A C-terminal peptide from type I interferon protects the retina in a mouse model of autoimmune uveitis

por Ahmed, Chulbul M., Ildefonso, Cristhian J., Johnson, Howard M., Lewin, Alfred S.
Publicado 2020

Inhibitors of metalloprotease, γ-sectretase, protein kinase C and Rho kinase inhibit wild-type adenoviral replication

por Liu, Alice, Ildefonso, Cristhian J., Bond, Wesley S., Hurwitz, Mary Y., Hurwitz, Richard L.
Publicado 2020

Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa

por Massengill, Michael T., Ash, Neil F., Young, Brianna M., Ildefonso, Cristhian J., Lewin, Alfred S.
Publicado 2020

Versican G1 domain enhances adenoviral-mediated transgene expression and can be modulated by inhibitors of the Janus kinase (JAK)/STAT and Src family kinase pathways

por Akinfenwa, Patricia Y., Bond, Wesley S., Ildefonso, Cristhian J., Hurwitz, Mary Y., Hurwitz, Richard L.
Publicado 2017

Corneal Application of R9-SOCS1-KIR Peptide Alleviates Endotoxin-Induced Uveitis

por Ahmed, Chulbul M., Patel, Anil P., Ildefonso, Cristhian J., Johnson, Howard M., Lewin, Alfred S.
Publicado 2021

Repurposing an orally available drug for the treatment of geographic atrophy

por Ahmed, Chulbul M., Biswal, Manas R., Li, Hong, Han, Pingyang, Ildefonso, Cristhian J., Lewin, Alfred S.
Publicado 2016

Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors

por Brown, Emily E., DeWeerd, Alexander J., Ildefonso, Cristhian J., Lewin, Alfred S., Ash, John D.
Publicado 2019

Systematic Review and Meta-Analysis of the Association between Complement Factor H I62V Polymorphism and Risk of Polypoidal Choroidal Vasculopathy in Asian Populations

por Wang, Zhao-Yang, Zhao, Keke, Zheng, Jingwei, Rossmiller, Brian, Ildefonso, Cristhian, Biswal, Manas, Zhao, Pei-quan
Publicado 2014

Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD

por Biswal, Manas R., Han, Pingyang, Zhu, Ping, Wang, Zhaoyang, Li, Hong, Ildefonso, Cristhian J., Lewin, Alfred S.
Publicado 2017

Expression of a CARD Slows the Retinal Degeneration of a Geographic Atrophy Mouse Model

por Young, Brianna M., Jones, Kyle, Massengill, Michael T., Walsh, Erin, Li, Hong, Lewin, Alfred S., Ildefonso, Cristhian J.
Publicado 2019

Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness

por Wang, Yixiao, Snell, Aaron, Dyka, Frank M., Colvin, Elizabeth R., Ildefonso, Cristhian, Ash, John D., Lobanova, Ekaterina S.
Publicado 2023

AAV Mediated Delivery of Myxoma Virus M013 Gene Protects the Retina against Autoimmune Uveitis

por Ridley, Raela B., Young, Brianna M., Lee, Jieun, Walsh, Erin, Ahmed, Chulbul M., Lewin, Alfred S., Ildefonso, Cristhian J.
Publicado 2019

Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa

por Massengill, Michael T., Young, Brianna, Patel, Deep, Jafri, Farwa, Sabogal, Ernesto, Ash, Neil, Li, Hong, Ildefonso, Cristhian J., Lewin, Alfred S.
Publicado 2018

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide

por Ildefonso, Cristhian J., Jaime, Henrique, Brown, Emily E., Iwata, Ryo L., Ahmed, Chulbul M., Massengill, Michael T., Biswal, Manas R., Boye, Shannon E., Hauswirth, William W., Ash, John D., Li, Qiuhong, Lewin, Alfred S.
Publicado 2016

Deriving Immune Modulating Drugs from Viruses—A New Class of Biologics

por Yaron, Jordan R., Zhang, Liqiang, Guo, Qiuyun, Burgin, Michelle, Schutz, Lauren N., Awo, Enkidia, Wise, Lyn, Krause, Kurt L., Ildefonso, Cristhian J., Kwiecien, Jacek M., Juby, Michael, Rahman, Masmudur M., Chen, Hao, Moyer, Richard W., Alcami, Antonio, McFadden, Grant, Lucas, Alexandra R.
Publicado 2020