Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds

por Luxenburger, Andreas, Schmidt, Dorian, Ianes, Chiara, Pichlo, Christian, Krüger, Marc, von Drathen, Thorsten, Brunstein, Elena, Gainsford, Graeme J., Baumann, Ulrich, Knippschild, Uwe, Peifer, Christian
Publicado 2019

Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK

por Halekotte, Jakob, Witt, Lydia, Ianes, Chiara, Krüger, Marc, Bührmann, Mike, Rauh, Daniel, Pichlo, Christian, Brunstein, Elena, Luxenburger, Andreas, Baumann, Ulrich, Knippschild, Uwe, Bischof, Joachim, Peifer, Christian
Publicado 2017

Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines

por Liu, Congxing, Witt, Lydia, Ianes, Chiara, Bischof, Joachim, Bammert, Marie-Thérèse, Baier, Joana, Kirschner, Stefan, Henne-Bruns, Doris, Xu, Pengfei, Kornmann, Marko, Peifer, Christian, Knippschild, Uwe
Publicado 2019