Extending the applicability of P3D for structure determination of small molecules

por Ibáñez de Opakua, Alain, Zweckstetter, Markus
Publicado 2021

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

por Savastano, Adriana, Ibáñez de Opakua, Alain, Rankovic, Marija, Zweckstetter, Markus
Publicado 2020

Contributions of the N‐terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA‐induced phase separation

por Zachrdla, Milan, Savastano, Adriana, Ibáñez de Opakua, Alain, Cima‐Omori, Maria‐Sol, Zweckstetter, Markus
Publicado 2022

Determination of Complex Small‐Molecule Structures Using Molecular Alignment Simulation

por Ibáñez de Opakua, Alain, Klama, Frederik, Ndukwe, Ikenna E., Martin, Gary E., Williamson, R. Thomas, Zweckstetter, Markus
Publicado 2020

Molecular Basis of Small-Molecule Binding to α-Synuclein

por Robustelli, Paul, Ibanez-de-Opakua, Alain, Campbell-Bezat, Cecily, Giordanetto, Fabrizio, Becker, Stefan, Zweckstetter, Markus, Pan, Albert C., Shaw, David E.
Publicado 2022

The metastasis suppressor KISS1 is an intrinsically disordered protein slightly more extended than a random coil

por Ibáñez de Opakua, Alain, Merino, Nekane, Villate, Maider, Cordeiro, Tiago N., Ormaza, Georgina, Sánchez-Carbayo, Marta, Diercks, Tammo, Bernadó, Pau, Blanco, Francisco J.
Publicado 2017

Molecular interactions of FG nucleoporin repeats at high resolution

por Ibáñez de Opakua, Alain, Geraets, James A., Frieg, Benedikt, Dienemann, Christian, Savastano, Adriana, Rankovic, Marija, Cima-Omori, Maria-Sol, Schröder, Gunnar F., Zweckstetter, Markus
Publicado 2022

Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization

por Dominguez-Meijide, Antonio, Vasili, Eftychia, König, Annekatrin, Cima-Omori, Maria-Sol, Ibáñez de Opakua, Alain, Leonov, Andrei, Ryazanov, Sergey, Zweckstetter, Markus, Griesinger, Christian, Outeiro, Tiago F.
Publicado 2020

Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer

por Zhao, Jingyi, DiGiacomo, Vincent, Ferreras-Gutierrez, Mariola, Dastjerdi, Shiva, Ibáñez de Opakua, Alain, Park, Jong-Chan, Luebbers, Alex, Chen, Qingyan, Beeler, Aaron, Blanco, Francisco J., Garcia-Marcos, Mikel
Publicado 2023

A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity

por Kumar, Senthil T., Mahul-Mellier, Anne-Laure, Hegde, Ramanath Narayana, Rivière, Gwladys, Moons, Rani, Ibáñez de Opakua, Alain, Magalhães, Pedro, Rostami, Iman, Donzelli, Sonia, Sobott, Frank, Zweckstetter, Markus, Lashuel, Hilal A.
Publicado 2022

TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

por Hoffmann, Saskia, Smedegaard, Stine, Nakamura, Kyosuke, Mortuza, Gulnahar B., Räschle, Markus, Ibañez de Opakua, Alain, Oka, Yasuyoshi, Feng, Yunpeng, Blanco, Francisco J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon, Mailand, Niels
Publicado 2016

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage

por Rosado-Ramos, Rita, Poças, Gonçalo M., Marques, Daniela, Foito, Alexandre, M. Sevillano, David, Lopes-da-Silva, Mafalda, Gonçalves, Luís G., Menezes, Regina, Ottens, Marcel, Stewart, Derek, Ibáñez de Opakua, Alain, Zweckstetter, Markus, Seabra, Miguel C., Mendes, César S., Outeiro, Tiago Fleming, Domingos, Pedro M., Santos, Cláudia N.
Publicado 2023