Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration

por Waksmunski, Andrea R., Grunin, Michelle, Kinzy, Tyler G., Igo, Robert P., Haines, Jonathan L., Cooke Bailey, Jessica N.
Publicado 2019

Statistical driver genes as a means to uncover missing heritability for age-related macular degeneration

por Waksmunski, Andrea R., Grunin, Michelle, Kinzy, Tyler G., Igo, Robert P., Haines, Jonathan L., Cooke Bailey, Jessica N.
Publicado 2020

Density-based clustering in haplotype analysis for association mapping

por Igo, Robert P, Londono, Douglas, Miller, Katherine, Parrado, Antonio R, Quade, Shannon RE, Sinha, Moumita, Kim, Sulgi, Won, Sungho, Li, Jing, Goddard, Katrina AB
Publicado 2007

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ɛ4

por Margeta, Milica A., Letcher, Sophia M., Igo, Robert P., Cooke Bailey, Jessica N., Pasquale, Louis R., Haines, Jonathan L., Butovsky, Oleg, Wiggs, Janey L.
Publicado 2020

AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection

por Papp, Audrey C., Azad, Abul K., Pietrzak, Maciej, Williams, Amanda, Handelman, Samuel K., Igo, Robert P., Stein, Catherine M., Hartmann, Katherine, Schlesinger, Larry S., Sadee, Wolfgang
Publicado 2018

Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19

por Lillvis, John H, Kyo, Yoshiki, Tromp, Gerard, Lenk, Guy M, Li, Ming, Lu, Qing, Igo, Robert P, Sakalihasan, Natzi, Ferrell, Robert E, Schworer, Charles M, Gatalica, Zoran, Land, Susan, Kuivaniemi, Helena
Publicado 2011

Differing Roles for TCF4 and COL8A2 in Central Corneal Thickness and Fuchs Endothelial Corneal Dystrophy

por Igo, Robert P., Kopplin, Laura J., Joseph, Peronne, Truitt, Barbara, Fondran, Jeremy, Bardenstein, David, Aldave, Anthony J., Croasdale, Christopher R., Price, Marianne O., Rosenwasser, Miriam, Lass, Jonathan H., Iyengar, Sudha K.
Publicado 2012

Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda

por Ma, Ningning, Zalwango, Sarah, Malone, LaShaunda L, Nsereko, Mary, Wampande, Eddie M, Thiel, Bonnie A, Okware, Brenda, Igo, Robert P, Joloba, Moses L, Mupere, Ezekiel, Mayanja-Kizza, Harriet, Boom, W Henry, Stein, Catherine M
Publicado 2014

Fine-mapping Analysis of a Chromosome 2 Region Linked to Resistance to Mycobacterium tuberculosis Infection in Uganda Reveals Potential Regulatory Variants

por Igo, Robert P., Hall, Noémi B., Malone, LaShaunda L., Hall, Jacob B., Truitt, Barbara, Qiu, Feiyou, Tao, Li, Mupere, Ezekiel, Schnell, Audrey, Hawn, Thomas R., Bush, William S., Joloba, Moses, Boom, W. Henry, Stein, Catherine M.
Publicado 2018

Practical Barriers and Ethical Challenges in Genetic Data Sharing

por Simpson, Claire L., Goldenberg, Aaron J., Culverhouse, Rob, Daley, Denise, Igo, Robert P., Jarvik, Gail P., Mandal, Diptasri M., Mascalzoni, Deborah, Montgomery, Courtney Gray, Pierce, Brandon L., Plaetke, Rosemarie, Shete, Sanjay, Goddard, Katrina A. B., Stein, Catherine M.
Publicado 2014

Rare variants and loci for age-related macular degeneration in the Ohio and Indiana Amish

por Waksmunski, Andrea R., Igo, Robert P., Song, Yeunjoo E., Cooke Bailey, Jessica N., Laux, Renee, Fuzzell, Denise, Fuzzell, Sarada, Adams, Larry D., Caywood, Laura, Prough, Michael, Stambolian, Dwight, Scott, William K., Pericak-Vance, Margaret A., Haines, Jonathan L.
Publicado 2019

Association between genes regulating neural pathways for quantitative traits of speech and language disorders

por Benchek, Penelope, Igo, Robert P., Voss-Hoynes, Heather, Wren, Yvonne, Miller, Gabrielle, Truitt, Barbara, Zhang, Wen, Osterman, Michael, Freebairn, Lisa, Tag, Jessica, Taylor, H. Gerry, Chan, E. Ricky, Roussos, Panos, Lewis, Barbara, Stein, Catherine M., Iyengar, Sudha K.
Publicado 2021

