Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity

por Ibba, Salome' V., Ghonim, Mohamed A., Pyakurel, Kusma, Lammi, Matthew R., Mishra, Anil, Boulares, A. Hamid
Publicado 2016

Promotion of a synthetic degradation of activated STAT6 by PARP-1 inhibition: roles of poly(ADP-ribosyl)ation, calpains and autophagy

por Wang, Jeffrey, Ghonim, Mohamed A., Ibba, Salome V., Luu, Hanh H., Aydin, Yucel, Greer, Peter A., Boulares, A. Hamid
Publicado 2022

Thiazolides Elicit Anti-Viral Innate Immunity and Reduce HIV Replication

por Trabattoni, Daria, Gnudi, Federica, Ibba, Salomè V., Saulle, Irma, Agostini, Simone, Masetti, Michela, Biasin, Mara, Rossignol, Jean-Francois, Clerici, Mario
Publicado 2016

Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway

por Ghonim, Mohamed A., Wang, Jeffrey, Ibba, Salome V., Luu, Hanh H., Pyakurel, Kusma, Benslimane, Ilyes, Mousa, Shaker, Boulares, A. Hamid
Publicado 2018

Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

por Ghonim, Mohamed A, Ibba, Salome V, Tarhuni, Abdelmetalab F, Errami, Youssef, Luu, Hanh H, Dean, Matthew J, El-Bahrawy, Ali H, Wyczechowska, Dorota, Benslimane, Ilyes A, Del Valle, Luis, Al-Khami, Amir A, Ochoa, Augusto C, Boulares, A Hamid
Publicado 2021

Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses

por Monticone, Giulia, Huang, Zhi, Csibi, Fred, Leit, Silvana, Ciccone, David, Champhekar, Ameya S., Austin, Jermaine E., Ucar, Deniz A., Hossain, Fokhrul, Ibba, Salome V., Boulares, A. Hamid, Carpino, Nicholas, Xu, Keli, Majumder, Samarpan, Osborne, Barbara A., Loh, Christine, Miele, Lucio
Publicado 2022

PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function

por Ghonim, Mohamed A, Pyakurel, Kusma, Ibba, Salome V, Al-Khami, Amir A, Wang, Jeffrey, Rodriguez, Paulo, Rady, Hamada F, El-Bahrawy, Ali H, Lammi, Matthew R, Mansy, Moselhy S, Al-Ghareeb, Kamel, Ramsay, Alistair, Ochoa, Augusto, Naura, Amarjit S, Boulares, A Hamid
Publicado 2015

PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice

por Ghonim, Mohamed A., Pyakurel, Kusma, Ibba, Salome V., Wang, Jeffrey, Rodriguez, Paulo, Al-Khami, Amir A., Lammi, Matthew R., Kim, Hogyoung, Zea, Arnold H., Davis, Christian, Okpechi, Samuel, Wyczechowska, Dorota, Al-Ghareeb, Kamel, Mansy, Moselhy S., Ochoa, Augusto, Naura, Amarjit S., Boulares, A. Hamid
Publicado 2015