desire in patients with chronic...

por Yamamoto, Atsushi, Kessoku, Takaomi, Tanaka, Kosuke, Takahashi, Kota, Kasai, Yuki, Ozaki, Anna, Iwaki, Michihiro, Kobayashi, Takashi, Yoshihara, Tsutomu, Misawa, Noboru, Ohkuma, Kanji, Fuyuki, Akiko, Higurashi, Takuma, Hosono, Kunihiro, Yoneda, Masato, Iwasaki, Tomoyuki, Kurihashi, Takeo, Nakatogawa, Machiko, Suzuki, Ayao, Taguri, Masataka, Oyamada, Shunsuke, Ariyoshi, Keisuke, Kobayashi, Noritoshi, Ichikawa, Yasushi, Nakajima, Atsushi
Publicado 2022

Rationale and design of a multicentre, 12-week, randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated trial to investigate the efficacy and safety of...

por Tanaka, Kosuke, Kessoku, Takaomi, Yamamoto, Atsushi, Takahashi, Kota, Kasai, Yuki, Ozaki, Anna, Iwaki, Michihiro, Kobayashi, Takashi, Yoshihara, Tsutomu, Misawa, Noboru, Kato, Takayuki, Arimoto, Jun, Fuyuki, Akiko, Sakai, Eiji, Higurashi, Takuma, Chiba, Hideyuki, Hosono, Kunihiro, Yoneda, Masato, Iwasaki, Tomoyuki, Kurihashi, Takeo, Nakatogawa, Machiko, Suzuki, Ayao, Taguri, Masataka, Oyamada, Shunsuke, Ariyoshi, Keisuke, Kobayashi, Noritoshi, Ichikawa, Yasushi, Nakajima, Atsushi
Publicado 2022

Efficacy and Safety of Adding Sitagliptin in Type 2 Diabetes Patients on Insulin: Age-Stratified Comparison at One Year in the ASSIST-K Study

por Takai, Masahiko, Ishikawa, Masashi, Maeda, Hajime, Kanamori, Akira, Kubota, Akira, Amemiya, Hikaru, Iizuka, Takashi, Iemitsu, Kotaro, Iwasaki, Tomoyuki, Uehara, Goro, Umezawa, Shinichi, Obana, Mitsuo, Kaneshige, Hideaki, Kaneshiro, Mizuki, Kawata, Takehiro, Sasai, Nobuo, Saito, Tatsuya, Takuma, Tetsuo, Takeda, Hiroshi, Tanaka, Keiji, Nakajima, Shigeru, Hoshino, Kazuhiko, Honda, Shin, Machimura, Hideo, Matoba, Kiyokazu, Minagawa, Fuyuki, Minami, Nobuaki, Miyairi, Yukiko, Mokubo, Atsuko, Motomiya, Tetsuya, Waseda, Manabu, Miyakawa, Masaaki, Terauchi, Yasuo, Tanaka, Yasushi, Matsuba, Ikuro
Publicado 2019

Factors Predicting Therapeutic Efficacy of Combination Treatment With Sitagliptin and Insulin in Type 2 Diabetic Patients: The ASSIST-K Study

por Ishikawa, Masashi, Takai, Masahiko, Maeda, Hajime, Kanamori, Akira, Kubota, Akira, Amemiya, Hikaru, Iizuka, Takashi, Iemitsu, Kotaro, Iwasaki, Tomoyuki, Uehara, Goro, Umezawa, Shinichi, Obana, Mitsuo, Kaneshige, Hideaki, Kaneshiro, Mizuki, Kawata, Takehiro, Sasai, Nobuo, Saito, Tatsuya, Takuma, Tetsuo, Takeda, Hiroshi, Tanaka, Keiji, Tsurui, Nobuaki, Nakajima, Shigeru, Hoshino, Kazuhiko, Honda, Shin, Machimura, Hideo, Matoba, Kiyokazu, Minagawa, Fuyuki, Minami, Nobuaki, Miyairi, Yukiko, Mokubo, Atsuko, Motomiya, Tetsuya, Waseda, Manabu, Miyakawa, Masaaki, Naka, Yoshikazu, Terauchi, Yasuo, Tanaka, Yasushi, Matsuba, Ikuro
Publicado 2015

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

por Kikuchi, Koichi, Saigusa, Daisuke, Kanemitsu, Yoshitomi, Matsumoto, Yotaro, Thanai, Paxton, Suzuki, Naoto, Mise, Koki, Yamaguchi, Hiroaki, Nakamura, Tomohiro, Asaji, Kei, Mukawa, Chikahisa, Tsukamoto, Hiroki, Sato, Toshihiro, Oikawa, Yoshitsugu, Iwasaki, Tomoyuki, Oe, Yuji, Tsukimi, Tomoya, Fukuda, Noriko N., HO, Hsin-Jung, Nanto-Hara, Fumika, Ogura, Jiro, Saito, Ritsumi, Nagao, Shizuko, Ohsaki, Yusuke, Shimada, Satoshi, Suzuki, Takehiro, Toyohara, Takafumi, Mishima, Eikan, Shima, Hisato, Akiyama, Yasutoshi, Akiyama, Yukako, Ichijo, Mariko, Matsuhashi, Tetsuro, Matsuo, Akihiro, Ogata, Yoshiaki, Yang, Ching-Chin, Suzuki, Chitose, Breeggemann, Matthew C., Heymann, Jurgen, Shimizu, Miho, Ogawa, Susumu, Takahashi, Nobuyuki, Suzuki, Takashi, Owada, Yuji, Kure, Shigeo, Mano, Nariyasu, Soga, Tomoyoshi, Wada, Takashi, Kopp, Jeffrey B., Fukuda, Shinji, Hozawa, Atsushi, Yamamoto, Masayuki, Ito, Sadayoshi, Wada, Jun, Tomioka, Yoshihisa, Abe, Takaaki
Publicado 2019