Polymorphisms in TICAM2 and IL1B are associated with TB

por Hall, Noémi Borsay, Igo, Robert P., Malone, LaShaunda L., Truitt, Barbara, Schnell, Audrey, Tao, Li, Okware, Brenda, Nsereko, Mary, Chervenak, Keith, Lancioni, Christina, Hawn, Thomas R., Mayanja-Kizza, Harriet, Joloba, Moses L., Boom, W. Henry, Stein, Catherine M.
Publicado 2014

Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?

por McHenry, Michael L., Bartlett, Jacquelaine, Igo, Robert P., Wampande, Eddie M., Benchek, Penelope, Mayanja-Kizza, Harriet, Fluegge, Kyle, Hall, Noemi B., Gagneux, Sebastien, Tishkoff, Sarah A., Wejse, Christian, Sirugo, Giorgio, Boom, W. Henry, Joloba, Moses, Williams, Scott M., Stein, Catherine M.
Publicado 2020

Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

por Khawaja, Anthony P, Cooke Bailey, Jessica N, Wareham, Nicholas J., Scott, Robert A., Simcoe, Mark, Igo, Robert P., Song, Yeunjoo E., Wojciechowski, Robert, Cheng, Ching-Yu, Khaw, Peng T, Pasquale, Louis R, Haines, Jonathan L., Foster, Paul J, Wiggs, Janey L, Hammond, Chris J, Hysi, Pirro G
Publicado 2018

A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa

por Sobota, Rafal S., Stein, Catherine M., Kodaman, Nuri, Maro, Isaac, Wieland-Alter, Wendy, Igo, Robert P., Magohe, Albert, Malone, LaShaunda L., Chervenak, Keith, Hall, Noemi B., Matee, Mecky, Mayanja-Kizza, Harriet, Joloba, Moses, Moore, Jason H., Scott, William K., Lahey, Timothy, Boom, W. Henry, von Reyn, C. Fordham, Williams, Scott M., Sirugo, Giorgio
Publicado 2017

Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration

por Kopplin, Laura J, Igo, Robert P, Wang, Yang, Sivakumaran, Theru A, Hagstrom, Stephanie A, Peachey, Neal S, Francis, Peter J, Klein, Michael L, SanGiovanni, John Paul, Chew, Emily Y, Pauer, Gayle JT, Sturgill, Gwen M, Joshi, Tripti, Tian, Liping, Xi, Quansheng, Henning, Alice K, Lee, Kristine E., Klein, Ronald, Klein, Barbara EK, Iyengar, Sudha K
Publicado 2010

A Genome-Wide Search for Linkage of Estimated Glomerular Filtration Rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND)

por Thameem, Farook, Igo, Robert P., Freedman, Barry I., Langefeld, Carl, Hanson, Robert L., Schelling, Jeffrey R., Elston, Robert C., Duggirala, Ravindranath, Nicholas, Susanne B., Goddard, Katrina A. B., Divers, Jasmin, Guo, Xiuqing, Ipp, Eli, Kimmel, Paul L., Meoni, Lucy A., Shah, Vallabh O., Smith, Michael W., Winkler, Cheryl A., Zager, Philip G., Knowler, William C., Nelson, Robert G., Pahl, Madeline V., Parekh, Rulan S., Kao, W. H. Linda, Rasooly, Rebekah S., Adler, Sharon G., Abboud, Hanna E., Iyengar, Sudha K., Sedor, John R.
Publicado 2013

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

por Zein, Joe, Gaston, Benjamin, Bazeley, Peter, DeBoer, Mark D., Igo, Robert P., Bleecker, Eugene R., Meyers, Deborah, Comhair, Suzy, Marozkina, Nadzeya V., Cotton, Calvin, Patel, Mona, Alyamani, Mohammad, Xu, Weiling, Busse, William W., Calhoun, William J., Ortega, Victor, Hawkins, Gregory A., Castro, Mario, Chung, Kian Fan, Fahy, John V., Fitzpatrick, Anne M., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce, Mauger, David T., Moore, Wendy C., Noel, Patricia, Peters, Stephen P., Teague, W. Gerald, Wenzel, Sally E., Erzurum, Serpil C., Sharifi, Nima
Publicado 2020

Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)

por Williams, Robert C., Elston, Robert C., Kumar, Pankaj, Knowler, William C., Abboud, Hanna E., Adler, Sharon, Bowden, Donald W., Divers, Jasmin, Freedman, Barry I., Igo, Robert P., Ipp, Eli, Iyengar, Sudha K., Kimmel, Paul L., Klag, Michael J., Kohn, Orly, Langefeld, Carl D., Leehey, David J., Nelson, Robert G., Nicholas, Susanne B., Pahl, Madeleine V., Parekh, Rulan S., Rotter, Jerome I., Schelling, Jeffrey R., Sedor, John R., Shah, Vallabh O., Smith, Michael W., Taylor, Kent D., Thameem, Farook, Thornley-Brown, Denyse, Winkler, Cheryl A., Guo, Xiuqing, Zager, Phillip, Hanson, Robert L.
Publicado 2016