G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells

por Di Somma, Sarah, Amato, Jussara, Iaccarino, Nunzia, Pagano, Bruno, Randazzo, Antonio, Portella, Giuseppe, Malfitano, Anna Maria
Publicado 2019

Development of an Optimized Protocol for NMR Metabolomics Studies of Human Colon Cancer Cell Lines and First Insight from Testing of the Protocol Using DNA G-Quadruplex Ligands as...

por Lauri, Ilaria, Savorani, Francesco, Iaccarino, Nunzia, Zizza, Pasquale, Pavone, Luigi Michele, Novellino, Ettore, Engelsen, Søren Balling, Randazzo, Antonio
Publicado 2016

Ancient Danish Apple Cultivars—A Comprehensive Metabolite and Sensory Profiling of Apple Juices

por Iaccarino, Nunzia, Varming, Camilla, Agerlin Petersen, Mikael, Viereck, Nanna, Schütz, Birk, Toldam-Andersen, Torben Bo, Randazzo, Antonio, Balling Engelsen, Søren
Publicado 2019

Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells

por Amato, Jussara, Miglietta, Giulia, Morigi, Rita, Iaccarino, Nunzia, Locatelli, Alessandra, Leoni, Alberto, Novellino, Ettore, Pagano, Bruno, Capranico, Giovanni, Randazzo, Antonio
Publicado 2020

Effects of Sequence and Base Composition on the CD and TDS Profiles of i‐DNA

por Iaccarino, Nunzia, Cheng, Mingpan, Qiu, Dehui, Pagano, Bruno, Amato, Jussara, Di Porzio, Anna, Zhou, Jun, Randazzo, Antonio, Mergny, Jean‐Louis
Publicado 2021

Targeting of Telomeric Repeat-Containing RNA G-Quadruplexes: From Screening to Biophysical and Biological Characterization of a New Hit Compound

por Marzano, Simona, Pagano, Bruno, Iaccarino, Nunzia, Di Porzio, Anna, De Tito, Stefano, Vertecchi, Eleonora, Salvati, Erica, Randazzo, Antonio, Amato, Jussara
Publicado 2021

Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study

por Iaccarino, Nunzia, Amato, Jussara, Pagano, Bruno, Di Porzio, Anna, Micucci, Matteo, Bolelli, Luca, Aldini, Rita, Novellino, Ettore, Budriesi, Roberta, Randazzo, Antonio
Publicado 2019

Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex

por Amato, Jussara, Iaccarino, Nunzia, Pagano, Bruno, Morigi, Rita, Locatelli, Alessandra, Leoni, Alberto, Rambaldi, Mirella, Zizza, Pasquale, Biroccio, Annamaria, Novellino, Ettore, Randazzo, Antonio
Publicado 2014

Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives

por Ogloblina, Anna M., Iaccarino, Nunzia, Capasso, Domenica, Di Gaetano, Sonia, Garzarella, Emanuele U., Dolinnaya, Nina G., Yakubovskaya, Marianna G., Pagano, Bruno, Amato, Jussara, Randazzo, Antonio
Publicado 2020

Over-Expressed GATA-1(S), the Short Isoform of the Hematopoietic Transcriptional Factor GATA-1, Inhibits Ferroptosis in K562 Myeloid Leukemia Cells by Preventing Lipid Peroxidation

por Trombetti, Silvia, Iaccarino, Nunzia, Riccio, Patrizia, Sessa, Raffaele, Catapano, Rosa, Salvatore, Marcella, Luka, Stelina, de Nicola, Sergio, Izzo, Paola, Roperto, Sante, Maddalena, Pasqualino, Randazzo, Antonio, Grosso, Michela
Publicado 2023

Common G-Quadruplex Binding Agents Found to Interact With i-Motif-Forming DNA: Unexpected Multi-Target-Directed Compounds

por Pagano, Alessia, Iaccarino, Nunzia, Abdelhamid, Mahmoud A. S., Brancaccio, Diego, Garzarella, Emanuele U., Di Porzio, Anna, Novellino, Ettore, Waller, Zoë A. E., Pagano, Bruno, Amato, Jussara, Randazzo, Antonio
Publicado 2018

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

por Amato, Jussara, Cerofolini, Linda, Brancaccio, Diego, Giuntini, Stefano, Iaccarino, Nunzia, Zizza, Pasquale, Iachettini, Sara, Biroccio, Annamaria, Novellino, Ettore, Rosato, Antonio, Fragai, Marco, Luchinat, Claudio, Randazzo, Antonio, Pagano, Bruno
Publicado 2019

Synthesis and Characterization of Bis-Triazolyl-Pyridine Derivatives as Noncanonical DNA-Interacting Compounds

por Di Porzio, Anna, Galli, Ubaldina, Amato, Jussara, Zizza, Pasquale, Iachettini, Sara, Iaccarino, Nunzia, Marzano, Simona, Santoro, Federica, Brancaccio, Diego, Carotenuto, Alfonso, De Tito, Stefano, Biroccio, Annamaria, Pagano, Bruno, Tron, Gian Cesare, Randazzo, Antonio
Publicado 2021

Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics

por Chianese, Ugo, Papulino, Chiara, Passaro, Eugenia, Evers, Tom MJ., Babaei, Mehrad, Toraldo, Antonella, De Marchi, Tommaso, Niméus, Emma, Carafa, Vincenzo, Nicoletti, Maria Maddalena, Del Gaudio, Nunzio, Iaccarino, Nunzia, Randazzo, Antonio, Rotili, Dante, Mai, Antonello, Cappabianca, Salvatore, Mashaghi, Alireza, Ciardiello, Fortunato, Altucci, Lucia, Benedetti, Rosaria
Publicado 2022