Phenotypic analysis of a transgenic Drosophila model of Alzheimer’s amyloid-β toxicity

por Sekiya, Michiko, Iijima, Koichi M.
Publicado 2021

Dissecting the daily feeding pattern: Peripheral CLOCK/CYCLE generate the feeding/fasting episodes and neuronal molecular clocks synchronize them

por Maruko, Akiko, Iijima, Koichi M., Ando, Kanae
Publicado 2023

Regulation of Energy Stores and Feeding by Neuronal and Peripheral CREB Activity in Drosophila

por Iijima, Koichi, Zhao, LiJuan, Shenton, Christopher, Iijima-Ando, Kanae
Publicado 2009

Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophil...

por Sakakibara, Yasufumi, Sekiya, Michiko, Fujisaki, Naoki, Quan, Xiuming, Iijima, Koichi M.
Publicado 2018

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

por Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Saido, Takaomi C., Iijima, Koichi M.
Publicado 2018

Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer’s disease

por Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Saido, Takaomi C., Iijima, Koichi M.
Publicado 2019

Alzheimer’s Disease-Related Phospho-Tau181 Signals Are Localized to Demyelinated Axons of Parvalbumin-Positive GABAergic Interneurons in an App Knock-In Mouse Model of Amyloid-β Pa...

por Hirota, Yu, Sakakibara, Yasufumi, Takei, Kimi, Nishijima, Risa, Sekiya, Michiko, Iijima, Koichi M.
Publicado 2023

Increasing neuronal glucose uptake attenuates brain aging and promotes life span under dietary restriction in Drosophila

por Oka, Mikiko, Suzuki, Emiko, Asada, Akiko, Saito, Taro, Iijima, Koichi M., Ando, Kanae
Publicado 2021

Distinct brain pathologies associated with Alzheimer’s disease biomarker-related phospho-tau 181 and phospho-tau 217 in App knock-in mouse models of amyloid-β amyloidosis

por Hirota, Yu, Sakakibara, Yasufumi, Ibaraki, Kyoko, Takei, Kimi, Iijima, Koichi M, Sekiya, Michiko
Publicado 2022

Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity...

por Ando, Kanae, Maruko-Otake, Akiko, Ohtake, Yosuke, Hayashishita, Motoki, Sekiya, Michiko, Iijima, Koichi M.
Publicado 2016

Heterogeneity of Microbial Communities on Deep-Sea Ferromanganese Crusts in the Takuyo-Daigo Seamount

por Kato, Shingo, Okumura, Tomoyo, Uematsu, Katsuyuki, Hirai, Miho, Iijima, Koichi, Usui, Akira, Suzuki, Katsuhiko
Publicado 2018

Mitochondrial Mislocalization Underlies Aβ42-Induced Neuronal Dysfunction in a Drosophila Model of Alzheimer's Disease

por Iijima-Ando, Kanae, Hearn, Stephen A., Shenton, Christopher, Gatt, Anthony, Zhao, LiJuan, Iijima, Koichi
Publicado 2009

Loss of Axonal Mitochondria Promotes Tau-Mediated Neurodegeneration and Alzheimer's Disease–Related Tau Phosphorylation Via PAR-1

por Iijima-Ando, Kanae, Sekiya, Michiko, Maruko-Otake, Akiko, Ohtake, Yosuke, Suzuki, Emiko, Lu, Bingwei, Iijima, Koichi M.
Publicado 2012

Disruption of a RAC1-centred network is associated with Alzheimer’s disease pathology and causes age-dependent neurodegeneration

por Kikuchi, Masataka, Sekiya, Michiko, Hara, Norikazu, Miyashita, Akinori, Kuwano, Ryozo, Ikeuchi, Takeshi, Iijima, Koichi M, Nakaya, Akihiro
Publicado 2020

Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration

por Sakakibara, Yasufumi, Yamashiro, Risa, Chikamatsu, Sachie, Hirota, Yu, Tsubokawa, Yoko, Nishijima, Risa, Takei, Kimi, Sekiya, Michiko, Iijima, Koichi M.
Publicado 2023

Physiological Mouse Brain Aβ Levels Are Not Related to the Phosphorylation State of Threonine-668 of Alzheimer's APP

por Sano, Yoshitake, Nakaya, Tadashi, Pedrini, Steve, Takeda, Shizu, Iijima-Ando, Kanae, Iijima, Koichi, Mathews, Paul M., Itohara, Shigeyoshi, Gandy, Sam, Suzuki, Toshiharu
Publicado 2006

Widespread Reduced Density of Noradrenergic Locus Coeruleus Axons in the App Knock-In Mouse Model of Amyloid-β Amyloidosis

por Sakakibara, Yasufumi, Hirota, Yu, Ibaraki, Kyoko, Takei, Kimi, Chikamatsu, Sachie, Tsubokawa, Yoko, Saito, Takashi, Saido, Takaomi C., Sekiya, Michiko, Iijima, Koichi M.
Publicado 2021

Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila

por Iijima, Koichi, Chiang, Hsueh-Cheng, Hearn, Stephen A., Hakker, Inessa, Gatt, Anthony, Shenton, Christopher, Granger, Linda, Leung, Amy, Iijima-Ando, Kanae, Zhong, Yi
Publicado 2008

5‐Aminolevulinic acid and sodium ferrous citrate ameliorate muscle aging and extend healthspan in Drosophila

por Nozawa, Naoko, Noguchi, Marie, Shinno, Kanako, Tajima, Maki, Aizawa, Shingo, Saito, Taro, Asada, Akiko, Ishii, Takuya, Ishizuka, Masahiro, Iijima, Koichi M., Ando, Kanae
Publicado 2021

A Miocene impact ejecta layer in the pelagic Pacific Ocean

por Nozaki, Tatsuo, Ohta, Junichiro, Noguchi, Takaaki, Sato, Honami, Ishikawa, Akira, Takaya, Yutaro, Kimura, Jun-Ichi, Chang, Qing, Shimada, Kazuhiko, Ishibashi, Jun-ichiro, Yasukawa, Kazutaka, Kimoto, Katsunori, Iijima, Koichi, Kato, Yasuhiro
Publicado 2019